Azelastine HCL kunye neFluticasone Propionate
I-Dymista (azelastine kunye ne-fluticasone) inxulumene neyeza zecray spray ene-azelastine hydrochloride (0.1%) kunye ne-fluticasone propionate (0.037%). Iza kumlinganiselo we-micrograms ezingama-50 (mcg) ngefrayimu kwaye isetyenziselwa ukunyanga iimpawu ezinxulumene nokunyuka kwexesha.
Ngenxa yokuba i-Dymista iyinhlanganisela ye-nasal spray, iimpawu ezinxulumene neengxaki zonyaka ziye zenziwa ngokusebenzisana neendlela ezimbini ezahlukeneyo emzimbeni.
Icandelo lokuqala kwi-Dymista, azelastine, ngumntu ongu-H1. Olu hlobo lweyeza luvimbela imiphumela ye- histamine kuwo wonke umzimba kwaye unceda ukunciphisa ukukhululwa kwe-histamine. Imbali kunye nabanye abalamlamli ngaphakathi komzimba bancedisa ekuphenduleni, ngokukodwa ukuvuvukala. Ngokunqanda i-histamine, i-Dymista inokukwazi ukunciphisa iindinyana zamanxeba ezivakalelwayo "ezizenzekelayo" ezinxulumene nokuvuvukala. I-Azelastine inceda ekuphuculeni ukunyakaza kwe-cilia (iincinci ezincinci ezihamba nomzila wokuphefumula) kwindlela ohamba ngayo, okunceda ekuphuculeni ukuthuthwa kwe-mucus.
Indlela yesibini eyenziwa yi-Dymista inceda ukukhulula iimpawu ezinxulumene neengxaki zonyaka ngenxa yecandelo lesibini lentsebenziswano ye-nasal spray, i-fluticasone. I-Fluticasone yi-corticosteroid, eyona nto ingumxholo wokwenziwa kwe-hormone ye-adrenal ngokwemvelo, i-cortisol. I-Corticosteroids inceda ukukhawulela imithana yegazi kunye nokunciphisa ukuvuvukala kwisigxina somnxeba xa sisetyenziswe kwifom yefrayimu.
Zenzo zombini zenza uncedo ekunciphiseni ukuxinana okuhambelana nokunyuka kwexesha. Umqathango othiwa ukudibanisa ukuxhamla kuhambelana neentambo zamanzi eziqukethe i-cortisone, nangona kunjalo, ngoko kufuneka uxoxe nale mngcipheko nodokotela wakho ngaphambi kokusebenzisa i-Dymista.
Indlela yokusebenzisa i-Dymista
I-Dymista yinto nje yokusetyenziswa njengesipopu esiswini.
Ngethuba lokuqala oyisebenzisayo uya kulufuna ukubeka phambili ipompo yefrayishi ngokucinezela amaxesha angama-6 de ubone i-spray. Mhlawumbi ufuna ukuphinda le nkqubo ukuba awuzange usebenzise i-Dymista nasal spray kwiiveki ezi-2.
Iingcebiso zokusebenzisa i-Dymista:
- Gubha ngobumnene i-Dymista nasal spray bray.
- Kubalulekile ukuvuthela impumlo yakho ukuze ucoce iipasti zakho zamanqaku kwiziphumo ezilungileyo.
- Gxotha intloko yakho phantsi ngenkcenkceshe yakho ekhaleni.
- Qinisekisa ukugcina intonga ye-nasal spray 1/4 ukuya kwi-intshi ye-intshi kwiipumlo zakho ngelixa uhlambalaza.
- Ibhotile kufuneka ihlale ilungile xa iphosa.
- Vala enye i-nostril uze uphendule ngokukhawuleza emva kokuba ucinezele ipompo.
- Gwema ukutshiza umgca wengqumbo yakho yamanzi phakathi kwamaqanda akho eziphumo ezilungileyo.
- Sichitha elinye iqela ngendlela efanayo.
- Emva kokusetyenziswa, uya kufuna ukususa phezulu komfaki sicelo uze ufake indawo yefowuni.
- Gwema ukudibanisa kwamehlo - ukuba uqhagamshelwano lwamehlo lusehlotshiswe amehlo kumzuzu engama-10 okanye ngaphezulu. Funa unyango xa kunesidingo.
I-Dymista Side-Effects
Iziphumo eziqhelekileyo ezichaphazelekayo eziphathelene nokusetyenziswa kweDymista ziquka:
- iguqulwe ingcamango
- intloko
- izimpumlo
- kulala
I-Dymista ingabangela ubuthongo, ngoko kufuneka uqaphele xa usebenza naluphi na umatshini okanye uqhube ukuqhuba ukuba wazi ukuba umzimba wakho uphendule njani kumachiza.
Kufuneka uphephe ezinye izidandlululo ezifana notywala xa usebenzisa i-Dymista njengoko oku kungonakalisa izinga lokudibana okanye ukulala. Ngenxa yokuba i-Dymista iqukethe i-fluticasone, eyi- corticosteroid , ukusetyenziswa okungapheliyo kunokukhokelela ekukhutshweni kwenkqubo yakho ye-adrenal. Landela imiyalelo yokugulisa ugqirha ukuba ufuna ukuyeka le mayeza. Ukuncitshiswa kunokwenzeka ukuba kwenzeka xa usebenzisa le mayeza kunye ne-Prednisone eneqondo lama-milligrams (mg) okanye ngaphezulu. Icandelo le-fluticasone ye-Dymista linokubangela ukulibaziseka kwiilonda zokuphilisa kwindinyana yakho yangasese kwaye kubangele ukwanda okanye ukwandisa ixesha lokusuleleka.
Ukuba unembali yokunyanzeliswa kwe-intraocular, i-glaucoma evulekileyo, okanye i- cataracts , kufuneka ubone i-ophthalmologist kwaye uxoxe nale ngxelo ngaphambi kokuba usebenzise. Ukuba uhlakulela nayiphi na umbono utshintsho ngexesha lokusebenzisa i-Dymista, kufuneka uyeke ukusebenzisa i-spray spray uze uxoxe ngokuqhubekayo kunye nogqirha kunye ne-ophthalmologist.
Ngaba i-Dymista Interfere kunye namanye amayeza?
Ubuninzi beentsebenziswano kunye neDymista zihlobene nemichiza ephazamise inkqubo yakho yomnatha okanye umsebenzi wengqondo. Ezi ziquka i-antihistamines, i-anti-depressants, iigulana zokulala kunye namanye amayeza angabangela ukugungqa njengomphumo wecala. Hlola nodokotela wakho xa uqala amachiza amatsha.
Ngaphambi kokuthatha iDymista
Ngaphambi kokuba uqale iDymista, kufuneka ubone ugqirha wakho ukuba ahlaziye imbali yakho yezobugqirha kunye nokuhlaziya iimichiza zakho zangoku. Ngokukodwa, ugqirha wakho uya kufuna ukwazi ukuba unayo izilonda ekhaleni lakho, njengoko ukulibazisa ukuphulukiswa kungenzeka ngokusetyenziswa kweDymista. Ukuba uceba ukukhulelwa kufuneka ahlole ukuba okanye ukusetyenziswa kwe-Dymista kufuneka kugwenywe njengokuba i-Pregnancy Category C imithi.
Sebenzisa kuphela i-Dymista phantsi kokuvunywa ngogqirha kunye nokuvavanywa ukuba ungagciniwe, okanye awuzange ube nenkukhu okanye imasisi kuba iDymista inokunyusa ukwanda kwezi zifo.
> Imithombo:
> UpToDate.com. Azelastine kunye neFluticasone: Ulwazi lweziyobisi.