Wonke umntu uyazi ukuba inqanaba le-cholesterol eliphakamileyo liyingozi enkulu ye- coronary artery disease (CAD) . Ukuba unomngcipheko ophezulu wokuphuhlisa i-CAD, okanye ngokukodwa ukuba sele unayo i-CAD, unokuqiniseka ukuba ugqirha wakho uya kunxusa ukuba unciphise amazinga e-cholesterol yakho, kwaye uya kubeka isigxina se- statin ukukunceda wenze njalo.
Ngoko kungenzeka kukuba abantu abangaphezu kweminyaka engama-65 - iqela elidala elinesiganeko esiphezulu se-CAD - enokukwenza malunga namazinga e-cholesterol ephakamileyo sele aphikisana.
Kutheni Iingxabano?
Ingxabano ikhona kuba abantu asebekhulile baye bakhankanywa ngokuchanekileyo kwiinkoliso ezininzi zeeklinikhi ezibonisa iingenelelo zonyango lwe-cholesterol. Ngenhlanhla ukuba izilingo zamachiza zonke iintlobo ziye zazinqwenela ukugweba ukubhalisa izigulane ezigugile.
Oku akubangenxa yokuba iinkampani zonyango zijonga abantu abadala ukuba bangafanelekanga ngqalelo yabo, kodwa kunokuba izizathu ezifanelekileyo kunye nezomnotho. Abantu abadala baye banciphisa ixesha elide lokuphila, ngoko abanye babo bafa ngexesha lokuvavanywa kwexesha elide ngenxa yezizathu ezingahambelani nxamnye novavanyo oluhlolwe. Kwakhona, abantu asebekhulile banamathuba angaphezu kwesinye sezokwelapha, ngoko baninzi bafumana iimpawu - ezinye zazo zingaphathwa ngokuchanekileyo kubangelwa ukusetyenziswa kweziyobisi. Ukufa okunjalo "okungafaniyo" kunokuba nzima kakhulu ukuhlalutya ityala lekliniki kwaye kungasongela ukuvunyelwa kwe-FDA ngokutsha kwesilwanyana esitsha.
Ngoko kuye kwakhuseleka (kwaye kungabizi) ukushiya abantu abadala kwiinkampu ezininzi zeeklinikhi.
Lo mkhuba wokuxhomekeka uthetha ukuba siyazi ngokuncinci malunga neenzuzo ezithile kunye neengozi zokuphatha amanqanaba aphezulu e-cholesterol kubantu abadala. Kwaye oku, oko kuthetha ukuba xa isigulane esiphelile sinamazinga aphezulu e-cholesterol, oogqirha abahlala beqinisekile ukuba kufuneka banikele unyango.
I-Cholesterol kunye Nezifo Zeentliziyo Zasebekhulile
Kubantu bobabini ngokwesini abaneminyaka engama-65, isifo senhliziyo sisenza ngaphezu kwesigamu sazo zonke ukufa. Ngokuthelekiswa, umdlavuza uvelisa "kuphela" i-24% yokufa kwabasilisa kule nqanaba elifanayo kunye no-20% kwabasetyhini. Ngoko unyango olunokunciphisa ingozi yesifo senhliziyo kubantu asebekhulile kufuneka ibe yinto enqwenelekayo.
Ukongezelela, i-cholesterol ephakanyisiweyo ihambelana nobungozi besifo senhliziyo kubantu abadala njengokuba kunjalo kubantu abancinci. Enyanisweni, ubuncinci bunye bubungqina bokuba i-cholesterol ingaba yinto ebaluleke kakhulu kubungozi kubantu abadala.
Ngaba Kuyincedo Ukunciphisa Amanqanaba e-Cholesterol kubantu abadala?
Nangona kunqongophala kobubungqina bezilingo zekliniki kubantu abadala, ukuxhomekeka kobungqina kubonisa ukuba ukhathalela i-cholesterol ephakamileyo kwi-asebekhulile yinto ekufuneka iqwalaselwe ngamandla.
Idatha ewaneleyo ifumaneka kwiinkalo ezininzi zeemvavanyo zonyango kwi-cholesterol unyango ukuvumela ukuhlaziywa kwamacandelo kubantu abadala. Izifundo zokudibanisa idatha kwizinye zezi zilingo ziye zagqiba ukuba iziphumo zengqondo zingaphuculiswa ngokunyanga amazinga e-cholesterol aphezulu kunye namachiza e-statin kubantu asebekhulile ubuncinci kunabantu abancinci.
Ukongezelela, ukunciphisa ingozi yomzimba kubantu abadala kudlalwa kwinyanga nje ezimbalwa zokuqala unyango, ngoko nangona izi gulane zidala, "azindala" ukuba zifumane iinqununu ze-cholesterol ehlahlayo kunye nama-statins.
Ngoko ke, nangona iimeko ezinokubangela ukunyuka kwe-cholesterol zingabonakaliswa ngokucacileyo kubantu abadala kunabantu abancinci, ubungqina obuninzi obufumanekayo bubonisa ukuba kunenzuzo enkulu ekunakekeleni i-cholesterol ekhulile.
Imiphumo emibi yeeNkcazo kubantu abadala
Ubungqina obukhoyo bubonisa ukuba umngcipheko weempembelelo ezivela kwiimimiselo awukho ngaphezulu kwizigulane ezinde kunezona zigulane ezincinci.
Nangona kunjalo, boogqirha kunye nezigulane kufuneka ziqwalasele ukuba ezinye zeempembelelo ezinobungozi zeemimiselo (ezinjengeengxaki ze- muscle kunye neengxaki zengqondo ) zingabangela ukuba zilungele ngakumbi kwizigulane ezincinci kunezigulane.
Ngaphantsi
Ukuba ungumntu omdala onomngcipheko we-cardiac - okanye mhlawumbi ukuba unayo i-CAD - nangona kukho ukungabikho kobungqina obucacileyo bokunyanga i-cholesterol yakho inenzuzo, kukho ubungqina obaneleyo ukuba kube yinto efanelekileyo ukuba ingxoxo malunga neyeza le-cholesterol kunye nogqirha wakho.
Kubantu abadala abanobuninzi beengxaki zezokwelapha, ubunobungozi bokungeza elinye iyeza kwi-regimen esele yinkimbinkimbi esele ixakeke kakhulu kunokuba luncedo kakhulu. Kodwa kubantu abadala asebekhulile abanezinga eliphezulu le-cholesterol, unyango lwe-cholesterol-unciphisa unyango kufuneka uqwalaselwe ngokucokisekileyo.
Imithombo:
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Wenger NK, Lewis SJ, uHerrington DM, et al. Iziphumo zokusebenzisa i-atorvastatin ye-high-or-low-doorvastatin kwizigulane ezingama-65 ubudala okanye ngaphezulu kunye nesifo senhliziyo esisigxina. Ann Intern Med 2007; 147: 1.
Sacks FM, Tonkin AM, uMalusi J, et al. Impembelelo ye-pravastatin kwiziganeko zesifo se-coronary kwizigqeba ezichazwe yimiba yengozi ye-coronary: Project Prospective Pravastatin Pooling Project. Ukujikeleza 2000; 102: 1893.
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