Ingozi iphindwe ngama-58 ngaphezu kobonke abantu
Ingxaki iqala ngokungenasiphelo ngokungahambi kakuhle kumlenze, ngokukodwa kwindawo yokuhluma. Kamva, intlungu iba nzima kakhulu kwaye iqala ukubandakanya i-hip. Ngethuba elifutshane, ukuhamba kuya kuba nzima, kwaye intlungu iya kukhula ngamandla kuze kube yilapho ekugqibeleni ungazibaleki. Yiyo kuphela le nqanaba abantu abaninzi baya kubona ugqirha.
Phakathi kwabantu abane-HIV, ezi ntlobo zeempawu zingathetha naziphi na izinto, ezinye zazo zihlobene nokusuleleka kunye nabanye abangenayo. Nangona kunjalo, enye yezizathu eziqhelekileyo ziyi-disorder bone disorder ye-hip eyaziwa njenge-avascular necrosis, okanye i-AVN.
Ukuqonda i-Avascular Necrosis
I-Avascular necrosis iyithambo kunye nesifo se-vascular esibonakalayo ngokuphindaphindiweyo kubantu abanentsholongwane kaGawulayo. Eyaziwa nangokuthi i- osteonecrosis , i-AVN yintlobo yesithambo sesifo sokufa okubangelwa ukunikezelwa kwegazi kumathambo. Ukugeleza kwegazi kugxininiswe ngenye yeendlela ezimbini: ngokunciphisa imithana yegazi okanye ukuxakeka kwiimpahla ezenza ithambo.
Njengoko ukuhamba kwegazi kuyancipha, iiseli ziqala ukufa ngenxa yokuntuleka kokutya. Njengoko imeko ibuhlungu, ithambo liba buthakathaka kwaye libuhlungu ngakumbi, ekugqibeleni, liba lungekho kakuhle kangangokuthi liphuka, ngokuphindaphindiweyo libe ngamaqhezu ambalwa.
I-AVN sisifo esiqhubekayo esibuhlungu ngaphezu kwexesha. Iphantse ihlala ichaphazela i-hip kodwa ingabonakala nasemadolweni okanye emahlombe. I-AVN ichaphazela abantu abane-HIV ngamaxesha angama-58 izinga elibonwe kubemi lilonke kwaye lidibaniswe, ubuncinci inxalenye, nokuvuvukala okungapheliyo okuhamba nosuleleko lwe-HIV olude.
Iimpawu kunye nokuxilongwa kwe-AVN
Kwimigangatho yokuqala ye-AVN, kunokubakho ambalwa okanye akukho mpawu. Njengoko eso sifo siyaqhubeka, kukho intlungu eqhubekayo kwi-groin kunye ne-hip. Njengoko i-AVN ingabonakali kwi-X-ray eqhelekileyo, ukuxilongwa kunokuba nzima. Enyanisweni, ngokuqhelekileyo iphosakele ngenxa yentlungu elula yomzimba okanye i- arthritis .
Ngaphandle kokuba i-scan IRM (i-MRI) ifunyenwe, i-AVN inokuhlala ingafunyanwanga iminyaka. Ekugqibeleni, intlungu ingakwazi ukunyamekela ukuba ukuhamba kuhamba. Iziqhekeza ziyaxhaphaka njengoko ukwanda kweethambo kuqala ukufa, ngokukodwa kwizihlanganisi ezinzima.
Izizathu ze-AVN kubantu abane-HIV
I-AVN yinkathazo eqhelekileyo kubantu abanentsholongwane kaGawulayo kwaye isoloko ixhamene nokuvuvukala okuqhubekayo kubonwe nosuleleko lwexesha elide. Ngethuba lexesha, ukuvutha kukubangela ukuphazamiseka kweeseli kunye nezicubu kuwo wonke umzimba, kubangele inkqubo yokuvelisa i-genetic ebizwa ngokuthi yi- senescence yangaphambi kwesikhathi (ukuguga kwangaphambili). Ngamanye amaxesha izazinzulu zibhekisela ekuphenduleni okuvuthayo njengokuthi "ukuvuvukala."
Njengomphumo wale nqubo, umntu onentsholongwane kaGawulayo uya kuba namava anxulumene nokuguga kwiminyaka eyi-10 ukuya kwe-15 ngaphambili ngaphambili kohlobo lwabangenayo. Phakathi kwezi meko ezinxulumene nokuguga i-bone and hip fractures ibonakala kubantu abangama-70 nangaphezulu.
Ezinye izinto ezinobungozi zingabangela i-AVN kubantu abane-HIV, kuquka:
- Ukutshaya
- Ukusetyenziswa kakubi kotywala
- I-cholesterol ephezulu kunye ne-triglycerides
- I-pancreatitis engapheliyo
- I-Coagulopathy (i-disorder disorder ebangelwa ukungakwazi ukuvala i-clot)
- Ukusetyenziswa kweCorostosteroid
Unyango lwe-AVN
Ngelishwa, akukho nonyango olungaphilisa i-AVN. Iimvumi zonyango kunye neengxaki ezingenayo i-narcotic zingasetyenziselwa ukukhulula intlungu. Amachiza anciphisa ukuvuvukala kwendawo anokunceda.
Kukho iinkqubo zokuphanda ezinokubuyisela ukuhamba kwegazi kwindawo echaphazelekayo. Nangona kunjalo, kwiimeko ezininzi, ukutshintshwa kwe-hip yindlela ephela yokubuyela ngokutsha xa kuthe kwafa.
Xa kuthethwa oko, ukuxilongwa kwangaphambili kunye nonyango lwe-HIV kuyaziwa ukunciphisa impembelelo yokuvuvukala okungapheliyo, ukunciphisa umngcipheko lwezifo ezininzi zangexesha elide ngama- 53 ekhulwini .
ILizwi
Ukuba unentsholongwane kaGawulayo kwaye ufumana intlungu okanye i-groin pain, xelela ugqirha wakho kungakhathaliseki ubunzima. Ukuxilongwa kwangaphambili kwe-AVN kukunika ukhetho oluninzi lwezonyango, ingaba ugqirha okanye awukho = uphenyo, kwaye unokuphucula umphumo wexesha elide ngelixa ugcina ukuhamba kwakho.
> Imithombo:
> ISIGABA SOKUQALA IQela lokuFunda. "Ukuqaliswa kweNtsholongwane kaGawulayo kwi-Antiretroviral Infection." I-New England Journal of Medicine. Julayi 20, 2015; INGXELO: 10.1056 / NEJMoa1506816.
> Wilmes, D .; I-Docquier, P .; Belkhir, L. et al. "I-Avascular necrosis yeentloko zeentlobo zezilwanyana kwizigulane ezinegciwane lesifo sengculaza (1-HIV)." Umbhalo we-International AIDS Society. 2012; 15 (iSiza 4): 18325.