Ukukhula kweThambo elingavumelekanga apho akufanele kube khona
I-osterification ye-Hetotopi igama elisetyenziselwa ukuchaza ithambo efom eweni apho akufanele ikhona khona. I-osterification ye-Hetotopisi ngokuqhelekileyo ithetha ukuba ithambo lifakwe ngaphakathi kweethambo eziluhlaza , kuquka i-muscle, ligaments, okanye ezinye iifom. Ngokuqhelekileyo isicatshulwa esithi "HO," i-heterotopic ossification inokuthi yenzeke nantoni na emzimbeni. Ithenda ye-heterotopic idlalwa emva kokuhlinzwa, ukulimala, okanye ngamanye amaxesha ngezizathu ezingaziwa.
Iimpawu zeHeterotopic Ossification
Uphawu oluqhelekileyo lwe-heterotopic ossification kukuqina kobambiswano. Uninzi lwabantu abahlakulela i-heterotopic ossification abakwazi ukuziva ithambo engavamile, kodwa qaphela ukukhula kwethambo ukufumana indlela yokuhamba ngokuqhelekileyo. I-bone ye-heterotopic ihlala ijikeleza ngokujikeleza okanye i-elbow joints, okwenza kube nzima ukuguqa kwezi ngxube. Ezinye iimpawu zingabandakanya ubunzima obunokuziva, ukukhubazeka kwendawo okanye intlungu.
Xa i-Heterotopic Ossification ivela nini?
I-osterification ye-heterotopy iyenzeka xa umzimba ufumana iimpawu ezixutywe, kunye neeseli zethambo ziqala ukudala ithambo elitsha ngaphandle kwesiguli esivamile. Umzimba uhlala wenza amathambo amatsha ukuze athathe indawo yethambo ngaphakathi kwegazi. Xa kuvela i-fate kwithambo, ithambo elitsha lenziwa ukuphilisa ithambo elonakalisiweyo. Kubantu abanesifo se-heterotopic bone, inkqubo efanayo iyaqhubeka, kodwa ngokuqhelekileyo ngenxa yezizathu ezingaziwa.
Inkqubo yokwenza amathambo amatsha kuthiwa yi-skeletogenesis.
Xa le nkqubo ivela ngaphandle kwethambo eliqhelekileyo kufuneka libe khona, umphumo kuthiwa yi-heterotopic ossification. Imiphumo ibangelwa kwiimeko ezingenakwenzeka. Kwezinye iimeko, ithambo le-heterotopic liya kuphawulwa kuphela kuba i-x-ray yenzelwe ukukhathazeka okungahambelani. Kwabanye, iziphumo zinganciphisa amandla omntu ukwenza imisebenzi elula, njengokuhamba.
Yintoni ebangela i-Heterotopic Ossification ukuba ivele?
Kukho izimbangela ezininzi ze-heterotopic bone formation. Ezi ziquka:
- Izimo ze-Genetic (ezifana ne-fibrodysplasia ossificans progressiva kunye ne-heteroplasia ene-osseous progression)
- Iinkqubo zokuphanda (kubandakanywa ukutshintshwa kwe-hip kunye ne- elbow fracture kunye nokuqhutyelwa kwe- optic break )
- Ukulimala kwentsholongwane okanye ubuhlungu bomgudu ( ukulimala kwengqondo kunye nokulimala komgudu )
- Ukulimala kwezemidlalo (i- myositis ossificans )
Ngaba Kukhona Unyango?
Ukunyangwa kwe-osterification ye-heterotopic kunzima, njengoko kuncinci kuqondwa malunga nokokubangela ukuba le meko ivele. Ngenxa yokuba kuncinci ukuqonda ukuba kutheni ithambo le-heterotopic lingazenza, kunzima ukwazi indlela yokukhusela ithambo elongezelelweyo ekubeni lenze.
Ukutshatyalaliswa kokutshatyalaliswa kwethambo le-heterotopic kunokwenzeka kwizigulane ezithethwe ngethambo le-heterotopic ngenxa yokuhlinzwa okanye ukuxhatshazwa (izigulane zengqondo kunye nesigulane sokulimala). Ngokuqhelekileyo, isincomo kukuba amathambo abo ase-heterotopic kufanele aqokelele ngokugcwele, oku kuthetha ukuba akukho thambo elongezelelweyo elenzayo. Ngelo xesha, utyando lungaqwalaselwa ukususa ithambo. Oku kuvame ukuqhutyelwa ukuvumela ukuhamba kwendibano ebanjwe iqhwaba ngenxa yendlela yokwenza amathambo.
Kwizigulane ezine-genetic disorder ezenze ukuba ithambo le-heterotopic lenze, utyando lonyango olungalunganga.
Enyanisweni, kwezi zi gulane, ukwenza utyando ukususa ithambo engavumelekanga kungalimaza imeko yonke.
Uphando lwenziwe ukwenzela ukuba ngaba ngaba kukho unyango lwemizimba ukuguqula ukubonakalisa iigeni ezibonwe kwizigulane ezine-ossification ze-heterotopic. Ezi zonyango zikwinqanaba lokuqala lophando.
Ngaba i-Heterotopic Ossification ingabanjwa ?:
Kwizigulane ezisengozini enkulu ekuphuhliseni i-heterotopic bone formation, kukho iindlela ezininzi zonyango ezisetyenziselwe ukuthintela ukuphuhliswa kwethambo elingaphezulu. Amachiza athile, kuquka amanani aphezulu angama-antisteroidal anti-inflammatory (NSAIDs), aboniswe ukunciphisa ukuphuhliswa kwethambo le-heterotopic.
Enye impikiswano yokuxhatshazwa kukuba kusetyenziswe unyango lwamayeza kwimizi enye ukuguqula iiseli ezivelisa i-bone excess. Ngamanye amaxesha ukusetyenziswa kwamafutha kusetyenziswa emva kokuhlinzwa okubalulekileyo okanye kwizigulane ezineembali zophuhliso lwethambo le-heterotopic. Ukunyangwa kwamayeza kunempikiswano, njengoko i-radiation ingabangela umonakalo wezinto kunye nokulibazisa ukuphilisa apho kwenziwe unyango.
Kwixesha elidlulileyo, abanye oogqirha basebenzisa i-radiation ngethuba lokutyunjwa kwe- hip ukuguqulwa kwethambo le-heterotopic alizange libe yinto engxaki yokuhlinzwa. Okwangoku, ngaphandle kokuba isigulane sithathwa njengengozi enkulu ekuphuhlisweni kwethambo le-heterotopic bone, unyango lwe-radiation alukhuthazwa.
Imithombo:
Kaplan FS, et al. "I-Heterotropic Ossification" J Am Acad Orthop Surg ngoMashi / uEpreli 2004; 12: 116-125.
UHealy WL no-Iorio R. "I-Heterotopic Ossification Emva kohlobo lwe-Hip ne-Knee Arthroplasty: Izinto ezijongene nobungozi, ukukhusela kunye nokunyanga" J Am Acad Orthop Surg November / Disemba 2002; 10: 409-416.