Ezinye iimeko ziNokuthi zenze i-Autoimmune, i-Dymyelinating
Ngaba i- fibromyalgia ifana ne- multiple sclerosis (MS) kunokuba sicinga? Umgca oyingqalileyo wophando wenza ukuba kubonakale ngale ndlela, ubuncinane kwezinye iimeko.
Ukuqonda uphando kunye noko kuthetha ntoni, okokuqala kufuneka uqonde okufutshane malunga ne-MS.
Multiple Sclerosis Basics
I-MS ikholelwa ukuba isifo esizimele , oko kuthetha ukuba isistim somzimba saso siya ku-haywire kwaye sihlasela isahlulo sakho, sikholelwa ukuba siyi-pathogen kwaye kufuneka siyitshabalalise.
Kwi-MS, inkolelo ephezulu kukuba iimpawu zibangelwa yinto ebizwa ngokuba yi-demyelination , oku kuthetha ukuba isistim somzimba sitshabalalisa into ethiwa i-myelin.
I-Myelin yiseli ekhethekileyo eyenza i-sheath malunga neentsholongwane kwaye kuyimfuneko ukuba loo misonto isebenze ngokufanelekileyo. Kufana nokuxhoma kwimbane zombane. Iindawo apho i-myelin sheath ishatywayo kuthiwa izilonda.
Fibromyalgia & Demyelination
Ukufundwa kokuqala kwe-fibromyalgia kunye nokudemokelwa kwiphupha kuphuma kwiphepha leRheumatology ngo-2008, kwaye ukulandelelwa kwanyatheliswa ngo-2014 kwinqanaba leArthritis & Rheumatology .
Uphando lwe-2008 lucetyise ukuba i-subset ye-fibromyalgia iquka ukutshabalalisa ngokuzenzekelayo kunye ne-polyneuropathy (intlungu ebuhlungu besifo). Uthelekisa i-fibromyalgia kwisifo se-neurological esibizwa ngokuba sisifo esingapheliyo sokukhupha i-polyneuropathy, esoloko siphathwa nge-immunoglobulin (IVIg).
Enyanisweni, kweso sifundo, basebenzisa i-IVIg ukuphatha abantu kweli qela le-fibromyalgia. Kuyavunywa, kwakunomxholo omncinci kwaye abantu aba-15 kuphela baphathwe, kodwa abaphandi bathi abo bantu babenentlungu engathandabuzekiyo kunye novelwano kunye nokuphucula amandla, kunye nokuphuculwa okuncinci ekukhathala nokuqina.
Lo ngumzekelo omhle wokuba isifundo sokuqala sinokuthi sibe neempembelelo ezinkulu kwaye kunjalo sinomthelela omncinci okanye akukho nto. Ewe, abanye oogqirha basebenzise i-IVIg kwizigulane, kodwa kude kwindlela yokwanda kwonyango kunye nokudibanisa kwi-fibromyalgia cishe akuzange ixoxwe.
Ukukhawuleza phambili kwiminyaka emithandathu, kwaye ekugqibeleni sinesifundo esilandelayo esibonakalayo sokuqinisekisa ukufunyanwa kwangaphambili kunye nokuqhubela phambili. Kuxhaswa kwakhona ngomnye umsebenzi owenziweyo kwiminyaka embalwa edlulileyo.
Iziphumo ezintsha
Okokuqala, abaphandi bafuna ukuphonononga ukuba ukutshatyalaliswa kwemibhobho emikhulu (iintsholongwane ezinkulu), ezifunyenwe kwisifundo sangaphambili, kubangelwa ngokuzimela. Emva koko, babefuna ukuphonononga i- fiber neuropathy encinci , apho ezinye iingcebiso eziye zacetyiswa zibandakanya kwi-fibromyalgia.
I-fiber encinci ye-neuropathy inobungozi obubi kwizakhiwo zesikhumba, izitho, kunye neentsholongwane ezikuvumela ukuba uzive uncedo ukulawula imisebenzi ngokuzenzekelayo njengezinga lentliziyo kunye nobushushu bomzimba. Abaphandi banomdla kulo mgca wokubuza imibuzo ngenxa yokuba i-fiber encinci ye-fiber ngezinye izihlandlo idibaniswa nezilonda ze-demyelination kwi-fibers ezinkulu.
Bafumene izibonakaliso ze-fiber encinci ye-neuropathy, kuquka ukuvakalelwa kweemilenze ezantsi.
Kwavavanyelwa kwakhona ngabaphawu abaninzi bokusebenza komzimba kunye nomsebenzi wokuzimela.
Bathi bafumene izibonakaliso eziphezulu ze-fiber neuropathy, kwaye ngoko ke izilonda ezinkulu zefiber, kwimilenze yabantu abane-fibromyalgia. Bafumanisa ukuba ezi zikhombisi, ngokukodwa kwethole, zibonakala zidibene nommakishi wokusebenza komzimba okubizwa ngokuba yi-interleukine-2R.
Baphetha ukuba i-fiber encinci ye-neuropathy inokuba negalelo lentlungu, kwaye ezinye iintlungu zethu zivela kumsebenzi womzimba womzimba, onokubandakanya ukuzimela.
Ukubeka Kwimixholo
Olu hlolo olulandelayo luza ngexesha apho umdla woluntu uphando lwe-fibromyalgia lubonakala uguquka kwi-fiber encinci ye-fibroyalysis, ukuvuvukala, kunye nokwenzeka komntu.
Kuthatyathwe kumongo, lo msebenzi uneza umfanekiso ovelayo wokuba siye sonakalisa imisipha emva kwayo yonke into, ukuba iinkqubo zethu zeentlanzi zithinteka ngokuqinisekileyo, kwaye ukuzimelela komzimba okanye omnye umbandela wokuzikhusela osebenzayo.
Le nto yayisisifundo esincinci, kodwa inyaniso yokuba ibenzileyo ngaphambili kwaye ibonakala i-gel kunye nezinye iziphumo ezithandwayo zithetha ukuba kuya kuba nempembelelo enkulu kunokuba yandulela. Okona kuncinci, kubonakala ukuba lo mgca ofanelekileyo wokufunda omele uqhubeke.
Uphando olwenziwe kwiNzululwazi yezoNyango lwezoNyango , lwapapashwa ngo-2014, lwafumanisa ukuba abantu abane-MS banamazinga aphezulu kakhulu e-fibromyalgia kunabantu bonke. Oku kunokwenza umququzelelo wokufanisana kwiindlela ezisemgangathweni zomsebenzi.
ILizwi
Ukufunda ukuba imeko yabo ifana ne-MS ingaba nenzuzo yangempela kubantu abane-fibromyalgia. Okokuqala, abaninzi abantu bayazi ukuba yiyiphi i-MS kwaye bayayihlonipha njengemeko ebalulekileyo. Oku kungakhokelela ekumkelekeni koluntu kunye nokwamkelwa kwehlabathi jikelele kwizonyango. Oko ke, kunokukhokelela ekuphandeni kongeza.
Okwesibini, inokubonelela ngeendlela ezintsha zonyango kwi-fibromyalgia phakathi kweyeza ezisekwa kwi-MS.
Ukufana kufana nengqiqo, kuba iimeko zombini zinokubandakanya iilora kunye nokukhutshwa kunye neempawu zifana kakhulu. Kusenokwenzeka ukuba siya kuqhubeka sifunda ngakumbi malunga nesi sihloko kwaye izinto ezinokubakho ziza kuvela kuyo.
> Imithombo:
> I-Caro XJ, i-Winter EF. Ubungqina bentsholongwane engavumelekanga ye-nerve fibreyalgia kwi-fibromyalgia: impembelelo kunye ne-immunological implications. Arthritis & rhuematology. 2014 Julayi; 66 (7): 1945-54. i-doi: 10.1002 / ubugcisa.38662.
> I-Caro XJ, i-Winter EF, i-Dumas AJ. Izigulane ze-fibromyalgia zifumene iziphumo ezibonisa ukunyuka kwesifo sokudumala kwe-polyneuropathy engapheliyo kwaye kubonakala ngathi iphendula kwi-IVIg. Rheumatology. 2008 Feb; 47 (2): 208-11. i-doi: 10.1093 / i-rheumatology / kem345.
> Clemenzi A, Pompa A, Casillo P, et al. Ubuhlungu obungapheliyo kwi-multiple sclerosis: ngaba kukho i-fibromyalgia? Isifundo sokuqwalasela. Uhlolo lwezesayensi. 2014 Meyi 9; 20: 758-66. I-doi: 10.12659 / MSM.890009.