Ukubaluleka kwe-MPV njengengxenye yeComputer Blood Count (CBC)
Usenokuba ubonile iileta "MPV" njengenxalenye yovavanyo lwakho olupheleleyo lwe-Blood Count (CBC) , uvavanyo olusetyenziswe kwimvavanyo yokuhlolwa kwezempilo, kunye nokujonga unyango kwiimeko ezininzi zempilo. Uvavanyo lwe-CBC luvavanya iiseli zakho ezibomvu zegazi (iiseli ezithwala oksijeni), iiseli zegazi ezimhlophe (iiseli zokulwa nosuleleko), kunye neeplatelet (iiseli ezenziwe ngama-clot). I-MPV (emele umthamo weplatelet) isilinganiselo sobukhulu bomlinganiselo wamaplatelet (thrombocyte), icandelo legazi lakho eliza kukuncedisa igazi lakho.
Kwi-CBC yakho uza kuba neengxelo ze-platelet count count kunye ne "indices platelet" ezifana ne-MPV. Uya kuphawula ukuba kukho iikholeji zobalo bakho obomvu begazi kunye nombolo yegazi elimhlophe. Ezi nkcazo zinika inkcazelo echanekileyo yeengxaki ngeeseli zakho zegazi. Enyanisweni, ngamanye amaxesha umntu unokufumana amanqanaba aqhelekileyo eeseli zegazi, kodwa ukufunda okungavumelekanga kumanqaku kungabonisa ugqirha wakho ingxaki. I-MPV inceda kakhulu ekunqumeni imbangela ye-thrombocytopenia, isibalo esiphantsi seplatelet, kodwa sinokuvavanya luncedo nangona inani lakho leplatelet liqhelekile.
Kutheni ubungakanani obukhulu beeplatelet zibalulekileyo, kwaye kuthini ukuba i-MPV yakho iphakamileyo okanye iphantsi kwebala eliqhelekileyo? Makhe sithethe ngezizathu ezinokwenzeka zePMV ephezulu okanye ephantsi, kunye nendlela iP MPV ingasetyenziswa ngayo ukuxela umngcipheko kubantu abanezimo ezithile zonyango.
I-Platelet Volume (MPV) kunye neMpilo Yakho
Iiplatelet ziseli zithwala uxanduva lokwakha iimbophu.
Ziyimfuneko ekusigcineni ekuphumeni kwegazi xa sinqunywe kwaye silawulwa ukuphuma kwimizimba yethu. Xa kuqhutyelwa ihlunu kwesikhumba okanye ngaphakathi kwimizimba yethu, iiplatelet zihlanganiswe ukucoca umgodi. Ezinye iinkalo zokuqhawula (ezinjengezo ezingekho kwi-hemophilia) zibizwa ngoko mhlaba ukukhusela ukuphuma kwamanzi.
Iiplatelet ziveliswa ngethambo lomongo ngamaseli abizwa ngokuthi megakaryocytes. Iiplatelet ngokwayo ziyiqhekeza ze-megakaryocytes, ngaphandle kwenuclei, ezikhutshelwe kwigazi ukusuka kumnkantso. Ngokuqhelekileyo, iiplatelets ezincinci zinkulu kuneeplatelets ezidala.
Amanqanaba aqhelekileyo wePlatelets kunye neMPV
Xa ukhangela i-MPV, kubalulekile ukujonga kwinqanaba leeplatelet kunye ne-MPV.
Uhlobo oluqhelekileyo lweeplatelet (oku kuyahlukahluka phakathi kweelabhu) ngu-150,000 ukuya kuma-450,000 nge-milliliter. Ngokuqhelekileyo, abantu banokunyamezela amanqanaba eeplatelet ukuya kuma-50,000 ngokunyunyuzwa okufutshane. Inqanaba leplatelet elingaphantsi kwama-20,000, nangona kunjalo, lunokubangela ukongela ubomi. Izihlomelo zePlatelet ziquka:
- MPV (kuxoxwe apha).
- PDW (ububanzi bokusabalalisa kweplatelet). I-PDW ichaza ukuhluka kobukhulu beeplatelets.
Ekunqumeni isizathu esinokwenzeka sePMV engafanelekanga, kubalulekile ukujonga ukuba ngaba inani leplatelet liqhelekile, liphezulu okanye liphantsi.
Ukulinganiselwa kuVavanyo / Ukuchaneka kwe-MPV
Isinyathelo sokuqala xa ugqirha ebona ukuba une-MPV engavumelekanga iya kuba ukuvavanya ukuchaneka kovavanyo. Ukuba kubonakala ngathi kukho iphutha kunye ne-drawn draw yegazi, uvavanyo luya kuphinda luphindwe.
Uvavanyo lweCBC lufuna igazi elingenayo igazi (igalelo legazi elibanjwe kwi-tube equlethe i-anticoagulant ukuze igazi lingagqithanga) kwaye ngokuqhelekileyo lithathwa kwi-tube top purple.
Ukuba igazi lithathwa kwi-tube ngaphandle kwe-anticoagulant, liya kuguqulwa, kunikezele umphumo ongaqhelekanga kokubalwa kweplatelet kunye ne-MPV. Ukuba ugqirha wakho ukholelwa ukuba ukuqhuma kwenzeka, enye isampuli iya kubanjwa. Abanye abantu badinga igazi labo elithatyathwa kwiphubhu eyahlukileyo ngokupheleleyo, njengoko iiplatelets zabo zisenokuthi ziqhube kunye ne-anticoagulant esetyenziswe kwi-tube top.
Xa ixabiso le-MPV liphakamileyo, i-lab iya kudla ngokuyijonga nge-differentiate blood smear, uvavanyo olujonga iinombolo zeentlobo ezahlukeneyo zeeseli zegazi ezimhlophe ezikhoyo. I-teknoloji iya kwenza kwaye ichithe isilayidi segazi lakho kwaye lijonge phantsi kwe-microscope ukubona ukuba iiplatelet zidibanisa kunye okanye ukuba unenaplatelets ezinkulu.
Oko kuthethwa, abanye abantu banenaplatelet ezinkulu okanye ezinkulu ngenxa yezizathu ezingezantsi.
Izizathu zePlatelet Volume High (MPV)
I-MPV ephezulu ibonisa ukuba kukho iiplatelet ezincinci ezijikelezayo kwigazi lakho. Ukuba unenkqubo efana nokuhlinzwa okukhulu, umzimba wakho usebenzisa amaplatelets ukulungisa izicucu kwimithambo yegazi. Ekuphenduleni, umongo wakho wethambo ukhulula ezinye iindawo ezincinci, iiplatelets ezinkulu, kunye nokuphakama kwe-MPV yakho.
Ukuphonononga i-MPV ephezulu kunceda kakhulu ekunqumeni imbangela yesibalo esiphantsi seplatelet, kwaye isizathu esona siqhelo "kukutshatyalaliswa," okanye iiplatelet zonakaliswa ngandlela-thile, njengezikhuhlane ezinokuvelisa (bona i-ITP ngezantsi).
I-MPV ephezulu kunye nenani leplatelet eliphezulu , ngokuchaseneyo, lidla ngokuba ngenxa ye-thrombocytosis ephambili okanye ebalulekileyo (imeko apho umzimba uvelisa iiplatelet ezininzi, ngokuqhelekileyo ngenxa yokuguquka kwemfuyo), okanye umhlaza.
I-MPV ephezulu nebala eliqhelekileyo leplatelet libonisa izimo ezifana ne-hyperthyroidism, okanye i-leukemia engapheliyo.
Imiqathango enokubangela ukuba iPVV ephakamileyo iquka:
- Idiopathic thrombocytopenic purpura (ITP): i-ITP yimeko apho i-immune system ibhubhisa iiplatelet. Iimeko ze- idiopathic thrombocytopenic purpura inegama elide, kodwa ukujonga nganye yemigaqo kwi-ITP kwenza kube lula ukuyiqonda. Idiopathic ligama elisetyenziswe ukuchaza imeko engaziwayo. Ingongoma yezobugqirha ngokuba "asinayo inkcazelo" kutheni kwenzeka. Igama leengcambu elithi "thrombo" libhekisela kwi-clot (umsebenzi weeplatelet) kunye ne "penia" ibhekisela ekusileni, ngoko i-thrombocytopenia ibhekisela ekusileni kweeplatelet. I-Purpura yigama lonyango lokutyhafaza, ngokuqhelekileyo ukutyumza okukhulu. (Igama elithi petechiae libhekisela kumanqaku amancinci amancinci elukhumbeni (imincinci emincinci) engagcini xa ucinezela.)
- Iidlingozi zegazi ezifana ne-leukemia.
- Isifo sesibindi esingeyotywala.
- Ukungaqhelekanga kwe-Genetic kwiiplatelets.
- I-Bernard-Soulier Disease (isifo seplatelet syndrome).
- Umongo we-Bone ovuselela iziyobisi, njenge-erythropoietin okanye i-thrombopoietin.
- Iswekile yemellitus.
- Izifo zokuphefumula.
- Sepsis.
- Hyperthyroidism.
- Ukuhlaselwa kwentliziyo (jonga ngezantsi).
- I-pre-eclampsia (i-toxemia yokukhulelwa) ne-HELLP syndrome.
- Iintsimbi zentliziyo.
Iingxaki zePlatelet Volume Low (MPV)
Izizathu ezinokwenzeka zePMV ephantsi ziyakwazi ukuhluka ngokuxhomekeka kwimibala yeplatelet. I-MPV ephantsi kunye nenani leplatelet elingaphantsi lingabhekisela kwiingxaki ezichaphazela umongo weethambo oyehlisa okanye wehla ukuveliswa kweeplatelet, ezifana nesimo esibizwa ngokuba yi- aplastic anemia . I-MPV ephantsi nebala eliphezulu leplatelet lidla ngokubhekiselele kwintsholongwane, ukuvuvukala okanye umdlavuza. I-MPV ephantsi nebala eliqhelekileyo leplatelet liqhelekile ukuhluleka kwezintso ezingapheliyo.
Izizathu ezinokwenzeka zePVV ephantsi ziquka:
- Ukungaphumeleli komnxeba we-bone (iiplatelets ezidala zincinci, ngoko i-MPV iphantsi xa umongo wethambo ungabonakali kakhulu).
- I-Splenomegaly (ukwandiswa kwetyeni). Nge-hypersplenism, iiplatelets "zihlala zilandelwa" kwipeni.
- Ukungaphumeleli kwengqondo
- Amachiza anqanda ukubunjwa kweplatelet (njengezonyango zamachiza).
- Hypothyroidism.
- Ukunqongophala kwe-Iron anemia.
- HIV / AIDS.
Ukuxilongwa
Ukuxilongwa kwe-MPV ephakamileyo okanye ephantsi kuya kuxhomekeka kwizinto ezininzi ezibandakanya isibalo seplatelet, isibalo seesibomvu segazi kunye nombolo yamhlophe yegazi. Uvavanyo lomongo lwethambo lungadingeka ukuba kukho inkxalabo malunga nomnatha wethambo ongasebenzi okanye umhlaza ungabakho. Oko kwathiwa, ukuvavanywa kunokuba kulula njengoko kuhlola iimvavanyo zomsebenzi we-thyroid.
I-MPV ephezulu, i-Heart Heart, neStroke
Kwiminyaka yakutshanje sele kufunyenwe i-MPV inokukunceda ekuhloleni kwangaphambili ukuhlaselwa kwentliziyo. Uphando luncinci, kodwa ucinga ukuba iPMV ephezulu iyakwazi ukuxela ingozi yokuba umntu onesifo senhliziyo uya kuba nesifo senhliziyo, kwaye uqikelele ukuba umntu ohluphekileyo uhlaselwa ngabantu abanobuchopho be-myocardial. Ngokufanayo, i-MPV ephakamileyo inokuba yinto esengaphambili yokubetha, kunye nokubonelela ingcaciso kulabo abanokuyenza kakubi emva kwesifo. Izifundo zikhangelekile ukuba zibone ukuba i-MPV ephakamileyo ingaba naluphi na indima ekuqikeleleni umngcipheko wee-clots zegazi (inzulu ye-vein thrombosis kunye ne-pulmonary emboli), kunye nesifo se-peripheral disease.
I-MPV NjengeMakishi yokuHlaziya
Ukongezelela kwendima enokubaluleka kwiziphumo zesifo senhliziyo kunye nesifo sokushaya, iziphumo ziye zafumanisa ukuba i-MPV inokuthatha inxaxheba ebalulekileyo kwimimiselo enjengobunzima be-sepsis kwiintsana ezisandul 'ukuzalwa, isalathiso kunye nomhlaza wesifuba, ukucacisa umdlavuza we-ovarian kwiintsholongwane ze-ovarian tumors , nangona ekufumaneni i-appendicitis.
Ngezantsi kwiPlatelet yoMqulu
Umthamo weplatelet ophakathi (MPV) ngumlinganiselo wobukhulu beeplatelets kwaye unokudlala indima ebalulekileyo ekufumaneni izifo nokuba ngaba inani leplatelet liphezulu, liphantsi okanye liqhelekile. Ukongeza kwimeko yokuhlola uvavanyo, siyafunda ukuba i-MPV inakho ukukwazi ukudlala indima ebangelwayo kwiimeko ezinjengeesifo senhliziyo, kwaye ukuba kunjalo, inokubakhokela oogqirha ukuba ngabaphi abantu kufuneka balandelwe ngakumbi okanye bafumane unyango.
> Imithombo:
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> Kasper, uDennis L .., u-Anthony S. Fauci, noStephen L .. Hauser. Iinqununu zeHarrison zeMithi yoPhakathi. ENew York: imfundo kaMc Graw Hill, 2015. Print.
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> Noris, P., Melazzini, F., kunye no-C. Balduini. Imisebenzi emitsha yePlatelet yokuQinisekisa iVolith Volume in Practice Clinic Practice? . Platelets . 2016. 27 (7): 607-612.