Yintoni eyenza i-Triple Negative Negative Other Breast Cancer?
Sibanzi
Ukufunyaniswa ukuba nomhlaza wesifuba kuyinto eyoyikisayo; ukufunyaniswa ukuba unomhlaza wesibeleko wesithathu (TB) unomdla owongezelelweyo. Njengamanje asetyenziswe unyango oluthile, oluthathwa iminyaka emi-5 ukuya kwe-10 emva kokuphela kwonyango olusebenzayo ukunciphisa umngcipheko wokuphindaphinda, alusebenzelanga njengonyango lwe-TNBC. Nangona abaphandi bazama ukufumana unyango olujoliswe kuzo oluya kunceda ukunciphisa umngcipheko wokuphindaphinda kwabo bafumene i-TNBC, enye ayikho ngeli xesha.
Oko Siyamaziyo Nge-TNBC
- Yonke imizuzu engama-30, umfazi wase-US ufumanisa ukuba unesithathu esichaphazelekayo
- Iba ngumdlavuza wesifuba
- Kunokwenzeka ukuba kubuyiselwe kwaye kunzima ukunyanga kuba akukho zonyango ezijoliswe kuzo
- Ukuba kuyenzeka, kunzima ukwenza njalo kwiminyaka emi-5 yokuqala emva kokunyanga okusebenzayo.
- I-Chemotherapy ibonise ukuba unyango oluyimpumelelo oluninzi lweengxube zebele zomhlaza.
Indlela i-INBC ihluke ngayo kwezinye i-Cancer Cancer
Umhlaza wesifuba asisinye isifo. Enyanisweni, isigama somhlaza sesifuba siquka iintlobo ezininzi kunye neentlobo zeengcingo ezenzeka kwibele; bafumanisa ukuba ngaba okanye abanayo i-receptors ezenza i-cancer yebele. Ezi zamukeli ziquka i- estrogen receptor, okanye i-ER; i-progesterone receptor , okanye i-PR kunye ne-epidermal growth factor receptor 2, okanye i- HER2
Xa aba bantu bekhona, banceda iqela lokunyanga lomhlaza lithatha isigqibo sokuba lungcono njani ukuphatha uhlobo oluthile lomhlaza.
Umhlaza wesibeleko se-ER, i-PR yomhlaza wesifuba esihle kunye nomhlaza webele we-HER2, unyango lubandakanya imishanguzo ekhusela, ephuculwayo okanye ekumiseni ukukhula komhlaza ngokujolisa abo bamkeli. La mayeza anikwa emva kokuphela kokonyango olusebenzayo, okuquka ukuhlinzwa, i-chemotherapy kunye / okanye unyango lwe-radiation.
Izidakamizwa ezifana ne- tamoxifen , kunye ne- aromatase inhibitors , zijolise kwi-estrogen receptor, izilwanyana ezijoliswe kwi-HER2 yi-Herceptin.
I-negative triple istytype ye-breasttype engenayo nayiphi na yezi zinto ezi-ezintathu ezifunyenweyo, ezisetyenziselwa iithagethi zonyango lomhlaza. Igama layo livela ekubeni kungenanto ye-ER, PR, kunye ne-HER2 receptors. Ngenxa yokuba i-negativeple triple ayinayo nayiphi na yale milambo, le ngqutyana yomhlaza wesifuba ayiphendulanga ku-tamoxifen no-Herceptin.
Phantse iipesenti ezingama-70 zesifo somhlaza we-breast is ER positive; Amaphesenti angama-15 eengxube zengxube zebele zi-HER2 ezilungileyo, kwaye iipesenti ezili-15 zeengcingo zebele zincinci ezintathu.
Unyango
I-TNBC idlalwa rhoqo kunye nokuhlanganiswa kokuhlinzwa okulandelwa yimisebe kunye / okanye i-chemotherapy. Izinketho zokuphanda ziyafana nezinye iisomhlaza zebele. I-Lumpectomy kunye neyeza zonyango zingabakho ukhetho ngokusekelwe kubukhulu kunye nendawo yesikhumba.
Imiba emininzi ingenza i-mastectomy ibe yindlela ekhethekileyo yokukhethwa kunye okanye ngaphandle kokuvuselelwa kwebele. Ukuba umfazi unesifo esikhulu, kunokufuna ukuba uphathwe ngekhemotherapy phambi kokuhlinzwa. I-Chemotherapy, esivame ukunikezelwa emva kokuhlinzwa, iyaqhubeka iyinkqubo enempumelelo kakhulu kwi-TNBC.
Uphando olutsha lwe-TNBC
Kuqhubeka uphando oluqhubekayo ukufumanisa unyango olutsha. Kwintetho kunye noDkt. Marc Hurlbert, iGosa eliPhezulu loPhando, kwiSiseko soPhando lweCanscer Breast wathi, "Iipotifoliyo zophando ze-BCRF zenza unyango olutsha zibandakanya uphando oluthile lwezonyango ezintsha ze-TNBC. Esinye sifundo sifaka ukuvavanya i-PARP inhibitors kwintsebenziswano kunye nezinye iziyobisi kwi-TNBC. "
Izinto zobungozi
I-negative triple ingavela kubasetyhini baluphi na ubudala, ubuhlanga kunye neentlanga. Kodwa-ke, kuyenzeka ukuba kwenzeke ngokuphindaphindiweyo kubomama base-Afrika nabase-Afrika nabama-American, kunye nalabo baseCaribbean kunye nabaseNicanese ababesetyhini abasemsebenzini, kunye nabafazi abane- BRCA.
Thintelo
Ngelinye igama, akukho, into emithathu engalunganga ayikwazi ukunqandwa. Ngeli xesha, akukho mhlaza wesisu onokuthintelwa. Kukho izinto ezinokuthi zinciphise umngcipheko wokufumana umhlaza wesifuba, njengokugcina ubunzima obusempilweni, ukuqhuba rhoqo, ukulandela ukutya okutsalwa kwezitshalo, ubukele ukutya okushukela, kugcina ukusetyenziswa kotywala kuncinci kwaye ugweme amafutha agcwele.
Nangona ukugcina impilo ephilileyo, into enokuzilungiselela yona yinto yokusebenza ngokukhawuleza, oko kungakhokelela ekufumaneni umdlavuza webele ngexesha lokuqala xa kulula ukunyanga.
Yazi imvelaphi yentsapho yakho yomhlaza webele, xubusha nodokotela wakho okanye ugqirha wezilwanyana kunye, ukuba kukho umhlaza wesibeleko kwintsapho, landela icebiso lonyango lakho ukuze uhlolwe.
Ukususela kumaphesenti angama-85 eengcinezelo zesifuba ezitholakala kwabasetyhini abangayazi imbali yesifo, kuyilungileyo ukuba baqale ukuhlolisisa kwiminyaka engama-40. Nangona utshintsho lwangoku malunga nexesha lokufumana i-mammogram yakho yokuqala kunye nokucwangcisa imimmogram rhoqo emva koko, yazi ukuba Izilwanyana kunye neemviwo zokuzibamba ubomi zidlala indima ebalulekileyo ekutholeni kwangaphambili.
I-Word Fron
Ukuba ufumene ukuba unomdlavuza wesibeleko wesithathu, ungadinga unyango oluvela kumagqirha anesifo somhlaza wesibeleko kunye nokuphatha rhoqo abafazi abaye bafumanisa ukuba banomhlaza wesibeleko wesithathu. Amabele akho adinga ukuvavanya ngokucokisekileyo kwaye kufuneka ukwazi zonke iinketho zakho unyango ngaphambi kokuqala unyango. Ukuba uneminyaka engaphantsi kweminyaka engama-60 ubudala, i-oncologist yakho yonyango iya kufuna ukuba ube nokuhlolwa kofuzo ukuze uqinisekise ukuba ungumphathi we-BRCA, njengokuba ezinye iindlela zonyango zinokusebenza kakuhle.
Kubalulekile ukuba umntu ahambe nawe ukuze adibane kunye nodokotela wakho ogqirha kunye ne-oncologist yakho kunye nawuphi na umnikezeli wonyango. Ukusebenza njengeendlebe zombini, le mntu kufuneka ibhale inkcazo epheleleyo yento ugqirha ekuchazela ngayo ngento emithathu engalunganga; zakho iindlela zokonyango kwaye kutheni ezi zikhetho zakho. Ekuqaleni, ingxaki emithathu ingaba nzima ukuyiqonda, ingakumbi inika uxinzelelo lwakho. Uya kuvuya ukufumana amanqaku ekuhlaziywa emva kwentlanganiso nganye.
Unganqikazi ukubuza imibuzo emininzi yeqela lakho lonyango njengoko lithatha ukuba uqonde isicwangciso sakho soonyango. Fumana uluvo lwesibini kwelinye ugqirha onamava amaninzi ekuphatheni izigulane ezineengxaki ezintathu zomhlaza wesifuba.
Fumana kwimibutho enolwazi, iinkqubo, kunye nenkxaso yeenkonzo ezijongene nezinto ezintathu ezimbi, ezinjenge:
- Ukuphila ngaphaya kweCarcer Breast
- Isiseko seCanscer Breast Negative
- CancerCare
> Imithombo:
> I-American Cancer Society. Ingxaki yomhlaza wesibeletho isenza njani?
> IBREASTCANCERORG I-Cancer Breast Negative Breast Cancer.
> Isiseko seSifo seNtsholongwane kaZwelonke. Yintoni iCatter Negative Breast Cancer?