Ifomu yokuvuselela ubuchopho inesithembiso sokuphatha iinkalo ze-autism
Umphandi uthi "Ufumene i-Pathology of Autism"
UDkt. Manuel Casanova ubamba isihlalo esinikezelwe kwiYunivesithi yaseKentucky. Ubhaliwe amaphepha amanqaku ahlaziywe ngontanga, kwaye ufumana inkxaso evela kwiiNational Institutes of Health. UDkt. Casanova uqhuba uphando malunga neengqondo ze-autistic - kwaye, ngokutsho kwakhe: "Ndicinga ukuba sifumene ukukhubazeka kwe-autism.
... ichaza kakhulu, konke kuyaqondakala. "
UDkt. Casanova akakholelwa nje ukuba ufumene i-patism ye-autism, kodwa usebenza kwonyango enokukwazi ukunciphisa iimpawu ze-autistic of hypersensity without compromising the creativity and ability skills that make people autistic.
IiMicolumns kwi-Autistic Brain: Iindaba ezilungileyo kunye neendaba ezimbi
Ingxenye yangaphandle yengqondo ibizwa ngokuba yi-neocortex. Kwi-neocortex ngamaqela eeseli ezibizwa ngokuba yi-minicolumns. Ezi zincinci zincinci encinci yeeseli ezinokukwazi ukulungisa ulwazi. Ngokuqhelekileyo, iifolumns ziquka iiseli ezininzi, ezibizwa ngokuthi i-neurons, ezivumela ukuba unxibelelwano kungekuphela kwimizuzu yamagama kuphela kodwa nakwiindawo ezahlukeneyo zobuchopho.
IiMicolumns kubantu abano-autism bancinci kwaye baninzi kunezinto eziqhelekileyo. Ukongeza, i-neurons nganye kwi-minicolumn nganye iyancishiswa ngobukhulu.
Oku kungabikho kokulungileyo nokubi, uthi uCasanova: "Ukusukela kobuchule bokuxhamla phakathi kwe-neurons ngumsebenzi wesayizi yeeseli, ubukho bee-neurons ezincinci kwiibilini zezigulane ze-autistic zinomphumo omkhulu kwiindlela ezahlukeneyo zobuchopho Imisebenzi yobuninzi efuna iimpawu ezininzi (umz., ulwimi) lunokukhubazeka ngelixa ezo zixhomekeke kwiinkcukacha ezimfutshane (umz., ukusetyenziswa kweemathematika) zingagcinwa okanye ziqinisekiswe. "
Ngamanye amazwi, abantu abane-autism bahle kakhulu kwiinto ezinokuthi ziqhutywe kwingingqi enye yengqondo - njenge-math and visual discrimination. Kodwa-ke, zimbi nakakhulu nantoni na efuna ukulungelelaniswa phakathi kweendawo ezahlukeneyo zobuchopho - njengezakhono zentlalo , ulwimi kunye nokuchaswa kwabantu.
Ukufakela okubi phakathi kweMinicolumns Kungabangela Iingxaki ezixhasayo
Ngokutsho kweCasanova, esinye isiphumo esisecaleni se-minicolum esongeziweyo kunye neeseli ezincinci "i-stimuli ayisekho kwii-minicolum ekhethekileyo kodwa kunokuba ikhuphe kwiindawo ezincinci ezifutshane kunye nokubonelela nge-amplifier effect. Oku kungachaza ukuxhomekeka kwezilwanyana ezithile ze-autistic kunye ukutshatyalaliswa. "
I-Casanova ifanisa le manzi equlethwe kwisitya. "Iifayili ezingavimbelayo zisebenza ngendlela efanelana nekhefu lokuhlamba. Xa usebenza kakuhle kwaye uguqula ngokupheleleyo ibhegi ibhedu lokugeza livimbela amanzi ukuba ahlasele phantsi." Abantu abane-autism baneepaleni zokuhlamba.
Ukwandiswa kokuQiniswa kweziNdaba ezinokuFunda kunye noKhuseleko ngaphandle kokunciphisa ukudala
UDkt. Casanova ukholelwa ukuba kunokwenzeka ukwandisa "ukugxininisa" okujikeleza i-minicolumns, ngaloo ndlela unciphisa ukugqithisa okubonakalayo kunye nokuxhamla.
Ubuhle bemfundiso yakhe kukuba, ezi ziphumo ezingalunganga zingabhekiswa ngaphandle kokuchaphazela amandla abantu abane-autism ukucinga, ukuqonda nokudala ngaphandle kwebhokisi.
Nantsi indlela esebenza ngayo: Ngokutsho kweCasanova, "impahla ephambili yale [i-minicolumn] iiseli kunye nezicwangciso kukuba zimi kuma-90 degrees ukuya phezulu kwe-cortex. I-Casanova ichaza ukuba i-transcranial stimulation magnetic stimulation (TMS) inokuthi "ifake i-magnetic field kwi-cortex," ngokuqinisekileyo ukuqinisa ukugxininisa kwimizuzu yamaminithi. Olu unyango luya kuba (ngokubhekiselele kuphando olukhoyo) lunomphumo omncinci wecala.
Okubaluleke kakhulu, ayiyi kuba nefuthe eliphambili lokutshintsha ubuntu okanye iinkqubo zengcinga zomntu ophathwayo.
Ingaba i-TMS ingaba yi "Deal Real Deal?"
Le ngcamango ayinangqungquthela njengoko ingava. Enyanisweni, i-TMS sele ibonakalise iluncedo ekuphatheni izifo zengqondo ezinjenge-schizophrenia kunye nokudandatheka. Uvavanyo lwezonyango luqhubekela phambili ngokusebenzisa i-NIH ukuvavanya ukusetyenziswa kwe-TMS ekuphatheni amazwi e-hallucinatory. Kwixesha leminyaka emininzi, imibutho eyahlukeneyo iye yazama iimvavanyo ze-TMS - kodwa ngoku akukho mvumelwano malunga neziphumo. Nangona iilingo zaseHarvard nakwezinye iindawo zibonakala ziphethe isithembiso, kwaye amanqaku kumaphephancwadi afana ne-Newsweek ayakhawuleza, i-TMS ihlala yindlela yokwelapha engenakulungele ukusetyenziswa ngokubanzi.
Iingxelo:
Udliwanwano lwefoni kunye noDkt. Manuel Casanova. Septemba, 2006.
I-Casanova MF, i-Kooten IAJ van, i-Switala AE, i-Engeland H van, i-Heinsen H, i-Steinbusch i-HWM, i-Hof PR, i-Schmitz C. Iimeko ezingekho phantsi kwe-cortical iziganeko ezincinci kwi-loberal lobes yezigulane ze-autistic. Uphando lweeNzululwazi ngo-2006; 6 (3-4), 127-133.
I-Casanova MF, i-Kooten IAJ van, i-Switala AE, i-Engeland H van, u-Heinsen H, i-Steinbusch i-HWM, i-Hof PR, i-Trippe J, i-Stone J, i-Schmitz C. I-Minicolumnar inormality in autism. Acta Neuropathologica 2006; 112 (3), 287-303.
I-Casanova MF, Ukungahambi kakuhle kweeCortical Circuitry KwiBrains Of Autistic Individuals. Ukunikezwa kwiNgqungquthela yamazwe onke e-All Wales, i-AWARES, ngo-2006.
Chae, JH, Nahas, Z., Wassermann, E., Li, X., Sethuraman, G., Gilbert, D., et al. (2004). Ucwaningo lokuphepha lokuqhubela phambili lokuvuselela i-transmranial magnetic stimulation (rTMS) kwi-Tourette's syndrome. I-Neurology, i-17 (2), 109-117.
Mantovani, A., Lisanby, SH, Pieraccini, F., Ulivelli, M., Castrogiovanni, P., & Rossi, S. (2006). Ukuphindaphinda ukuvuselela i-magnetic stimulation (rTMS) kunyango lwe-dispersive disorder (OCD) kunye ne-Tourette's syndrome (TS). I-International Journal ye-Neuropsychopharmacology, 9 (1), 95-100.