Isifo sesisu, esibizwa ngokuba yi-myopathy, sinokuvela ngenxa yokuba ne-thyroid engasebenzi (ebizwa ngokuba yi-hypothyroidism) okanye i-thyroid engasebenzi (ebizwa ngokuba yi-hyperthyroidism).
Iindaba ezilungileyo kukuba iimpawu ze-myopathies ezinxulumene ne-thyroid, ezinjengeentlungu zomzimba, ubuthathaka, okanye ubunzima, ngokuqhelekileyo zilula kwaye zinyanzeliswe ngonyango olukhawulezayo lwe-thyroid disorder. Oko kwathiwa, kwiimeko ezingaphantsi kangangoko, i-myopathy yomntu ehambelana nezifo ze-thyroid ingaba nzima kwaye iyancipha.
Ngokufumana ukuqonda okungcono impawu ze-muscle zesifo se-thyroid (kunye nendlela abaya kufumana ngayo kwaye baphathwe ngugqirha wakho), unokuqiniseka ukuba ufike kumgangatho ongathandekiyo kunye / okanye ubuthathaka.
Hypothyroid Myopathy
Iimpawu
Ubuthakathaka obuthathaka, ama-aches, kunye ne-cramping ziqhelekileyo kubantu abane-hypothyroidism. Ngelixa ubuthathaka buya kuba yinto eqhelekileyo, abantu bayayifumana kwiimisipha ezikufutshane nakwiziko lemizimba yabo, njengentambo okanye ihlombe . Oku kunokukhokelela kwiingxaki eziphakama izitebhisi okanye udibanise iinwele zakho.
Ukongeza kwiimpawu ze-muscle, umntu unokuba ne-creatinine kinase (CK) ephakamileyo ekuhlolweni kwegazi. I-Creatinine kinase iyi-enzyme ye-muscle eyenyuka ngengozi yomzimba. Kuyathakazelisa, inqanaba le-CK alinakuqhagamshelanisa ubunzima beentlungu zomntu.
Ngokuqhelekileyo, ukubonakaliswa kwemisipha ebonakalayo kwi-hypothyroidism inokuphuhliswa. Omnye umzekelo ngu-Hoffman's syndrome apho umntu ehlakulela i-hypertrophy (imisindo ekhulisiweyo) eyabangela ukuqina komzimba, ubuthathaka kunye nentlungu.
I-Rhabdomyolysis (xa i-muscle iphuka ngokukhawuleza) yinto enye engabonakaliyo ye-muscular manifestation ye-hypothyroidism. Ngokuqhelekileyo kubangelwa ukudibanisa kwe-hypothyroid ngokuzivocavoca ngamandla okanye ukuthatha umgangatho (i-cholesterol-downing medication).
Isizathu
Nangona iimeko ezichanekileyo ze-hypothyroidism-ezibangelwa i-myopathy ayengacacanga, ezinye iingcali zicinga ukuba i-thyroxine (T4) yokuntuleka kwezinto ezibonakalayo kwi-hypothyroidism ikhokelela kwisifo se-metabolism esingaqhelekanga, ekugqibeleni kubangela ukulimala komzimba kunye nokukhubazeka kwemisipha.
Ukuxilongwa
Ukuxilongwa kwe-hypothyroidism-eyenziwa yi-kyoyiyo yonyango, oku kuthetha ukuba ugqirha uya kuluxilonga ngokusekelwe kwiimpawu zakho kunye nokuhlolwa komzimba. Ukuhlolwa kwegazi ukulinganisa i-creinine kinase kuya kwenziwa.
Ugqirha wakho unokuncoma ezinye iimvavanyo, njenge-electromyography okanye i-biopsy muscle, ukulawula ezinye iimeko, ingakumbi ukuba iimpawu zakho zinzima.
Unyango
Qinisekisa ukuba i-hormone ye-thyroid yokutshintshwa nge- Synthroid (levothyroxine) isenokukwazi ukuphucula iimpawu ze-muscle, njengezinqatha kunye nokuqina, nangona oku kuphucula kuthatha iiveki. Ubuthakathaka obuthathaka obuthathaka buhlala kuthatha ixesha elide ukulungisa, njengeenyanga ezininzi.
Hyperthyroid Myopathy
Iimpawu
Ubuthakathaka obuthathaka bungakhula kubantu abane-hyperthyroidism. Ngenxa yobuthathaka, umntu unokufumana ubunzima ukunyuka izitebhisi, ukunyuka esihlalweni, ukubamba okanye ukuthatha izinto, aze afinyelele iingalo zawo ngaphezu kwentloko. Ngokuqhelekileyo, kwi-myopathy evela kwi- hyperthyroidism , izihlunu ezichaphazelekayo zingaquka ezo zikunceda ukugwinya nokuphefumula.
Kuyathakazelisa, nangona i-cramps kunye ne-aches i-muscle iyenzeka, ayifani ngokuqhelekileyo njengoko i-myopathy ehlobene ne-hypothyroidism.
Inqanaba le-creatinine kinase egazini ngokuqhelekileyo liqhelekile, nangona kunjalo, kukho ukulahleka kwemisipha.
Njengawe-hypothyroidism-eyenziwa yindlela yokukhupha i-myopathy, inani alihambelani kunye nobukhulu bempawu zomzimba zomzimba.
Isizathu
Njengesifo se-muscle kwi-hypothyroidism, "kutheni" emva kwe- myopathy kwi-hyperthyroidism ayibonakali. Kungenzeka ukuba izinga eliphakamileyo lamahomoni e-thyroid emzimbeni ligalelo ngqo. Ngokukodwa, ezi ziphezulu ze-hormone ye-thyroid zingakhokelela ekwenzeni ukonakala kweprotheyini kunye nokusetyenziswa kwamandla emisipha.
Ukuxilongwa
Njengoko u-myopathy kwi-hypothyroidism, ugqirha wakho uya kwenza uvavanyo olusemzimbeni kwaye akubuze imibuzo enxulumene neempawu zakho zemisipha. Angakhombisa nokuhlola iimvavanyo zegazi, ingakumbi i-panel function panel, kwaye uncoma i- electromyography .
Unyango
Unyango lwakho lwe-hyperthyroidism luya kuphilisa i-myopathy; Nangona kunjalo, kunokuthatha ixesha, ukuya kwiinyanga eziliqela, nokuba emva kokuba i-thyroid ibuyele kwiimeko eziqhelekileyo.
ILizwi
Umyalezo osuka ekhaya uya kuba izikhalazo ezixubileyo ziqhelekileyo kwisifo se-thyroid kwaye ngokubanzi ziyakuncitshiswa ngokusebenza komsebenzi wakho we-thyroid.
Sekunjalo, kubalulekile ukubona ugqirha wakho ukuba ubona ubuhlungu obutsha kunye / okanye obukhulu obuhlungu buhlungu okanye ubunzima. Ngelixa i-thyroid yakho ingaba yinto ephosakeleyo, kukho ezinye iimeko zempilo ezingabangela iimpawu zomzimba, kwaye le miqathango ifuna isicwangciso sonyango.
> Imithombo:
> Kim TJ et al. Umzekelo we-thyrotoxic myopathy ne-type 2 ye-fibre predominance. Exp Neurobiol . 2013 Sep; 22 (3): 232-34.
> Miller ML, i-DI DI. (2017). Hypothyroid myopathy. Aminoff MJ, uShefner JM, Ross DS, ii-eds. Isemgangathweno. Waltham, MA: UpToDate Inc.
> Sindoni A, Rodolico C, iPappalardo MA, iPoraro S, Benvenga S. I-myopathy ye-Hypothyroid: Inkcazo ekhethekileyo yeklinikhi yokuhluleka kwe-thyroid: Ukuhlaziywa kweencwadi. Ingxelo ye-Endocr Metab Disord . Ngo-2016 Dec; 17 (4): 499-519.
> UVillar J, uFolol HJ, uTorres SH, uRossch-Gonzalez A. I-Myopathy kwizigulane ezineesifo sikaHashimoto. Invest Clin . Ngo-2015 uMar; 56 (1): 33-46.