Kulula ukudibanisa i-lactase kunye ne-lactose.
Mhlawumbi uvile nge-lactose, yindlela yeswekile efumaneka kubisi kunye nezinye iimveliso ezisetyenziselwa ubisi. Abantu abaninzi banenkathazo yokugaya i-lactose - kungenxa yokuba abanalo i-lactase eyaneleyo, eyona enzyme imizimba yethu eyenza ukuba sincede sidle i-molecule ye-lactose.
Umzimba wakho awukwazi ukugaya kwaye ubambe i-lactose ngaphandle kokuba i-enzyme ye-lactase iyenze ukuyidiliza ibe ngamacandelo amabini eyaziwa njenge-glucose (ishukela elula) kunye ne-galactose (enye inhlobo yeswekile engumnandi kakhulu kune-glucose ne-fructose eyaziwayo. .
Ukuba awunayo i-lactase ngokwaneleyo emathunjini akho, le nkqubo ayisebenzi ukwenza i-lactose ibe yimilolekyuli encinane yeshukela. Yaye xa i-lactose ingaphuhliseki, ibangela iingxaki.
Ziziphi iintlobo zeengxaki? Ewe, i-lactose engapheliyo ingakhokelela ekukhungeni kwesisu, isithwathwa kunye nesifo sohudo.
Abantu abanexholongwane le-lactose bahlala befanele baphephe iimveliso zobisi (okanye ubuncinci bazinciphise) ukuze bagcine iimpawu zabo. Ngenye indlela, banokuthenga ubisi be-lactose kunye nezinye iimveliso zobisi zobisi.
Yintoni enxulumene ngayo nezifo zeCeliac?
Njengoko kuvela, i-enzyme lactase yenziwe ngamathumbu emathumbu, awona amancinci amancinci afana nomunwe wakho omathumbu.
Xa umntu enesifo se-celiac , ukusetyenziswa kwe- gluten kubangela ukuba i-immune system ihlasele i-villi ngokuphosakeleyo, ekhokelela ekuthiwa yi -atrophy ephangaleleyo , okanye ukukhulelwa kwe-villi.
Emva kokuba i-villi isifikile, umzimba unenkathazo yokuvelisa i-lactase eyaneleyo.
Ekubeni umzimba wakho udinga i-lactase ukugaya i-lactose, ukungabikho kwe-lactase kunokukhokelela ekuxhasweni kwe-lactose.
Ucwaningo luye lwabonisa ukuba abantu abafumene isifo se-celiac bangaphinda baxhomekeke kwi-lactose kwimveliso yobisi xa sele beqalile ukulandela ukutya kokutya kwe-gluten . Kungenzeka ukuba oku kwenzeka ngenxa yokuba amandla abo emathunjini ama-intestinal ukuvelisa i-lactase ibuyiselwe njengoko i-intestinal villi ikhula.
Kwisifundo esinye, umntu omnye kwa-15 waphinda wafumana amandla okugaya i-lactose (njengoko ilinganiswa novavanyo lokuphefumula kwe-hydrogen) zingangeenyanga ezintandathu zokungena-gluten. Abantu abayisithoba abasalayo abayi-14 kwisifundo bafumana amandla okugaya i-lactose kwisithuba seenyanga ezili-12 ukuqala ukutya.
Abaphandi bathi "inxalenye enkulu" yabantu abanezifo ezinqabileyo zibonakala zibuyela kwi-lactose-enyamezelayo (mhlawumbi ngenxa yokuba ngoku ivelisa i-enzyme lactase) emva komnyaka ekudleni okungenanto. Oogqirha kufuneka bavavanye ukunyamezela kwe-lactose ukuqinisekisa ukuba abantu abanezifo ezingenalo i-lactose-free, akuphelelanga ukuba i-lactose ikhululekile.
Kwakhona kunokwenzeka nokuba nolwazi olubizwa ngokuba yi-primary lactase. Oku kuthetha ukuba i-genes yakho ibeka ityala lokungabikho kwe-lactase (kunye nokungakwazi ukugaya i-lactose), kungekhona enye imeko yezokwelapha ezifana nesifo se-celiac.
(Ehleliwe nguJane Anderson)
Umthombo:
Ojetti V. et al. Ukunyanzeliswa kwe-lactose malabsorption kwizigulane ezingenasifo emva kokufumana ukutya okungahambisani ne-gluten. I-Scandinavian Journal yeGastroenterology. 2008; 43 (2): 174-7.