Kuye kucaciswa ukuba i- Accutane (i-isotretinoin) inokuthi ixhunyezwe ekuphuhlisweni kwesifo sesibindi (IBD) . Ulwazi lwesigulane se-Accutane luyavuma ukuba unxibelelwano phakathi kweziyobisi kunye ne-IBD. Izigwebo ezininzi ziye zaziswa ngokumelene neRoche Holding AG, abenzi be-Accutane, ezinye zazo eziye zaphumela kwizigwebo ezinxulumene nenkampani yezobisi.
Ezinye zezo zigwebo zagqitywa emva koko , kwaye abanye basalindelwa. I-Accutane yayisuswe ngokuzithandela kwimarike ngoJuni 2009, kodwa iinguqulelo zesiqhelo zisasafumaneka.
Uphando Lithini?
Olunye uphando luphelile ukuba le nkunkuma ingabangela ukuba izigulane ezithile ziqalise i-IBD . Ukuhlaziywa kuka-2009 kwincwadi efunyenwe ukuba akukho ubungqina obaneleyo bokungqina okanye ukuphikisa ukudibanisa phakathi kweziyobisi kunye nophuhliso lwe-IBD. Uvavanyo lwe-case-control lwango-2010 lubonise ukuba i-Accutane inxulumene nomngcipheko omncinci wokuvelisa i-ulcerative colitis, kodwa akukho nxu lumene nesifo sikaCrohn. Ababhali beli phofu babonisa ukuba umngcipheko we-ulcerative colitis ungabandakanywa nama-dosage aphezulu ase-Accutane. Isifundo sesithathu saphetha ukuba abantu abathatha i-Accutane abangekho okanye banako ukuphuhlisa i-IBD kunoma ubani, kodwa bavuma ukuba kukho iingxelo ze-IBD-Accutane.
Antibiotics kunye ne-IBD
Kanti olunye uphando lwango-2010 lubonise ukuba ii-antibiotics ezithile eziqhelekileyo ezibhekiselelwe ekuphatheni i- acne enamandla zingabandakanywa nophuhliso lwe-IBD . Ezi antibiotics zidla ngokuthatha ixesha elide, kwaye xa zihluleka ukulawula i-acne, i-Accutane isoloko ikhethwa ngokuzayo kunyango.
Ababhali belo cwaningo baxela ukuba ukusetyenziswa kwe-antibiotics kwangexesha elide ngokwenene kungabangela ukuba i-IBD iqale kwaye kusengacacanga ukuba i-Accutane ingafanelana njani nomxube.
Uxhumano phakathi kwe-Acne ne-IBD
Ukuhlaziywa okwenziweyo ngo-2011 kucatshangelwe ukuba kunokwenzeka ukuba kunxibelelwano phakathi kwe-acne ne-IBD. I-acne ebonakalayo kunye ne-IBD ziimeko zombini ezivuthayo, kwaye bobabini bahlala bevavanywa kwiintsholongwane kunye nabantu abadala. Ababhali baqhubeka bembonisa ukuba ukuba umntu omncinci unyamekela ngugqirha, kukho ezinye iimeko (njenge-IBD) ezichongiweyo.
Ngaphantsi
Zonke ezi zifundo zibonisa ukuba kukho ubungqina bokuxhasa inkxaso-mabango ukuba i-Accutane ibangela i-IBD kunye nesibango sokuba i-Accutane ayibangeli IBD. Oku akuncedi naliphi na umntu ocinga ngonyango lwe-Accutane, okanye kwabo basebenzise i-Accutane esikhathini esidlulileyo, kodwa kaninzi ngolu hlobo uphando lwezobugcisa lusebenza. Kungathatha iminyaka ukuvumelanisa ngokubanzi ukuvela kwiincwadi zonyango. Inkundla inkundla ibali elihlukileyo, kwaye izigwebo zingabangela isigwebo malunga naluphi na icala lo mbandela.
Emva kokuphonononga lo bungqina, umntu unokuzibuza ukuba uphando luya ngaphaya komendo: ngaba kukho ulwalamano phakathi kwe-IBD kunye ne-acne?
Mhlawumbi kwezinye zeemeko, i-IBD yayisele ikhona, kodwa ayizange ifumaneke emva kokunyangwa kwe-Accutane. Akukho okwangoku kukho ubungqina okanye ngokuchasene nale ngcamango. Nangona kunjalo, ku funeka kuqatshelwe ukuba i-steroids (ngokukodwa i- prednisone ), enye yezokwelapha eziqhelekileyo kwi-IBD, inokubangela i-acne enzima .
Iingqwalasela Ngokuphathelele Ukunyangwa kwama-Acne
Ukuba ucinga ukusebenzisa i-Accutane , okanye ukuba usebenzisa le michiza esikhathini esidlulileyo kwaye uxhalabele nge-IBD, kufuneka uxoxe nomngcipheko wakho kunye nesikhombiso sakho sembewu. Gcina ukhumbule ukuba ukuba kukho umngcipheko wokuphuhlisa i-IBD emva kokuthatha i-Accutane, kusengokuqhelekanga.
Olunye uphando olwenziwa ngo-2011 olwenziwa ngo-2011 lubonisa ukuba abo bacinga ukuthatha i-Accutane baqaphele umngcipheko omncinci wokwenza i-ulcerative colitis.
Kubantu abasele benayo i-IBD, ngakumbi i-ulcerative colitis, kwaye ngubani ofuna unyango lwe- acne ekhulayo , unyango lokuqala luhlala lunama-agent. Ukuba unyango lwamayeza alusebenzi, i-antibiotics kunye ne- antimicrobials zingasetyenziswa.
Imithombo:
I-Accutane Information Patient Information. Roche. 2 Septemba 2010.
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