I-Plasmapheresis ngamanye amaxesha isetyenziswa njengonyango kwizifo ezininzi ze-neurological kuquka i-MS, ngokukodwa ngexesha lokuphindaphinda kanzima elingaphenduliyo kwi- corticosteroids . Inkqubo engenabuhlungu, kunye nemiphumo engathandekiyo ayifumaneki.
Yintoni iPlasmapheresis?
I-Plasmapheresis, eyaziwa ngokuba yi- plasma exchange exchange , yinkqubo apho umatshini ngaphandle komzimba womntu ususa igazi kumntu aze ahlule icandelo le-plasma yegazi-i-plasma ibe yinxalenye yamanzi okanye igalelo legazi.
Emva koko i-plasma ilahliwe kwaye ithathelwe indawo yohlu hlobo oluhlukileyo, oluqhelekileyo lunikela nge-plasma okanye isisombululo se-albin, ngaphambi kokuba kubuyiselwe kumntu.
Iyini Injongo yePlasmapheresis?
Injongo ye-plasmapheresis kukususa ingozi okanye "into embi" egazini. Kwimeko ye-MS, ezi zixhobo zemizimba yomzimba ehlaselwa kwinkqubo ye-nervous central.
Inkqubo
Ngexesha le-plasmapheresis, iinaliti ziza kufakwa zombini kwiingalo zakho, okanye ngamanye amaxesha zibe kwenye indawo, njengentamo, ukuba imifuno engalo ayikwazi ukufikelela. Igazi liya kuthi likhishwe emzimbeni wakho ngokusebenzisa inaliti ingalo enye. I- anticoagulant (ngokuqhelekileyo i-citrate) yongezwa kwigazi ukuyikhusela ekubeni iguqulwe. Igazi lakho liya kwandula lihambe kwibhubhu ibe "kwi-cell separator". I-cell separatorator yi-centrifuge ehlukanisa i-plasma ukusuka kwezinye iindawo zegazi lakho, eziyizixhobo zamaseli (ezibandakanya iiseli ezibomvu zegazi, iiseli zegazi ezimhlophe kunye neeplatelet).
Izixhobo zamaselula zidibene kunye nomxhasi we-plasma obanikezelayo kwaye babuyele kuwe ngedaliti kwenye ingalo. Kwezinye iimeko, oku kwenziwa ngedaliti enye kwaye ukwahlukana nokuhlaziywa kwenziwa kwiibhentshana ezincinci.
Yintoni evakalelwa ngayo?
Zonke iimanyathelo ezikhankanywe ngasentla zenzeke ngokuzenzekelayo nangokuqhubekayo.
Amava esigulane afana nokuba neenaliti ezimbini / i-catheters eziphakathi kwe-IV kunye nokubukela igazi kuphuma kwelinye icala, ngomatshini, kwaye ubuyele ngaphesheya. Inqubo yonke ithatha ii-2 ukuya kwi-4 iiyure zokugqiba.
Abantu banokuziva benento encinci okanye i-head-headed from the procedure. Kwakhona, abanye abantu babika ukuba i-anticoagulant yongezwa kwigazi okanye ezinye izixhobo zamanzi ezichithwayo zisetyenziselwa ukubetha okanye izikhonkwane kunye neenaliti ukuvalelwa eminwe nasezinzwaneni. Kukho umonakalo omuncu emlonyeni. Kungase kube nentshutshiso encinane kunye nokukhathala.
Mngcipheko
Imiphumo emibi kakhulu evela kwi-plasmapheresis ayinqabile. Into ephawulekayo yile i-anaphylaxis, eyona nto ibangela ukunyuka kwamanzi kwi-plasma. Esi sizathu sezizathu zokuba kutshintsho lwe-plasma lwenziwa kwimeko yokubeka iliso.
Izifo ezivela kwi-plasmapheresis aziqabile, ngokukodwa zisebenzisa i-teknoloji entsha kunye ne-stereal substitution fluid. Nangona kunjalo, abantu banokuthi bathambekele ekubambeni into emva kwe-plasmapheresis, amaninzi amaninzi omzimba asuswa, kwaye loo mntu unokuba ngumzimba onokuzenzekelayo.
Ezinye iziphumo ezichaphazelekayo ziquka:
- Ubunzima bokuziphendulela, ezivakalelwa njengezilwanyana, umkhuhlane okanye ukugqithisa okufutshane
- Ukuphuma kwegazi
- Ihlwili legazi
- Isiqhelo senhliziyo esingaqhelekanga
- Ukuhla kwegazi
- Ukuqhawukelwa ngumphefumlo
- Ukugquma okanye ukuvuvukala
Okukwintsusa
I-Plasmapheresis ngokuqhelekileyo yinkqubo ekhuselekileyo neyanyamezelwayo eyenziweyo. Oko kuthethwa, ayisetyenziswanga rhoqo kwi-MS - kuphela xa i-MS ephindaphindiweyo yokuphindaphinda i-MS inzima kwaye ayiphenduli kwi-regimen yonyango ye-steroid. I-Plasmapheresis ayisetyenziswanga ukuphatha i-MS ephambili okanye yesibini eqhubekayo.
Imithombo
Cortese I et al. Uhlaziyo olusekelwe kwiingcebiso: I-Plasmapheresis kwiintsholongwane ze-neurologic: Ingxelo yeTherapeutics kunye neCommittee Committee Assessment ye-American Academy ye-Neurology. Neurology . 2011 Jan 18; 76 (3): 294-300.
Fridey JL, Kaplan AA. "Umbhalo kunye neendlela zokuguqula i-plasma." Isemgangathweno. Ukuhlaziywa ngo-Matshi 31, 2010.