I-Methimazole / i-Tapazole yezifo zeMangcwaba

I-Antithyroid Izidakamizwa ezisetyenziselwa ukuphatha izifo zamangcwaba kunye ne-Hyperthyroidism

Izidakamizwa ze-Antithyroid - nazo zibizwa ngokuba yi-thioamides - ziyeza unyango lwe-thyroid (i-hyperthyroidism) ngokuthintela i-thyroid gland ikhono lokuvelisa i-hormone ye-thyroid. Xa unyango lwe-thyroid engapheliyo, edlalwa ngokugqithiseleyo kwiimeko ezizimeleyo ezibizwa ngokuba yi-Graves's disease, kubaluleke kakhulu ukunciphisa ukuveliswa kwe-hormones ye-thyroid, ikakhulukazi i-hormones thyroxine (T4) kunye ne-triiodothyronine (T3).

Izidakamizwa ze-Antithyroid zisebenza ngokwenza kube nzima ukuba umzimba usebenzise iodine, ngaloo ndlela uvimbele ukubunjwa kwamahomoni e-thyroid kwi-gland.

I-antithyroid yonyango lonyango linye yonyango lwe-hyperthyroidism kunye nesifo se-Graves. Ezinye iindlela zonyango ziquka i-iodine ye-radioactive (RAI) kunye nokukhutshwa kokukhutshwa kwazo zonke okanye inxalenye ye- thyroid gland .

Kukho izibini ezimbini eziphambili ze-antithyroid ezikhoyo kwi-United States: propylthiouracil (PTU) kunye ne-methimazole. EUnited States, i-methimazole ithathwa njengeziyobisi ezikhethiweyo ze-antithyroid kwiimeko ezininzi.

I-Methimazole, ngamanye amaxesha kuthiwa yi-thiamazole, inqanda i-thyroid ukuba isebenzise i- iodine ukuvelisa i-hormone ye-thyroid. Ngokuqhelekileyo kuthathwa njengeditha kanye ngosuku.

Isilwanyana sisetyenziswe kwihlabathi jikelele. E-United States, i-Tapazole yiyona yedwa igama lomhlaza we-antithyroid ye-methimazole. Kukho inani labenzi bokuvelisa be-methimazole.

Tapazole

I-Tapazole yigama lomthi we- methimazole , isilwanyana esine -antithyroid esenziwe ngu-King Pharmaceuticals, Inc. I-FDA ivunyiwe iTapazole ngo-2000.

I-Tapazole Izithako : i-methimazole USP; lactose monohydrate; i-magnesium stearate; isitashi (ingqolowa); isitashi esandulela; ne talc.

Amandla afumanekayo : 5 mg kunye no-10 mg

I-Generic Methimazole (nguSandoz)

U-Sandoz, ilungu le-Novartis Group of Companies, wenza i-methimazole yama-generic. Yavunywe yi-FDA ngo-2001.

Sandoz Methimazole Izithako: i- methimazole USP; lactose monohydrate; i-magnesium stearate; isitashi (ingqolowa); ne talc.

Amandla afumanekayo: 5 mg kunye no-10 mg

I-Generic Methimazole (nguCedar Pharmaceuticals LLC)

I-Cedar Pharmaceuticals LLC abenzi be-methimazole yama-generic abasasazwa yi-United States Laboratories. Imvume ye-FDA ifumaneka ngo-2005.

I-Cedar Pharmaceuticals Methimazole Izithako: i- methimazole USP; actose monohydrate; i-magnesium stearate; isitashi; ne talc.

Amandla afumanekayo: 5 mg, 10 mg, 15 mg, 20 mg

I-Generic Methimazole (ngu-Activis Totowa)

I-Activis Totowa LLC abenzi bokuvelisa i-methimazole kunye ne-FDA imvume yafunyanwa ngo-2007.

I-Activis iMethimazole Izithako ze- methimazole USP; lactose monohydrate; i-magnesium stearate; isitashi esasisigxina; ne talc.

Amandla akhoyo: 5 mg kunye no-10 mg

I-Generic Methimazole (yi-Caraco Pharmaceutical Laboratories)

I-Caraco Pharmaceutical Laboratories, Ltd. ivelisa i-methimazole yesizwe evunyiwe yi-FDA ngo-2007.

I-Caraco Methimazole Izithako: i- methimazole USP; lactose monohydrate; povidone; talc; croscarmellose; i-magnesium stearate; nesitashi samabele.

Amandla afumanekayo : 5mg kunye no-10mg

I-Generic Methimazole (yi-Par Pharmaceutical Companies)

I-Phar Pharmaceutical Companies yenza i-methimazole yama-generic.

Izithako: i- methimazole USP; lactose monohydrate; i-magnesium stearate; isitashi sommbila; ne talc.

Amandla afumanekayo: 5 mg kunye no-10 mg

_Imithombo:

_{I-Med Med, iDaily Food and Drug Administration.}

_{I-FDA Inxibelelwano loKhuseleko lweNkunkuma: I-Box Boxed Warning kwi-Insecurity eyingozi kakhulu kunye nePropylthiouracil, uEpreli 21, 2010}

_{Ross, Douglas MD, "Ulwazi olunomonde: Izidakamizwa ze-Antithyroid," UpToDate . Kuhlaziywa ngokutsha: ngoNovemba 13, 2009}

Ingxelo eyongezelelweyo ngu: Leslie Blumenberg