Inyuled hypertonic saline enye yeendlela zokwenza unyango olutsha lwe-cystic fibrosis (CF). Iqela labaphandi base-Australia bafumanisa iingenelo ze-hypertonic saline xa bebona ukuba abahamba nge-CF baneziphumo ezingcono kunabantu abaneCF abangakhange bafake. Abaphandi babekholelwa ukuba ukunyusa imfudu yamanzi yolwandle ngexesha lokutshiza kwakusisizathu sokuba abaqhubi be-surfers babeneentlobo zokuphefumula ezincinci kunabo bafana nabo, kwaye uvavanyo luqinisekisile ezo ziphumo.
Abaphandi bapapasha iziphumo zokufunda kwabo ngo-2006, kwaye ukususela ngelo xesha, i-hypertonic saline sele ikhona njengendlela yokonyango kubantu abaninzi abaneCF.
Yintoni i-Hypertonic Saline?
I-saline eqhelekileyo isisombululo samanzi esetyuwa esineengxube zetyuwa efanayo njengamanzi ethu omzimba. I-hypertonic saline nayiphi na isisombululo samanzi esetyuwa esinexinaniso enkulu yetyuwa kunokuba i-saline evamile, kwaye ngoko ke ixilisi enkulu yetyuwa kunamanzi ethu omzimba. Isisombululo sosawoti esiqhelekileyo ngu-0.9% ityuwa. I-hypertonic saline esebenzisa kwi-CF unyango ngu-7% ityuwa.
I-hypertonic saline ilawulwa kubantu abane-cystic fibrosis kabini imihla ngemihla.
Ingaba isebenza kanjani
Ukudluliselwa kwamanzi kunye naphandle kweeseli ngenkqubo ebizwa ngokuthi i- osmosis , apho i-fluids ne-concentrated flow concentrations zihamba ngaphaya kwe-membrane yeseli ukuze zidibanise kunye nama-fluids kunye ne-concentrated concentration. Ngokucacileyo, i-osmosis ithetha ukuba amanzi alandela ityuwa.
Ngonyango lweCF, umatshini obizwa nge- nebulizer aerosolizesisombululo se-hypertonic saline. Umnyuzi we-saline uyangxininiswa kwaye uhleli kwi-airways. Ngenxa yokuba i-hypertonic saline inexininiso enkulu yetyuwa kunamanzi aqhelekileyo, ithambisa amanzi kwiiseli ukuya kwindlela yokuhamba. Umxube wamanzi kunye ne-mucus eninzi e-airway, okwenza kube mncinci kwaye kulula ukukhwehlela okanye ukukhupha.
(Inkcazo yegosa yezokwelapha ukukhwehlela i-mucus.)
Uphando oluhlola ukusetyenziswa kwe-hypertonic saline kubantu abane-cystic fibrosis libonisa ukuba olu unyango lunokubangela ukuphuculwa okuncinci kumsebenzi wamapulmonari kunye nokuhlaselwa okuncinci okanye ukunciphisa. Nangona kunjalo, umphumo wonyango uhluka phakathi kwabantu, kwaye abanye abantu banokufumana uxolo ngakumbi kunokuba abanye.
Iziphumo ezimbi
I-hypertonic saline ayiyilisisi, kodwa ibangela ukuba utshintsho emzimbeni lunokuba nemiphumo embi. Abanye abantu basebenzisa i-hypertonic saline baye bafumana ukunyuka kokukhwehlela, intlungu yomzimba okanye intlungu yesifuba ebangelwa zizibilini zenyama.
Akunjalo i-saline nje yamanzi eTyuwa? Ngaba Ingenziwa Ekhaya?
Inombolo yetyuwa kufuneka ibe ngokuchanekileyo, kwaye oku kunzima ukufezekisa kwisisombululo sokwenza izinto. Okubaluleke ngakumbi, isisombululo kufuneka sibe yinyumba ukukhusela ukungenisa ibhaktheriya esongela ubomi kwi-airways.
Imithombo:
> Chesnutt MS, Prendergast TJ. Iingxaki zePulmonary. Ku: Papadakis MA, McPhee SJ, Rabow MW. eds. Uxilongo lwezoNyango kunye noNyango 2016 . New York, NY: McGraw-Hill; 2016.
Donaldson, SH, kunye al. "Ukucaciswa kweMucus kunye nomsebenzi wokuLungisa kwiCystic Fibrosis nge-Hypertonic Saline". 2006. I- New England Journal of Medicine 354 (3): 1848-1851. 4 Agasti 2008.