Xa Umntwana Wakho Unesifo Sesisu
Ukuba umntwana wakho usandul 'ukona kwimeko yexakeko ngenxa yokuba wayehlanza aze aphelelwe amanzi, unokunikwa i dose yeZofran (ondansetron). Unokuzibuza ukuba kutheni le nkunkuma esetyenziselwa isicupuchelelo kwi-chemotherapy yomhlaza isetyenziswa kubantwana abanesifo somkhuhlane. Kuye kwinto eqhelekileyo kwindawo yokuphucula i-gastroenteritis (isifo somkhuhlane).
Zofran vs. Phenergan
I-Phenergan (promethazine) isoloko isetyenziselwa ukulawula isicupunu kunye nokuhlanza, kodwa ngowama-2006 i-FDA icebisa ukuba ingasetyenziselwa abantwana abangaphantsi kwe-2. Eliyeza lenza umngcipheko wokubangela ukuphefumula okanye ukuyeka ukuphefumla kwiintsana nakancinci. Kubantwana abadala, i-Phenergan idla ngokubangela ubuthongo obuninzi babantwana abathandanga ukuyisebenzisa. Nangona umntwana wakho engasayi kuhlanza, ukuba ulele kakhulu ukusela xa sele enegciwane lesisu, uya kuba esele adibene.
UZofran unesilumkiso sakhe, nangona kunjalo, ubuncinane kwimilinganiselo ephakamileyo eyayisakuba yinkwenkwezi kunye nokuhlanza ehambisana ne-chemotherapy. Oku kulandele isifundo esifumene ukuba i-do-32 yomlenze enye ingathintela isigqi senhliziyo, ekhokelela ekuphumeni kwexesha le-QT. Kodwa le dose, nangona kunjalo, ayisekho kwaye iphakame ngaphezu kwe-2 milligrams ukuya kuma-milligriki ayi-8 apho abantwana kunye nentsha baqeshwe.
I-Zofran yeSifo seSisu
Nangona iZofran ivunyiwe kuphela ukukhusela isicupunu kunye nokuhlanza izigulane malunga nokunyuka kwamakhemikhali okanye ukuhlinzwa, amaninzi amachiza anikezelwa -ilebula kwezinye iimeko. Kule meko, kukho uphando olunzulu olubonisa ukuba iZofran inokukunceda ekuphatheni nasekukhuseleni ukuhlanza okunxulumene ne-gastroenteritis.
Uhlolo lweCochrane lweziphumo luphelile ukuba i-ondansetron yomlomo yasiza abantwana nabaselula ukuba bayeke ukuhlanza nokunciphisa isidingo sokungeniswa kwamanzi kunye nokwamkelwa esibhedlele. Ucwaningo luka-2014 luthi uZofran unikezwe kwisiqingatha sabantwana abaneesifo somfuyo abaye bavakashela igumbi lexakeka kwi-US. Uphando luphelile ukuba oogqirha kufuneka bagxile ekunikezeni izidakamizwa kubantwana abasemngciphekweni wokungcola, abakwazi ukugcina umlomo ukusetyenziswa kwamanzi, kwaye unokufuna iimanzi ezixhamlayo.
Zofran kubantwana
Ngelixa ezininzi iingcali zithola uZofran uncedo kwigumbi lexakeka ekukhuseleni nasekunyangeni ukuhlanza kwi-gastroenteritis, isifo sakho sezingane asikwazi ukuyibeka kwisigulana. Izikhokelo zokusebenza ngoku, kuquka ezo zivela kwi-American Academy ye-Pediatricians, ungacetyisi ukusebenzisa amayeza ukuyeka ukuhlanza. Akukho ziphando zophando ezisekela ukuba kusebenza kule meko njengoko zonke izifundo ziyenziwe kwimeko yegumbi loxakeka. Ukuba uphando olongezelelweyo lusekela, mhlawumbi oogqirha bayayisebenzisa ngakumbi abantwana abaneentsholongwane zesisu.
> Imithombo:
> I-Cheng A. Ukusetyenziswa kwesebe ngokukhawulezileyo komlomo we-ondansetron ukwenzela ukuhlanza okunxulumene ne-gastroenteritis ezinxulumene nabantwana kunye nabantwana. IiPediatrics & Health Health . 2011; 16 (3): 177-179.
> I-Fedorowicz Z, uJagannath VA, uCarter B. Antiemetics ekunciphiseni ukuhlanza okuhlobene ne-gastroenteritis enzima kubantwana nakwishumi elivisayo. I-Cochrane Database yeeNkqubo eziPhezulu . Julayi 2011. Ithenda: 10.1002 / 14651858.cd005506.pub5.
> Freedman SB, Hall M, Shah SS, et al. Impembelelo yokunyusa i-Ondansetron Usetyenziso kwiziphumo zeeKlinikhi kwi-Children With Gastroenteritis. JAMA Pediatrics . 2014; 168 (4): 321. i-doi: 10.1001 / i-jamapediatrics.2013.4906.