Yintoni abantu abanesifo sesifo sikashukela esifanele bazi ngeMetformin

I-Metformin (amagama e-brand Fortamet, i-Glucophage, i-Glumteza, i-Glucophage XR, i-Riomet) yonyango lomlomo elisetyenziswe yedwa okanye namanye amayeza ukuphatha uhlobo lwesifo sikashukela. Kwaye kwavunyelwa i-FDA ngo-1994 kwaye ikhona njengento yokudibanisa i-rosiglitazone / metformin (i-Avandamet).

IiDos neDont

I-Metformin inceda isishukela segazi ngeendlela ezintathu:

1. Linciphisa inani le-glucose elibanjwe ekudleni.

1. Linciphisa inani le-glucose eveliswe sisibindi.
2. Ukwandisa impendulo yomzimba kwi-insulin.

I-Metformin ayinciphisi ngokukhawuleza ushukela wegazi njengoko i-insulin yenza. Ngenxa yoko, akufanelekanga kwizigulane ezine-type 1 zeswekile zingafaki i-insulin.

Ngubani ongafanelanga ukuyisebenzisa

Abantu abane-type 1 (i-insulin-dependent-dependent) yesifo sikashukela, isifo sesifo , okanye ukuhluleka kwezintso akufanele ukuyisebenzise. Akunabantwana abaneminyaka engaphantsi kwe-10 ubudala. Abantwana abangaphantsi kweminyaka eyi-17 abafanelekanga ukusebenzisa ukulungiswa kokukhululwa kwe-metformin.

Isistim

I-Metformin ithathwa kabini ngosuku, mhlawumbi ngokutya. Ukuba idilesi ilahlekile, ipilisi ephosakeleyo imele ithathwe ngokukhawuleza, ngaphandle kokuba iphantse ifikelele kwimizuzu elandelayo. "Ukuxolisa" kumayeza ukuze wenze i dose ephosakeleyo akufanele kwenziwe.

Iimpawu eziPhakathi kunye neengozi

I-Metformin ibangela ukuba isifo sohudo xa sithathwa ngaphandle kokutya. Ezinye iziphumo ezichaphazelekayo ziquka ukuguqulwa kwesisu, igesi kunye nokuqhaqha, ukunambitheka kwentsimbi, intloko, ukukhwehlela, kunye nentlungu yomzimba.

Ukuba i-metformin ayinelisekanga ukulawulwa kweswekile, izigulane ezithatha i-metformin zinokufumana ishukela ephezulu yegazi , kunye neempawu zokudideka, ukuthatha umlomo, umlomo owomileyo, ukuhlanza, ukuphefumula okomnandi, okanye ukulahleka kwengqondo. Nabani na ofumana nayiphi na le mpawu-okanye intlungu yesifuba, ukukhawuleza, okanye ezinye iimpawu ezibuhlungu-kufuneka zifune unyango olusisiseko.

Ngokuqhelekileyo, i-metformin ingabangela i-lactic acidosis, imeko enzulu ebonakalayo yenziwe nge-lactic acid egazini. I-Lactic acidosis, ukuba ingaphathiswa, ingakhokelela ekuphumeleleni komzimba kunye nokuboshwa kwenyama. Iimpawu ziquka ukukhathala, ubuthathaka, ubuhlungu beentlungu, ukuphefumula okufutshane, kunye nokukhanya.

Nangona kunqabile xa kungekho zinkxwaleko zonyango, i-drug overdoses okanye ukusebenzisana kwezidakamizwa, i-metformin inokubangela ishukela ephantsi yegazi (u-hypoglycemia), ebonakaliswa ukuxakeka, ukuchithwa, ukuxubha, ukudideka, okanye ukugubungela emlonyeni.

Ukusetyenziswa kweTekisi

I-Metformin ingasetyenziselwa ngaphandle-ileyile ukuncedisa ukulahleka kwesisindo, i-polycystic syndrome, isifo sikashukela nesifo se-HIV lipodystrophy syndrome.

Iingcebiso kunye nokuqapha

Abantu abanesifo sikashukela kufuneka balandele ukutya okunempilo kunye neenkqubo zokuzilolonga njengoko kunconywe ngababoneleli babo bezempilo. Isidlo akufanele sithwetshwe kwaye ukusela utywala kufuneka kugwenywe.

Imishanguzo emitsha kunye neyeza-anti-counter-medication akufanele ithatyathwe ngaphandle kwemvume yonyango lobugcisa. Ukongeza, abantu abanesifo sikashukela kufuneka bahlolisise rhoqo ukuba bahlole isifo sikashukela, kuquka iimvavanyo zegazi ukujonga isimo sabo seshukela sexesha elide (HbA1c).

I-Metformin kufuneka ishiywe kwiiyure ezingama-48 ngaphambi kokuba nawaphi amazinyo okanye iinkqubo zokugqirha kwaye ngaphambi kokufumana ukungafani okungafaniyo (oko kukuthi i-CT scans). Kubalulekile ukuba abantu be-metformin baxelele ababoneleli bezempilo ukuba bayithathe.

_Imithombo:

_{"I-Metformin: Ulwazi lweziyobisi." Phezulu kwi-Intanethi kwi-2007. UpToDate.}

_{"I-Metformin: Ulwazi lwezonyango." UpToDate Online. 2007. UpToDate.}

_{"I-GlaxoSmithKline Izisa i-FDA imvume kunye nokuqaliswa kwe-Avandamet® (i-rosiglitazone i-HCl kunye ne-metformin HCl) njengeTraal Initial kwi-Treatment of Type 2 Diabetes." GlaxoSmithKline. 11 Julayi 2006. GlaxoSmithKline.}

_{"Metformin." Iinkcukacha zeDrink Plus. 1 kuMeyi 2007. ILebhu yeSizwe yeMatriki ka-US.}