Ingxaki ye-Migraine ineengcambu zemizimba, kodwa izinto ezongezelelweyo zibandakanyeka.
I-Migraines ithambekele ekusebenzeni kwiintsapho. Ngenxa yoko, abaphandi bakholelwa ukuba le miqobo ingumthombo wezityalo kunye nokuba i-migraines ifa, kodwa sele iqalile ukucwangcisa ukuba yiyiphi igalelo echaphazelekayo kunye nendlela ezo zakhi zisebenzisana ngayo nendawo yakho yokuvelisa intloko.
Kukho iintlobo ezahlukeneyo ze-migraine, kwaye ezi zidibeneyo zibe zigaba ezimbini eziqhelekileyo: i- migraine ne-aura kunye ne- migraine ngaphandle kwe-aura .
Boba bobabini babonakala benama-genetic links, benza ukuba bazuze.
Uphando lweewele ezifanayo kunye nobudlelwane lubonisa ukuba ukuya kwesigamu sesigxina se-migraine ngenxa yemfuza yezinto eziphilayo, kunye nemingcipheko yemfuzo ye-migraine ne-aura xa kuthelekiswa ne-migraine ngaphandle kwe-aura.
Oko kuthetha ukuba iizakhi zakho zingaphatha isisombululo esibalulekileyo somngcipheko wokuba nesifo se-migraine-ukuya kwisiqingatha, njengoko ndithethile-kodwa ezinye izinto zinegalelo. Ukuhlalutya le mvelaphi yezofuzo kunye neyoyiyo ingabangela ukuba kubekho unyango olululo.
I-Migraine enamandla neAura: I-Genetic Links Ecacileyo
Xa befuna iizakhi ezithile ezixhomekeke kwizifo ezifudulayo, abaphandi baqale bafunda uhlobo oluthile lwe-migraine enamandla kunye nera ebizwa ngokuba yi-familial hemiplegic migraine.
Kulo hlobo lwe-migraine ne-aura, abantu banenkxwabo yecala kunye nobuthathaka besikhashana, ngokuqhelekileyo kuphela kwicala lomzimba wabo, njengokuba i-aura ibamba ("i-hemiplegic" ibonisa nje oko kwenzeka kwicala elinye lomzimba).
Iimbandezelo nazo zinokufumana iintetho ezinzima okanye ezinzima, ukudideka nokulala.
I-familial hemiplegic migraine inokubangela ukuba i-migraine ibe nefuthe kakhulu emagqabini enomkhuhlane, ukuxhatshazwa kunye ne-coma. Ukufa kula ma-migraine kuye kwenzeka kwiimeko ezimbalwa, kwaye malunga nama-20% abantu abachaphazelekayo bakhula iingxaki ezisisigxina ngokulinganisela, ukulungelelanisa kunye nokunyuka kwamehlo.
Izixhumanisi zofuzo kuloluhlobo lwe-migraine zicacile kwaye zibandakanya ubuncinane ubuncwane abane-jeni, nganye kubonakala ngathi inendima ekulawuleni i-neurotransmitters ezixelela ubuchopho bethu ukuba benzani. Uphando lo kuqala kwi-familial hemiplegic migraine lwalusisiseko sokujonga ngokuthe ngqo i-migraine genetics ngokubanzi.
Iimpawu zeMigraine ezongezelelweyo zichongwe
Okwangoku, uphando oluthile luye lwafumanisa ubuncinane i-13 zegciwane ezingabangela ukuba umntu abe neengxaki zokuthatha izifo. Ezi zintathu zazo zichaphazela i-neurotransmitter ethile, i- glutamate , ngelixa ezinye zichaphazela amandla okwenza i-neurons ukuba iphathe ngendlela eqhelekileyo.
Oososayensi bacacisa ukuba ukuhlanganiswa kwezofuzo kungakhokelela ekubeni ingqondo "ibe yinto efanelekileyo" -kuthetha ukuba ibangela ukwanda komsebenzi kwiindawo ezithile zengqondo ebonakala ngathi ihambelana nentlungu kunye nezinye iimpawu zesifo se-migraine. Nangona kunjalo, akukho bungqina obucacileyo beli ngcamango okwamanje.
Akwacaca nokuba ezinye zezi zixhobo zihlukile kwi-migraine, kuba enye indlela ebonakala ibangela ukuba intlungu ye-migraine iyenzeka nakwezinye iimeko, kubandakanywa nesifo sengqondo sesisu , i- fibromyalgia kunye neentlungu ezisezantsi.
I-Genetics ebalulekileyo kwiZonyango ezizayo
Ingaba ubiza ngokuthi "i-migraine," "isifo se-migraine" okanye "i-migraine disorder," i-migraine yinto ephindaphindiweyo, i-episodic, yezifo zesifo segazi.
Oko kuthetha ukuba imigraineurs inesifo sengqondo ngaso sonke isikhathi, kungekhona nje xa i-migraine ingenawo.
Oku kunokukunceda ukuthelekisa ukuhluthwa kwesinye isifo, esinye isifo sengqondo esivayo. Abantu abanesifo sokuhluthwa banenkinga ngexesha lonke, nangona bengenazo iziqulatho, kunye nenjongo yokhathalelo lwabo lwezonyango kukugcina ingxaki yokulawulwa kwezifo ukuze iphephe iziqephu.
Izazinzulu zithemba ukuba ngokuchonga iindidi ezahlukahlukeneyo ezinokuba negalelo lokufudumala komngcipheko, ziyakwazi ukuqulunqa iziyobisi kunye nezinye izigulana ezijolise kwiingxaki ezibangelwa yizo zityalo. Ekubeni i-migraines ingakwazi ukukhubaza kakhulu, kunye nemiphumo emihle emsebenzini wakho, intsapho yakho kunye nempilo yakho yonke, nayiphi na impumelelo kwi-grazil migraine esekelwe kwiijethi zakho ziza kuwamkela.
Imithombo:
Burstein R et al. I-Migraine: Iinkqubo ezininzi, i-Complex Pathophysiology. I-Journal ye-Neuroscience. 2015 Apreli 29; 35 (17): 6619-6629.
Honkasalo ML et al. I-Migraine kunye neempawu ezidibeneyo phakathi kwama-8167 amabini amawele omdala. Intloko. 1995 Feb; 35 (2): 70-8.
Iziko zeSizwe zeeMpilo zeMpilo zeGenesis. Iphepha lohlobo lweHemiplegic Migraine. Kufikeleleka ngoNovemba 20, 2015.
Piane M et al. I-Genetics ye-migraine kunye ne-pharmacogenomics: ezinye iinkalo. Umbhalo weNtloko yesisu. 2007 Dec; 8 (6): 334-339.
Smitherman TA et al. Ubuninzi, impembelelo, kunye nokunyanga kwe-migraine kunye neentloko ezinzima e-United States: ukuhlaziywa kweenkcukacha ezivela kwizifundo zohlolo lwelizwe. Intloko. 2013 Mar; 53 (3): 427-36.