Yintoni esiyayazi malunga nePropecia kunye nomhlaza wesibeletho ? Ngaba uphando lubonakala lubonisa inzuzo ekhuselekileyo yamadoda athabatha iProteka ayitshintshe ngokwenene ukuba oogqirha bancomela njani amadoda enengozi enkulu yokuvelisa umdlavuza wesibeletho?
Uphando ngePropecia kunye neCarstate Cancer
Ubu bungqina bufikile phambili ukuba iPropia (i-finasteride)-isilwanyana esisetyenziselwa ukuphatha umthambo wesimo somntu-sinokukunceda ekukhuseleni umdlavuza wesibeletho kumadoda anomngcipheko omkhulu wokuphuhlisa eso sifo.
Olunye uphando luye lwabonisa ukuba iProtepia (okanye iziyobisi ezifanayo) inokulibazisa ukuqala komhlaza wesibeletho kumadoda athile.
Kwakudala becinga ukuba iPropecia okanye iziyobisi ezifanayo zinokunikela ngezibonelelo ezikhuselekileyo zinikezwa njani ukuba zisebenza njani emzimbeni. Ipropecia enye yeklasi yezilwanyana ezichasene nemiphumo ye testosterone emzimbeni. I-Testosterone yaziwa ngokuba yenye yezona zihamba phambili zokukhula komdlavuza wesibeletho.
Oko kubalulekile ukukhumbula ngezi zifundo kukuba baqala kuphela. Ukongezelela, amanye amadoda athe athatha iProtepia okanye iziyobisi ezifanayo kwizame zokuthintela okanye ukulibazisa umdlavuza we-prostate nazo zihlangabezane nemiphumo ebalulekileyo.
Ziziphi ezinye zezona ziphumo ezibaluleke kakhulu zeempembelelo zeProtepia?
Ngenxa yokuba iProtepia iyayichaphazela imiphumo ye testosterone emzimbeni, iziphumo ezingundoqo zesondo zingakhula. Kwisifundo esinye, malunga ne-1/3 yamadoda ayeke ukusetyenziswa kwePropecia ngezizathu ezingekho komhlaza.
Ukongezelela, izifundo zibonise ukuba izinga le- PSA lamadoda eProtepia lingabhalwa njengento ephantsi, ngokubangela ukuba i-cancer ilahleke.
Ipropecia kunye neProstate Cancer Incidence
Okubaluleke ngakumbi, ezinye izifundo zibonise ukuba nangona amadoda athatha iProtepia anokufumana ithuba elincinci lokuvelisa umdlavuza weprotate, loo mdlavuza ophuhliswayo udlala ukuba ube ngowona mgangatho ophezulu kwaye unobundlobongela.
Propecia kunye neProstate Cancer Survival
Nangona iziganeko zesifo somhlaza wesifo seprotate sinciphisa malunga namadoda asebenzisa i-Propecia, uphando alukabonakali ukuba amayeza anayo nayiphi na impembelelo ekusindeni, mhlawumbi kumdlavuza wesibeletho okanye kwizinto ezibangela ukufa. Isizathu esingaba kukuba kwizifundo kuze kube yiminyaka kukho ukufa okumbalwa kakhulu, okwenza kube nzima ukubalavanya le nani-manani, okanye mhlawumbi ngelixa linciphisa isiganeko akungenzi umehluko ekusindeni. Enye inokuthi i-Propecia iyancipha iziganeko zeekliniki eziphantsi, kodwa ayinayo impembelelo kwizinga eliphezulu (ngaphezulu kunokwenzeka ukuba libulale).
Ngaba oogqirha bancoma kakhulu iPropecia ye-Prostate Cancer Prevention?
Namhlanje, bambalwa oogqirha bancoma iProtepia kuninzi lwabantu abanomdlavuza wesibeletho. Oku kubaluleke kakhulu ngenxa yezinye iziphumo ezichaphazelekayo ezinokuthi ziphumo, kodwa kungenxa yokuba kungenzeka ukuba amadoda athatha iProtepia okanye izidakamizwa ezifanayo ziza kuhlakulela ukwanda komdlavuza (njengoko ezinye iziphumo ziphakanyisiwe).
Ngokubanzi, ukuba iPropecia isilwanyana onomdla ekuthatheni ithemba lokuthintela umdlavuza weprotate, xela ugqirha uze uqiniseke ukuba uhlaziye zonke iinkqubo kunye neengxaki zesigqibo.
Imithombo:
UAzzouni, F., noJ. Mohler. Indima ye-5a-reductase inhibitors ekukhuselweni komhlaza kunye nesonyango. Urology . 79 (6): 1197-20.
Hoque, A. et al. Umphumo we-finasteride kwi-serum androstenedione kunye nomngcipheko wesifo somhlaza wesifo seprotate ngaphakathi kwilingo lokuthintela umdlavuza we-prostate: umphumo wecala kwi-high-and-grade-grade grade. Urology . 2015. 85 (3): 616-20.
Murtola, T. et al. Ukuvuvukala kumzimba wesifo seprotate kunye nesifo somhlaza wesifo seprotate kwisandla se-finasteride se-Prostate Cancer Prevention Trial. I-Epidemiology ye-Cancer Biomarkers kunye nokukhusela .
National Cancer Institute. Ukukhusela i-Prostate Cancer - kwiingcali zempilo (PDQ).
Thompson, I. et al. Impembelelo ye-finasteride ekuphuhliseni umdlavuza wesibeletho. I-New England Journal of Medicine . 2003. 349 (3): 215-34.