Umbuzo esivame ukucelwa ngawo: Ngaba kufuneka ndizithabathe iivithamini ngexesha lomhlaza? Umbuzo obaluleke kakhulu kubhekiselele kumanani amaninzi. Ngo-2008, kwaphawulwa kwiNcwadana ye-Clinical Oncology ephakathi kwama-64 no-81 ekhulwini lwegulane zegulane zasebenzisa i-vitamin okanye i-mineral supplement (ngokungafani nama-50 ekhulwini labantu) kwaye phakathi kwe-14 ne-32 ekhulwini laba bantu baqala ukuthatha izongezo emva kokuxilongwa komhlaza.
Impendulo elula kukuba: "Nguye kuphela onokuyiphendula loo mbuzo yi-oncologist yakho."
Impendulo engcono yile: "Buza i-oncologist yakho phambi kokuba uthathe naziphi na izongezo, kodwa khangela ezinye zeengcamango ezingezantsi-izizathu kunye nokuchasene-ukuze ukwazi ukuqonda kakuhle impendulo yakho ugqirha uze wenze isigqibo kunye kunye." Ungaze uthathe i-vitamin, i-mineral, okanye i-antioxidant supplement ngaphandle kokuqala ukubonisana nogqirha wakho njengoko oku kunokuba yingozi kwabanye abantu abanomdlavuza.
Eli nqaku lihlanganisa ezinye zeengozi kunye neenzuzo zezibonelelo, kodwa kubalulekile ukuqaphela izinto ezimbalwa. Kukho ezininzi iintlobo zomhlaza, kwaye nangomnye uhlobo lomhlaza kukho ukungafani kakhulu. Yongeza ukuba umntu ngamnye oyingqayizivele, kunye neempawu zomzimba kunye nezinye izimo zonyango, kwaye kulula ukubona ukuba kutheni into enokubonakala ngathi ngumbuzo onzima kakhulu.
Uluhlu lwamavithamini kunye neemaminerali ezifunekayo kwimpilo, kunye nolwahlulo lwezidakamizwa eziqhelekileyo zokutya, lunokufunyanwa ekupheleni kweli nqaku.
Izizathu Zakho I-Oncologist Yakho Ingancomeka Ukungathathi iiVithamini
Ukunxibelelana okuNokwenzeka kunye neNzuzo yeMpilo
Esinye sezizathu eziphambili ze-oncologists asinakucebisa ii-vitamin kunye ne-mineral supplements okanye iifomula zokuncibilikisa i-antioxidant formula kuba ziyakwazi ukulwa nemiphumo ye-chemotherapy okanye unyango lwe-radiation.
Ama-radicals amahhala emizimbeni yethu (eveliswe yizinto ezinjengokutshaya umsila, ukushiswa kwemitha kunye neenkqubo eziqhelekileyo zokusetyenziswa komzimba) zingonakalisa i-DNA kwiiseli zethu (umonakalo womonakalo onokubangela umdlavuza.) Lo monakalo ubizwa ngokuba "umonakalo owenzayo" kuba ukusabela kubandakanya oksijini. Ama-Antioxidants akhiqizwa ngamagumbi ethu kwaye atyathwa kwiidlo zethu zisebenza ngokunyanzelekisa ezi zinto zikhululekile kunye nokukhusela umonakalo we-oxidative; ngaloo ndlela ukukhusela iiseli. Ingcinga kukuba i-antioxidants inokukhusela iiseli zeomhlaza zingonakaliswe yi-chemotherapy kunye neyeza. Asifuni "ukukhusela" iiseli zomhlaza.
Kukho uphando oluthile, ngakumbi kubantu ababhema, apho abantu basebenzisa izilwanyana ezineziphumo ezibi kakhulu. Ucwaningo olwenziwa ngo-2008 lubonise ukuba i-vitamin C yokunciphisa iyancipha ukuphumelela kwe-chemotherapy ngama-30 ukuya kuma-70 ekhulwini kwi-leukemia kunye namaseli e-lymphoma kwi-laboratory. Ezinye iingcamango zibonisa ukuba i-vitamin C ephezulu i nokuba neenzuzo kubantu abaphathwa ngemhlaza-ubuncinci kwibar. Izifundo ezibhekisele kwiiseli zomhlaza zesifuba somntu kwilebhu ziye zafumanisa ukuba i-vitamin C inciphise ukusebenza kwe-tamoxifen. Kule zifundo kwakucingelwa ukuba i-vitamin C iphazamise i-apoptosis, oko kukuthi, ukufa kweseli, kumaseli omhlaza.
Eminye yengozi ingaba yinto engakumbi. Uphononongo luka-2007 lwezifundo ukususela ngo-1966 ukuya ku-2007 alufumananga ubungqina bokuthi izidakamizwa ze-antioxidant ziphazamise i-chemotherapy, kwaye abanye abaphandi bakholelwa ukuba ama-antioxidants angakunceda ukukhusela iiseli eziqhelekileyo ngaphandle kokuphazamisa ukuphumelela komhlaza wonyango. Olu hlalutyo luquka ukufundiswa ngokusebenzisa i- glutathione , i-vitamin A, i-vitamin C, i-vitamin E, i-ellagic acid, i-selenium, ne-beta-carotene kwaye iphetha ngokuthi i-antioxidants ingaphucula impendulo ye-tumor kunyango kunye nokusinda kwamazinga, ngaphezu kokunceda ukunyamezela izigulane unyango. Olunye uphononongo olusisigxina lwezifundo ezingama-33 lufumene ubungqina bokusebenzisa i-antioxidants kunye ne-chemotherapy kwabangela ukungcola okungaphantsi, okuye kwavumela abantu ukuba bazalise amayeza athile.
Ngaphandle kweso sifundo esithile esabonisa ukwanda kwenzakazo kulabo basebenzisa isongezelelo se-vitamin A. Olu hlalutyo luvavanya izifundo ngokusebenzisa i- N-acetylcysteine , i-vitamin E, i-selenium, i-L-carnitine, i- Coenzyme Q10 kunye ne-ellagic acid.
Ukusebenzisana namanye amayeza
Kukho imizekelo emininzi yokusebenzisana okunokwenzeka, kodwa umzekelo olula yiyo i-vitamin E inokunyusa umngcipheko wokuphapha abantu kubantu abathabatha igazi elincinci laseCoumadin.
Imithombo yeZilwanyana kunye neZongezelelo
Ngokuqhelekileyo, umgaqo wokufumana iivithamini kunye neemaminera ngexesha lotyando lomhlaza "kukutya kuqala." Kwaye sizathu esihle. Asinalo uphando oluninzi olubhekiselele ekusebenziseni i-antioxidants ngexesha lotyando lwemhlaza, kodwa ukusetyenziswa kwezi zongezelelo ngenjongo yokuthintela umdlavuza uye wabonisa ezinye iziphumo ezithandekayo. Ngokomzekelo, ukubona indlela yokutya ephezulu ye-beta-carotene idibene nomngcipheko omncinci wokuba nomdlavuza wamaphaphu, isifundo esikhulu esibhekisele ekusebenziseni i-beta-carotene isongezelelo safumanisa ukuba ingozi yomdlavuza wamaphaphu yenyuka. Ezifanayo zifumene nomhlaza wesibeletho, apho i-vitamin E yokutya idibene nayo inomngcipheko omncinci, kodwa isifundo sokuvavanya i-vitamin E isongezelelo sithole ingozi eyongeziweyo. Iingcamango zicetywayo ukuba zichaze oku. Mhlawumbi kukho iiprotochemicals (iikhemikhali ezisisityalo) ekutya ngaphandle kwe-beta-carotene enoxanduva lokukhusela umdlavuza. Enye ingcamango ephakanyisiwe kukuba ukufumana enye i-antioxidant njengesongezelelo kunokubangela ukuba umzimba uthathe ubuncinane okanye usebenzise ngaphantsi, omnye umntu obalulekile wokulwa ne-antioxidant.
Ngamanye amaxesha kuthatha i-supplement enye inkxalabo kunokuphakamisa enye inkxalabo. Umzekelo ufundiso apho abantu abane-melanoma baphathwa ngayo nge-selenium. Abaphandi bafumanisa ukuba isongezelelo sasinomngcipheko omncinci wokuvelisa umdlavuza wesibili kwimiphunga, i-colon, okanye iprotrate, kodwa nayo idibene nomngcipheko ophezulu we-diabetes.
Uninzi lwe-oncologists uncoma ukuba ukutya ukutya okunempilo kwaye ungakholelwa ukuba i-antioxidants etholakala ekutya ibeka ingozi ekunopheni imithi yokwelapha. Ukuba unqwenela ukwandisa ukutya kwakho kokutya kwe-antioxidants khangela ezo zokutya kunye nama-antioxidants amaninzi.
Indlela yoFundo
Ukutolika ezinye iinkcukacha kwi-antioxidants ngexesha lotyando lwemhlaza kunzima kwizizathu ezininzi, enye yezona ndlela ezahlukileyo ezisetyenziswayo. Ezinye izifundo zenziwa kwiigorants, kwaye iziphumo kwiigulane zinakho okanye zingenjalo nazo kubantu. Zininzi zezi zifundo zenziwe kwiiseli zomhlaza zomntu ezikhulile kwisitya kwilebhu. Nangona oku kusinika ulwazi olufanelekileyo, aluyi kuthathelwa ingqalelo kwiininzi zezinye iinkqubo eziqhubekayo emzimbeni womntu onokutshintsha impendulo ebonwe kwibha.
Izizathu Zakho I-Oncologist Yakho Ingancoma iiVithamini
Ukunqongophala kwezondlo
Ngenxa yeempembelelo zokulahleka kwesidlo kunye nesisongulu esifana nomdlavuza, ukungaphumeleli kwesondlo akuqhelekanga. Thetha ugqirha wakho ngale ndlela. Abanye abaphandi baye bathi i-supplementation inganceda ukunciphisa umlenze womhlaza womhlaza . I-Cachexia yintsholongwane yokulahlekelwa kwesisindo esingenakuzenzela, ukuchithwa kwemisipha kunye nokunciphisa ukutya okuchaphazela kuma-50 ekhulwini labantu abanomhlaza ophezulu. Kuvakalelwa kukuba i-cachexia igalela ngokuthe ngqo kwi-20 ekhulwini lomdlavuza womhlaza. Ngokudabukisayo, ngaphandle kweoli yeentlanzi ezinokukunceda, izongezelelo zondlo azifumaneki ekuncedeni kule syndrome.
Ukukhusela umdlavuza wesiBini
Ekubeni unyango lwezonyango ezifana ne-chemotherapy kunye neyeza zonyango ezixhomekeke kwiintsholongwane, kuye kwathemba ukuba umngcipheko wesibeleko wesibili ungancitshiswa kunye nokusetyenziswa kwe-antioxidant supplements. Njengoko kuphawuliwe ngasentla, kwiphando elithile abantu abane-melanoma ephathwa nge-selenium babenomngcipheko ophantsi wokuba nomdlavuza wamaphaphu, i-colon, okanye i-prostate (kodwa unomngcipheko ophezulu wesifo sikashukela.) Kanye njengoko izongezelelo (ngokuchasene ne-antioxidants) iziphumo ezingaguqukiyo zokuthintela umdlavuza, akukho ubungqina obuninzi bokuthi ezi zongezelelo ziya kuba luncedo ekukhuseleni umdlavuza wesibili kwabasindileyo.
Ukunciphisa Utyholongwane lweZonyango
Ucwaningo luxutywe malunga ne-antioxidants ekwandiseni okanye ukunciphisa utyhefu lwe-chemotherapy, kodwa uphando oluthile lubonisa ukuba lunokuphucula umgangatho wobomi kwabanye abantu ngexesha lotyando lomhlaza. Kwisifundo esithile, umxube we-antioxidant oqukethe i-vitamin C, i-vitamin E, i-melatonin kunye ne-extract tea itholakala ukunciphisa ukukhathala kubantu abanomdlavuza we-pancreatic.
Iziguli ezinomdlavuza ophezulu
Uphononongo olucatshulwe ngandlela-thile oluxhasa ukusetyenziswa kwe-vitamin supplements ngexesha lotyando lwemhlaza lubonisa ukwanda kwithuba lokusinda. Uphononongo luka-2009 lubonakalise ixesha elide kunokuba kulindeleke ukuba liphile ixesha elide, kunye ne-76% yezigulane zihlala ixesha elide kunokuba ziqikelelwe (ukwanda kwenani lokuphila kwiinyanga ezili-5.) Kubalulekile ukuba uqaphele ukuba lesi sifundo sincinci (izigulane ezingama-41) eziqhutywe abantu bacinga ukuba banomdlavuza wokuphela kwesigaba esinexesha elilindelekileyo lobomi beenyanga ezili-12 kuphela. Ezi zi gulane zanikwa unyango lwe-coenzyme Q10, iivithamini A, C, no-E, i-selenium, i-folic acid, kunye nabangenayo umdlavuza wamaphaphu, beta-carotene.
Icandelo elikhethekileyo leVithamini D kunye neCarcer
Ngezizathu ezininzi, i-vitamin D ifaneleke ingqalelo ngokukhethekileyo malunga nendima yayo kwonyango lomhlaza.
Isizathu sokuqala kukuba kunokuba nzima ukufumana inani elaneleyo le-vitamin D ngamanyathelo okutya. Nangona isibonelelo samhla ngemihla esinconywayo singama-400 ukuya ku-800 kwi-IU ngokuxhomekeke kwiminyaka yobudala, uphando olujongene nokuthintela umdlavuza luye lwajonga amaninzi aphezulu-ukuya ku-1000 ukuya ku-2000 kwi-IU ngosuku. Siyicinga ngobisi oluqinileyo njengomthombo we-vitamin D, kodwa kwi-galasi ye-100 ye-IU kufuneka ifune ukusela 8 iiglasi ngosuku ukufikelela kwi-800 ye-UU eyayinconywe ngomntu oneminyaka engama-70 ubudala okanye ibhinqa kwizifundo zokuthintela umdlavuza.) Ilanga ngumthombo omuhle we-vitamin D, efuna kuphela ixesha elifutshane nje ngeengalo kunye nobuso obuvelele ukufumana ngaphezulu kwe-5000 IU. Okokuthi, ukuba uhlala kwindawo apho ungabikho ngaphandle kunye neengalo zakho kunye nobuso obonakalayo kwaye ukuba i-angle yelanga kwindawo yakho ivumela ukuxhamla imitha ye-vitamin D.
Oku kunokuba yingxaki kwiindawo ezisemantla.
Ngenxa yoko, abaninzi oogqirha bancomela ukuxhaswa kwe-vitamin D3. Ngubani omele athathe isongezelelo? Ngombulelo ugqirha wakho unendlela elula yokumisela oku. Ukuhlolwa kwegazi okulula kunye nokungabizi kunokukunika wena kunye nogqirha wakho ngomlinganiselo wegazi lakho levithamini D (kunoko, iimveliso zomzimba eziphazamisayo). Ngoxa le nto ayiyi kukuxelela ukuba umzimba wakho ogciniweyo "ugcino" we-vitamin D, ungasetyenziselwa ukuchonga ukuba kufuneka uncedo kunye nokukhokela unyango. Gcina ukhumbule ukuba uninzi lwabantu baseUnited States bafumana i-vitamin D.
Kutheni oku kubalulekile?
Kukho ezininzi izifundo eziye zavavanya indima ye-vitamin D kokubili ekukhuselweni komhlaza nangokwelashwa komhlaza. Amanqanaba aphantsi egazini le-vitamin D anxulumene nobungozi obuninzi beekliniki ezininzi, kunye nezinga eliphezulu le-vitamin D lidibene nomngcipheko ophantsi wokuphucula umbele kunye nomdlavuza. Abantu abanamazinga aphezulu e-vitamin D ngexesha lokuxilongwa banamaqondo okuphila okusasazeka kumdlavuza wamaphaphu kunabo abanamaqondo aphantsi. Kwaye, ngokuphathelele umbuzo wethu ngokuphathelele ukusebenzisa iivithamini ngexesha lotyando lomhlaza, amazinga aphantsi e-vitamin D abonakala ephakamisa umngcipheko wokusabalalisa umdlavuza webele. Mhlawumbi umphumo obalaseleyo uye wabonakala ngomhlaza wekolon. Uphando olutsha lweSizwe weCancercer Institute lufumene ukuba abantu abanamazinga aphezulu e-vitamin D babengama-76 ekhulwini abangaphantsi kokufa ngenxa yesifo sabo kunabantu abanamaqondo amancinane evithamini.
Ekubeni ezinye zonyango zonyango zixhomekeke kwi-osteoporosis, kwaye i-vitamin D ixhasayo i-calcium absorption, inqanaba elaneleyo le-vitamin D linokuchaphazela umgangatho wobomi kwezinye izigulane zomhlaza.
I-Vitamin D ayiyiyo i-antioxidant. Ngokwenene isebenza ngokufana nehomoni kunevithamini emzimbeni.
Nangona uphando oluninzi lubonisa indima enobomi be-vitamin D ubuncinane kwabanye abantu abanomdlavuza, kubaluleke kakhulu ukuthetha nodokotela wakho ngaphambi kokusebenzisa isongezelelo. Enyanisweni, ugqirha wakho uya kufuna ukubeka iliso kumanqanaba akho ukuba abone ukuba atshintshe xa uqala isongezelelo. Uhlobo oluqhelekileyo lwexabiso lungaba luluhlu olufanelekileyo lomntu onomdlavuza. Ngokomzekelo, kwi-Clinical Mayo eMinnesota, uluhlu oluqhelekileyo lwamanqanaba e-vitamin D lu-30-80. Nangona uphando oluthile lubonisa ukuba izinga le-50 libhetele kunezinga le-31.
Ukuxhaswa kwe-Vitamin D akuyena wonke umntu. Kukho iziphumo ezichaphazelekayo ezibandakanya iintlungu zepilisi-ukuba amazinga aphezulu kakhulu.
Ukuthatha i-Vitamin okanye isongezelelo ekhuthazwa nguDokotela wakho
Ukuba i-oncologist yakho iphakamisa ukuxhaswa, kukho izinto ezimbalwa zokugcina engqondweni.
- Kwakhona. Sebenzisa kuphela amavithamini okanye amaminerali (okanye nayiphi na enye isondlo okanye izithako ezongezelelweyo) xa i-oncologist yakho ingacingi ukuba le nto ingalimaza kwimeko ethile.
- Ubungozi obuhle kunye neenzuzo ezikhankanywe ngasentla kuphela nje ukubonisa ukuba kutheni iivithamini kunye nezongezelelo zamaminerali kufuneka ziqwalaselwe ngabanye kumntu ngamnye. Ugqirha wakho unokucetyisa ukusebenzisa okanye ukuphepha i-vitamin okanye i-mineral supplements ngezizathu ezongezelelweyo.
- Njalo uzisa iipilisi zonke kunye neepilisi kunye nawe kwi-aphocology ukuqeshwa.
- Musa ukukhohliswa ngentengiso ethi "yendalo" okanye "isityalo esekelwe." Umzekelo u-hemlock. Kuyinto yemvelo, isityalo esekelwe kuyo, kwaye sinokukhula ngokwaneleyo. Sekunjalo becingelwa ngabaninzi ukuba kwakuyi-poison ebizwa ngo- Romeo noJuliet . Enyanisweni, ezininzi izidakamizwa ezinamandla ezinokhemotherapy zithe zityalo.
- Sebenzisa kuphela i dose ephakanyisiweyo. Okungakumbi akunakulungile kwaye kunokuyingozi. Gcina ukhumbule ukuba iziqhamo zihlala ziqukethe amanqanaba amavithamini kunye neemaminerali ezigqithiseleyo kunokuba uza kudla ukutya okuqhelekileyo. Ukongezelela, kukho umgaqo omncinci walezi zongezelelo eUnited States, kwaye ezinye iimveliso zineenkcukacha zezilwanyana ezibulala izibulala neensimbi ezinzima.
- Sebenzisa kuphela iivithamini kunye namaminerali amgangatho. Khangela ukujonga ukuba ngaba bavavanywa nguCommunityLab.com. Khangela kwakhona ukuba ukhangele ukuba kukho i-USP okanye iNF seal kwilebula, ebonisa ukuba uvavanyo lokulawula umgangatho lwenziwe kwimveliso.
- Qhubeka uxoxisana nokutya kwakho kwamavithamini kunye neemaminerali ekutyelelweni kokulandelelana. Uninzi lwezilingo zekliniki ziyaqhubeka, kwaye ulwazi lunokutshintsha-nakulo naluphi na ulwalathiso-njengoko sifunda ngakumbi.
Ukuhlaziywa kwamaVithamini kunye neMaminerali
AmaVithamini Amalungu ethu adinga:
- IVithamini A
- I-Vitamin B6 (i-pantothenic acid)
- I-Vitamin B12 (i-biotin)
- Vitamin D
- Vitamin E
- Vitamin K
- Ifolic acid
- Niacin
- Riboflavin
- Thiamine
Amaminerali Amalungu ethu adinga:
- ICalcium
- Chromium
- ICopper
- Iodine
- Intsimbi
- IManganese
- Magnesium
- Potassium
- Selenium
- Sodium
- Zinc
Antioxidants:
I-Antioxidants ingaba ngamavithamini, amaminerali, okanye ezinye izondlo. Imizekelo yalezi ziquka:
- IVithamini A
- Vitamin C
- Vitamin E
- Selenium
- I-Carotenoids - i-beta-carotene kunye ne-lycopene
> Imithombo:
I-American Society ye-Clinical Oncology. I-Cancer.net Iingcebiso ngeZondlo ngexesha kunye nangemva kokunyanga kweCercer. 03/2014.
Vimba, K., Koch, A., Mead, M., Tothy, P., Newman, R., kunye noCyllenhaal. Impembelelo yokuxhaswa kwe-antioxidant kwi-chemotherapeutic esebenzayo: uhlaziyo oluchanekileyo lobungqina obuvela kwizilingo ezilawulwa ngononophelo. Uphononongo lweZonyango . 2007. 33 (5): 407-18.
UDenner, uG., noMn. Horneber. I-Selenium yokuxhoma imiphumo emibi yekhemotherapy, i-radiotherapy, kunye nokuhlinzwa kwabaguli. Library Cochrane . Ukuhlaziywa 02/16/09. INGXELO: 10.1002 / 14651858.CD005077.pub2
UGreenlee, H., uHershman, D., noJacobsonson. Ukusetyenziswa kwee-antioxidant supplements ngexesha lotyando lomhlaza webele: uhlolo olubanzi. Uphando lwe-Cancer noPhando . 2009. 115 (3): 437-52.
UHeaney, M., Gardner, J., Karasavvas, N., Golde, D., Scheinberg, D., Smith, E., no-O. O'Connor. I-Vitamin C ixhathisa ingozi ye-cytotoxic yezilwanyana ezixhamlayo. Uphando lweCancer . 2008. 68 (19): 8031-8.
Hertz, N., no R. Rister. Ukuphucula ukuphulukiswa kwizigulane ngeCoststage Cancer Eqhutywe kunye neCoenzyme Q10 kunye nezinye i-Antioxidants: iSifundo seSifundo. I-International Journal Yophando Lophando . 2009. 37: 1961-7 1.
Lawenda, B., Kelly, K., Ladas, E., uSagar, S., Vickers, A., kunye noJlumberg. Ngaba ulawulo lokuxhatshazwa kwe-antioxidant kufuneka lukhutshwe ngexesha lohlobo lwe-chemotherapy kunye nokwelashwa kwamayeza? . Umbhalo weNational Cancer Institute . 2008. 100 (11): 773-83.
National Cancer Institute. Antioxidants and Prevention Cancer. Ukuhlaziywa 01/16/14.
National Cancer Institute. I-Vitamin C ephezulu kakhulu (i-PDQ). Updated 04/08/15.
Peralta, E., Viegas, M., Louis, S., Engle, D., noG. Dunnington. Umphumo we-vitamin E kumaseli omhlaza webele we-tamoxifen. Ukuhlinzwa . 140 (4): 607-14.
Subramani, T., Yeap, S., Ho, W., Ho, C., Omar, A., Aziz, S., Rahman, N., noM M. Alitheen. I-Vitamin C igxininisa ukufa kwe-cell kwi-MCF-7 yeseli yesifo somhlaza wesisu esenziwa ngumthamo we-tamoxifen I- Journal ye-Cellular and Molecular Medicine . 2014. 18 (2): 305-13.
Velicer, C., noC. Ulrich. Umbuzo obalulekileyo kakhulu I-Vitamin kunye ne-Mineral Supplement Usetyenziso phakathi kwabantu abadala base-US Emva kokuxilongwa kweCcercer: UkuHlola kwakhona. Umbhalo we-Clinical Oncology . 26 (4): 665-673.