Ekubeni incwadi ethi "I-Arthritis Cure" yayithengiswa kwii-bookstores kulo lonke ilizwe ngo-1997, oogqirha, oomachiza, kunye nabaxhamli be-arthritis bavame ukucelwa umbono wabo we-glucosamine njengonyango lwe-arthritis . Igama elithi "unyango" kwisihloko sencwadi laphakamisa ithemba labaninzi abahluphekileyo ngesifo.
Indlela i-Glucosamine isebenza ngayo
I-Glucosamine ifumaneka kwiindawo eziphezulu kwizihlanganisi .
Kuye kwachazwa ukuba i-glucosamine ivuselela ukubunjwa kwe-cartilage ebalulekileyo ekulungiseni ngokuhlangeneyo. Kwiimpawu zezilwanyana, umlomo we-glucosamine sulfate unempembelelo ekuvukeleni, isifo samathambo, kunye ne-immunological-active acthritis, nangona kunjalo kuncinci kune-indomethacin kunye nezinye iziyobisi.
I-Glucosamine ngamanye amaxesha isetyenziswa ngokudibanisa ne-chondroitin sulfate njengonyango lwe-arthritis. I-sulphate yeChondroitin ifumaneka kwi-cartilage. I-sondate i-Chondroitin ibikwa ukuba igcina i-viscosity kwizihlanganiso, ivuselela iindlela zokulungisa i-cartilage, kwaye ikhubaza i-enzymes ephula i-cartilage.
Supplementary Supplement
I-Glucosamine ithengiswa eUnited States njengesongezelelo sokutya. UMthetho wezeMpilo wezeMpilo kunye noMthetho owenziwe ngo-1994 yiCongress uvumela ukuthengiswa kwemveliso ebanjelwe ukuba ifuthe isakhiwo okanye umsebenzi womzimba "njengesondlo sokutya" ngaphandle kokuvunyelwa nayiphi na i-arhente karhulumente.
Ukubhaliweyo kufuneka kufake i-disclaimer ukuba imveliso ayizange ihlolwe yi-FDA kwaye loo mveliso ayihloselwe ukuxilonga, ukunyanga okanye ukuthintela nasiphi na isifo. I-Glucosamine ifumaneka kwii-pharmacy kunye nezitolo zokutya zempilo njenge-sulfate, i-hydrochloride, i-n-acetyl, okanye ityuyidrate ityuwa.
Studiical Studies
Izifundo ezifutshane ezilawulwe ngokukhawuleza zitshilo i-glucosamine njengendlela ephumelelayo ekunciphiseni ubuhlungu kwizigulane ezine-osteoarthritis kunye nokwandisa uluhlu lwazo lwenkqubela .
Iviki ezine ezineveki eziyimfama ezingama-252 ezine-osteoarthritis zamadolo zathola umlomo we-glucosamine sulfate 500 mg. kathathu ngosuku olusebenzayo ngakumbi kune-placebo ekunciphiseni iimpawu.
Olunye uvavanyo lweeveki ezine eziziimfama ezingama-200 zezigulane ezine-osteoarthritis zamadolo zityhila i-500 mg. ye-glucosamine sulfate njengendlela ephumelelayo ekunciphiseni iimpawu njenge-ibuprofen 400 mg. kathathu ngosuku, emva kweveki yesibini.
Kwisifundo seveki ezisibhozo ezingaboniyo ezingama-40 zezigulane ezine-osteoarthritis, i-glucosamine sulfate 500 mg. kathathu ngosuku ngomlomo kwakusebenza ngempumelelo njenge-ibuprofen 400 mg. kathathu ngosuku ukukhulula intlungu emva kweveki ezimbini zokuqala. Kuzo zonke iingxelo i-glucosamine yayivunyelwa ngokunyameko kunye neemeko zesisu esiswini esingekho ngaphezu kwe-placebo.
Ezi zifundo, nangona iziphumo ezinqwenelekayo azizange zithathwe njengezifundo ezicwangciswe kakuhle. Izifundo ezicwangciswe kakuhle maziqhutywe kusetyenziswa inani elaneleyo lezigulane ngaphezu kwexesha elaneleyo, ubuncinane ngonyaka, ngabaphandi abanolwazi, ukusebenzisa amanyathelo enjongo kunye neendlela zobalo ozinokumisela ukuba ukuphucula kuyiphumo elichanekileyo lonyango. Ezi zifundo zadibana neendlela ezincinci kwaye zaqhutywa kwizigulane ezimbalwa kakhulu.
Ngokomzekelo we-2004 waseCanada, okubandakanya izigulane ezili-137, akukho mfahluko omkhulu phakathi kwepesenteji yabathathi-nxaxheba abavuthayo kwiqela le-placebo kunye neqela le-glucosamine.
Kwintlanganiso ye-ACR yonyaka ka-2005, iziphumo ezivela kwimizamo emibini ye-glucosamine. I-GAIT (iGlucosamine / Chondroitin I-Arthritis Intervention Trial) yaxhaswa ngemali yi-NIH kwaye yenzelwe ukufumana ukhuseleko kunye nokusebenza ngempumelelo kunye ne-glucosamine, i-chondroitin, ithathwe ngokwahlukileyo okanye kunye kunye, kunye ne-GUIDE (iGlucosamine Unum In Die Efficiency) yilingo leYurophu. IINKHONO ZOKUKHONZISA zibonisa i-glucosamine yanikezela ngakumbi uncedo kune-acetaminophen.
Iimpembelelo ze-GAIT zibonisa ukuba ukuhlanganiswa kwe-glucosamine kunye ne-chondroitin kungcono kune-placebo kodwa iinzuzo zibonakala zixhomekeka kubukhulu beentlungu. Kwizigulane ezinobunzima be-knee osteoarthritis , inxalenye ye-glucosamine chondroitin ayizange iphumelele ngakumbi kune-placebo.
- I-Glucosamine Trial Results Ebekwe kwi-ACR Meeting 2005
- Ingakanani i-Glucosamine ifanele isithathe isifo?
Isiphelo
Ingavumelwane kukuba i-glucosamine kunye ne-chondroitin isongezelelo kunokunciphisa intlungu kwezinye izigulane ezine- osteoarthritis. Oogqirha abaninzi ngoku bakholelwa ukuba kulungele ukuzama ezi zongezelelo ze-osteoarthritis. Ziyabonakala zikhuselekile, kodwa oogqirha bayalumkisa izigulane ukuba umgangatho kunye nokusebenza kwe-glucosamine kunye ne-chondroitin ziyahluka ngenxa yokungahambisani nomthetho. Ukuba ufuna ukuzama, bathenge iimveliso eziphezulu ezivela kumthombo ohloniphekileyo.
Imithombo:
Incwadi Ethembisa Ukunyanga, I-Arthritis Namhlanje, ngoMeyi-Juni 1997
Zama iGlucosamine kwi-OA, iArthritis namhlanje, ngoJulayi-Agasti 1998
I-Glucosamine yeArthritis, ngo-1997 Incwadi Yonyango, Ikhasi leKhaya le-Quackwatch