Uphando olutsha luye lwabonisa ukuba izidakamizwa ze-statin zinokunyusa kakhulu umngcipheko wokwenza i- cataracts . Abaphandi baseSan Antonio Hospital Medical Centre eTexas baqhube uphando olwakubandakanya ama-6972 amabini abasebenzisi be-statin nabasebenzisi abangabonakaliyo. Bafumanise ukuba uphuhliso lwe-cataract lwalu-27% oluphezulu kumsebenzisi wabasemthethweni. Abaphandi babonise ukuba isifundo asiyiyo yonke into kwaye akukho nanye ibonisa ubungqina kunye nobudlelwane.
Nangona kunjalo, abaphandi bathi ukusetyenziswa kwe-statin kubonakala kuhambelana nobuncipheko obuninzi bokuphuhlisa i-cataract.
Izidakamizwa zeStatin zibangelwa njani iCataracts?
Kuyaziwa ukuba umonakalo we-oxidative unomthwalo onoxanduva lokuphuhliswa kwama-cataracts. Iimpawu zineempembelelo ze-bidirectional kwiinkqubo ze-oxidative ezingenako ukwandisa umngcipheko we-cataract. Olunye uphando lucacisa ukuba i-cholesterol ephakamileyo iyadingeka ngaphakathi kweeseli eziphuhliswa ngaphakathi kwilensi kwaye kuyadingeka ukugcina ukukhanya kwayo. Ngenxa yoko, ama-statins angayivimba le nkqubo eyenza i-cataract iphuhlise. Kuye kwaphawulwa ukuba abantu kunye nezilwanyana ezinesifo se-cholesterol esinezifuba zinomngcipheko okhulayo wokwenza i-cataracts.
Uphando oluninzi lufanelekile. Nangona uphando oluninzi olubandakanya i-statin nokusebenzisa i-cataracts ziqaphele ukucoca izinto ezinzima ezinokuchaphazela ukufundisisa, izinto ezifana nesifo sikashukela sinokuthi zifake iziphumo.
Izigulane ezininzi zesifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo sikasifo se-cardiovascular disease. Izigulane zesifo sikasifo se-Diabethe sele sele sengozini yokukhula kwimeko engaphambili kunye neyingozi kakhulu kunabantu abanesifo sikashukela. Ukuyinkcenkceshela umfanekiso ngakumbi, kukho iinjongo ezithile kwixesha elidlulileyo elibonise ukuba i-statins inokunciphisa ukuphuhliswa kwe-cataract.
Ziziphi iiStatin?
Ummiselo yiklasi leziyobisi ezisetyenziselwa ukunciphisa amanqanaba e-cholesterol emzimbeni. Izidakamizwa zeStatin zisebenza ngokuthintela isenzo sekhemikhali ethile esesibindi esenza i-cholesterol. Sonke sidinga inqanaba le-cholesterol emzimbeni wethu. I-cholesterol iyadingeka ukuba iiseli zethu zisebenze ngokuchanekileyo. Nangona kunjalo, amazinga angavamile we-cholesterol angakhokelela kwi-atherosclerosis. I-atherosclerosis ibangelwa yi-cholesterol plaques ezakhayo emitanjeni yegazi kunye nokuvimba ukuhamba kwegazi ngokuqhelekileyo. Ummiselo unokunciphisa i-cholesterol ehlisa umngcipheko wokuhlaselwa kwintliziyo kunye nesifo. Imizekelo yemimiselo yiPicitor, Pravachol, Crestor, Zocor, Lescol noVytorin.
Ziyintoni iCataracts?
I-cataract i-clouding ye- lens eye. I-Cataract iyona nto ibangela ukuphosa phakathi kwabantu abadala kunama-55. Abaninzi abantu asebekhulile banomlinganiselo othile we-lens clouding, eyinto eqhelekileyo yokuguga. I-lens itholakala emva kwe-iris. Inoxanduva lokugxila ekukhanyeni kwi-retina, kunye nokuvelisa imifanekiso ecacileyo, ebukhali. I-lens inekhono lokutshintsha isimo, eyaziwa ngokuthi indawo yokuhlala. Njengoko ilanga lemihlo, kunjalo, i-lens iyanzima kwaye ilahlekelwe yikhono layo lokuhlala. Iiseli ezifile okanye iitshintshi zitshintshiweyo zigcinwe kwi lensi, okwenza ukuba ilensi ibe yinto efutshane.
Ukukhanya okuqhelekileyo kugxininiswe yilensi yahlakazeka ngeenxa zonke ngenxa yokukhanya, umbono onjalo awusayi kucace kwaye ubukhali.
Iingxaki ze-cataract ngokuvamile zizintlungu. Ngokuqhelekileyo ziqala njengendawo encinci, i-opaque kwaye ikhula ngokukhawuleza. Umbono awunakuthi uchaphazeleke kude kube yindawo enkulu yeli lensi ibe yinto efufayo. Ezi zimpawu zilandelayo zenzeka nge-cataract:
- Umbono ongezantsi
- Ukukhanya kokukhanya
- Halos zijikeleze izibane
- Umbono wobusuku obuthathaka
- Ukuqhwala okanye ukubola kombono
- Umbono ombini
- Utshintsho kweso sigxina
Oko Okufanele Uyazi
Kubalulekile ukubonisa ukuba kungabi ngqiqweni ukuyeka ukuthatha imithi yakho ye-cholesterol nje ngenxa yokwandisa umngcipheko we-cataracts.
Utyando lweCataract ngokuqhelekileyo luyimpumelelo kakhulu, enyanzeliswe kakuhle, ngelixa i-cholesterol ephakamileyo inokunyusa kakhulu umngcipheko wokuhlaselwa kwintliziyo, ukushaywa kwesifo kunye nokufa. Ugqirha wakho kufuneka axoxe nawe ukuba ukuthatha izitembu ziboniswe kwezinye iinjongo ukwenzela ukwandisa umngcipheko wokuhlakulela i-cataracts.
> Imithombo:
> Leuschen, uJessica ND. Umbutho we-Statin Usetyenziso lwe-Cataracts: I-Score-Propist Score-Ukuchongwa koHlolo. JAMA Ophthalmology, ngo- 2013.