Yintoni ebangela ukukhathazeka okuZenzekelayo kwaye Ziyakuthathwa njani?
I-Psoriasis ibangela iimpawu ezahlukahlukeneyo ezibangelwa ukucaphukisa nje. Iimpawu zingabandakanya iintambo ezibomvu, ezibomvu kwesikhumba; zifakwe, zigqitywe ngomunwe; i-scaly, i-scalp kunye nelahleko; kunye nezintlu, ezibuhlungu.
Kutheni abanye abantu, kodwa kungekhona abanye, bafumana le nto ephazamisayo kwindawo yokuqala? Ukufika kwimpendulo yalo mbuzo uxhomekeke kwinqanaba ekukwazi ukuba i-psoriasis yintlupheko yokuzimela- "auto" ithetha ukuba yedwa kunye "nokuzivikela" ngokubhekiselele kumzimba womzimba omzimba onzima.
Yintoni i-Disimune Disorder?
Umzimba wakho womzimba unoxanduva lokulwa nabahlaseli bamanye amazwe besongela impilo yakho: iibhaktheriya, iintsholongwane kunye nefungi ziyimibandela embalwa nje. Impilo yakho enhle ixhomekeke kwizinto ezimbini ezibalulekileyo zesistim somzimba:
- Amasosha omzimba wakho kufuneka akwazi ukuqonda zonke iisculi kunye nezitho zomzimba wakho njenge "uqobo" kwaye ngoko ungazihlaseli.
- Amasosha omzimba wakho kufuneka akwazi ukubona abahlaseli bamanye amazwe njenge "ezinye" ukuzilwela.
Ngelishwa, xa unesifo sokuzimela, umzimba wakho we-immune udibanisa ngephutha "into" yinto "enye." Esikhundleni sokukhusela umzimba wakho, isimiso somzimba sokuzivikela sisenza iiseli kunye neekhemikhali ezihlasela umzimba wakho, ezibangela ukulimala nezifo.
Kukho izifo ezininzi ezihlukeneyo, ezibandakanya i-psoriasis, i-rheumatoid arthritis, ezinye iintlobo zezifo ze-thyroid, ezinye iindidi ze-anemia, i- lupus , i- celiac nezifo ze- diabetes .
Kutheni i-Psoriasis i-Autoimmune Disorder?
Njengengxenye yokhuselo lwayo kumazwe angaphandle, umzimba wakho wenza amaseli egazi amhlophe abizwa ngokuba yi-T-seli. Kwiimeko eziqhelekileyo, i-T-cell ichonga kwaye iququzelele ukuhlaselwa kwabahlaseli bamanye amazwe.
Nangona kunjalo, xa unesi-psoriasis, i-T-cell yakho ichane ngokuchanekileyo iiseli zeekhumba lakho njengabahlaseli kwaye zihlasela.
Olu hlaselo lulimaza iiseli zesikhumba, lubeka i-cascade yeempendulo kwisistim somzimba wakho somzimba kunye nasesikhumbeni sakho, okubangele umonakalo wesikhumba obonwe kwi-psoriasis-ukukhukhuma, ukuvuvukala, nokukhawuleka.
Ngomgudu wokuphilisa, iiseli zakho zesikhumba ziqala ukuvelisa ngokukhawuleza ngaphezu kokuqhelekileyo, kwaye iininzi zamaseli amatsha ekhumba zinyusa indlela ephezulu kwesikhumba sakho. Oku kwenzeka ngokukhawuleza kangangokuba amaseli asekhulile kunye neeseli ezimhlophe zegazi azichithanga ngokukhawuleza. La maseli alahliwe aqokelele phezulu kwesikhumba, ekwakheni izibonda ezibomvu, ezibomvu kunye nezikali zesigcawu ebusweni bawo: uphawu olukwi-classic ye-plaque psoriasis.
Kutheni Abantu Benza I-Psoriasis?
Zomibini izinto zendalo kunye neendawo zendalo zikholelwa ukuba zinoxanduva lokuba ngaba umntu akayi kufumana i-psoriasis okanye akukho. Iingcamango kukuba abo bahlakulela eso sifo bazalwa kunye nokwenza imfuza ethile eyenza ubungozi be-psoriasis, kwaye abo bahlakulela isifo eso bavelele kwimeko ethile ebangela ukugula.
Ukudibanisa ezinye izinto ezikhuselekileyo zendalo zibonakala ziqala ukuqala umatshini womzimba womzimba kubantu abasengozini. Ezinye zezinto ezingqongileyo ezibonakala ngathi zinokubangela i-psoriasis okanye ukudala ukutshatyalaliswa kwimeko kumntu osuvele ene-disorder iquka:
- Izifo. I-Psoriasis idla ngokuqala okanye ibuhlungu emva kokuba unesifo esithile, ikakhulukazi esibangelwa yi-streptococcus bactteria (njengokuba "kwi- strep throat ").
- Mayeza. Izidakamizwa zeLithium, i-anti-malaria, imishanguzo ephezulu yegazi (ebizwa ngokuthi "i-beta blockers") kunye nezidakamizwa ezichasayo i-Indocin (i-indomethacin) ezinye zeziyobisi ezibonakala ngathi zinokubangela.
- Ukulimala kwesikhumba. Ikhumba elomileyo, ukutshisa ilanga, ukusika, kunye nemijelo ngamanye amaxesha kukhokelela kwi-psoriasis.
- Ukuxinezeleka. Ezinye iingcaphephe zibonisa ukuba uxinzelelo lunokuthi lube yintambo ye psoriasis.
Iingxaki ze-Autoimmune zithathwa njani?
Inani lamachiza lingasetyenziselwa ukuzama ukuhlalisa isistim somzimba.
Imizekelo emibini eqhelekileyo yiT trexall (methotrexate) kunye neSandimune (cyclosporine). Olunye unyango olunokwenzeka luseklasini ebizwa ngokuba yi "biologic drugs", eyenziwa kwiprotheni yabantu okanye yezilwanyana, kuquka i-Enbrel (etanercept), i-Remicade (infliximab) kunye ne-Humira (adalimumab).
> Imithombo:
> Ferri, FF "Psoriasis." Umcebisi weCliniki kaFerri 2008 . 2008. Habif, TP "I-Psoriasis kunye nezinye > iiPapulsquamous > Izifo." Dermatological Clinic . 2004.
> Lowes, MA "Iingcamango zangoku kwi-Immunopathogenesis ye-Psoriasis." Iikliniki zeDermatological. 22 (2004): 349-69.
> Luba, KM "Chronic Plaque Psoriasis." WaseMerika ugqirha . 73 (2006): 636-44.
> "I-Psoriasis." aad.org . 2007. I-American Academy yeDermatology. 23 uJuni 2008.
> Shaw, JC "I-Psoriasis kunye nezinye izifo zePapulosquamous". Incwadi Yonyango Lwempilo Yonyango . 2001.