I-SAVI Isixhobo sokunciphisa i-Cancer Breast Recurrence

by Pam Stephan

Iimveliso kunye ne-Cons of the SAVI Brachytherapy Device kwi-APBI

Ukuba i-radiation yakho ye-oncologist ikhuthaze i-SAVI ye-brachytherapy isicatshulwa kwisibeleko sakho sebele , mhlawumbi unemibuzo eninzi. I-APBI yenyathelo elithile elikhawulezileyo elikhethiweyo (i-APBI) yindlela enye ukuba unayo i- lumpectomy yomhlaza wesifuba. Yintoni omele uyayizi malunga nale divayisi kwaye ungayilindela ntoni kunyango? Iphumelela njani le ndlela ngokuphathelele kwiindidi zemveli zonyango? Makhe sithethe malunga nendlela i-SAVI brachytherapy isebenza ngayo, kunye neenzuzo ezinokuthi uziqwalasele xa usenza isigqibo sakho.

Injongo emva kwonyango ye-radiation emva kwe-lumpectomy kukunceda ukukhusela ukuphindaphinda komdlavuza wakho webele. Ngokwenene ukuphindaphinda komhlaza wesifuba ojongene nokufa kwabantu abaninzi kwisifo. Utyando olulondolozwayo lwebele lwe-lumpectomy luyinto engaphantsi kancinci kune-mastectomy kwaye luhamba kunye nokuphila xa nje kulandelwa unyango lweemitha ukubulala yonke into eyenziwa ngumhlaza webele. Into engafanelekanga yolu, nangona kunjalo, ukuba unyango lwe-radiation lonakalisa izicubu eziqhelekileyo. I-brachytherapy, okanye i-ray-internally-delivered radiation, yindlela ekhusela izicubu ezinempilo ngenkathi unyanga izicubu ezijikelezayo.

Ukulwa neCanscer Breast From Within

Yintoni i-SAVI brachytherapy yomhlaza webele? I-Credit: Istockphoto.com/Stock Photo © Stephanie Zieber

Ukunyangwa kwamayeza omhlaza wesibeleko sebele kunganikwa i-radiation yangaphandle okanye yangaphakathi.

Imisebe yangaphandle, ebizwa ngokuba yi-full-breast-irradiation (WBI), iyayiphatha yonke ibele ngaphandle, ngokujolisa kakhulu kwi-x-rays kwi-tumor.

Ubunzima bentrashytherapy , ebizwa ngokuba yi-brachytherapy ye-interstitial, ifom yangaphakathi yomlambo osebenzisa i-catheters ekhethekileyo (iibhabhu ezincinci) ukuhambisa i-radiation esuka ngaphakathi kwebele yakho kwi-tumor cavity kunye nesixa esincinci seesisipha.

Ukukhawuleza kweNtsholongwane yeBreast Irradiation (APBI)

Siza kuthetha nge-SAVI ifowuni yokukhawuleza ukuxiliswa kwebele ye-breast (APBI), kodwa kubalulekile ukuba uqaphele ukuba i-APBI inokwenziwa njengeyifom ye-radiation yangaphandle, okanye njengendlela ye-radiation yangaphakathi okanye i-brachytherapy njenge-device ye-SAVI.

Ngaphandle kwexesha, ukuxiliswa kwesifuba esisodwa kwangaphandle kwenziwa, nangona kunjalo ikakhulu kumaziko omhlaza nawo enza i-brachytherapy APBI. Ukuthelekiswa nentsholongwane epheleleyo yonyango lwe-radiation yangaphandle, uphando lokuqala lufumene ukuba i-APBI yangaphandle idibene nomngcipheko ophezulu wokuphindaphinda kwendawo kunye nomngcipheko omkhulu womhlaza wesiqhelo esitsha okhulayo esifubeni esifanayo njengomhlaza wokuqala.

Ngokumalunga ne-external radiation ye-radiation yangaphandle, i-APBI yangaphandle ibonakala ihambelana nomphumo osonxisayo wezonyusa kodwa unobungozi obuncinane bekhumba. Kwizifundo, i-APBI yangaphandle yayisetyenziswe ngokuqhelekileyo kubasetyhini abaneengcambu ezincinci ezingenayo i-node negative, receptor positive, ne-HER2 negative.

Kwinqanaba elihle, i-APBI inokuqhutywa ngexesha elifutshane kakhulu, ukuphuculwa ngokweqile kokukhathala kunye nomgangatho wobomi.

Nangona ukusetyenziswa kwe-APBI yangaphandle okwangoku kujikelezwe ngquzulwano, amanye amaziko amakhulu omhlaza afunda iindlela zokuphucula ulawulo lwendawo kunye nohlobo lwamayeza.

Makhe sijonge ngaphakathi (i-brachytherapy) i-APBI kunye ne-SAVI ifowuni.

I-SAVI ™ iHlasetic Breast Irradiation (APBI)

I-SAVI Radiation Applicator. Imboleko: Umfaki-sicelo we-SAVI - Ifoto © Cianna Medical

I-SAVI, eyayiyi-FDA evunywe ngo-2006, isistim se-radiation sesifuba esinokuthi sibe yinto eyenziwe ngokusemthethweni kwi-lumpectomy cavity yakho, kungakhathaliseki ukuba yeyiphi imo okanye ubungakanani.

Le fowuni yisithambiso samathambo amancinci, amancinci. I-SAVI ifakwe kwi-incision encinci, kwaye i-catheter isanduku iya kwandisa ngokufanayo, kodwa i-design yayo eyingqayizivele ivumela ukuba ivule ngendlela ehambelana nobukhulu kunye nesimo se-tumor cavity.

Umthamo we-radiation unokulawulwa ngabanye kwi-catheter nganye, ukuvumela ukujoliswa ngokuchanekileyo ngu-oncologist. Esi sixhobo sinokuzikhethela ngokwedlula i-bhaluni ye-balathon ye-catheter ifowuni ukwenzela ukuba abasetyhini abancinci bangakwazi ukufumana olu hlobo lonyango.

Into onokuyilindela kwi-SAVI Applicator

I-SAVI Radiation Applicator Placement. Iimboleko: Ukufakwa - Ifoto © Cianna Medical

Udokotela wakho ogqirha unokufaka umfaki-sicelo we-SAVI ngexesha le-lumpectomy yakho, okanye ingeniswa ngexesha lotyando olulodwa. Kufuneka kuphela ukubethelwa okuncinci, ukuvumela ukuba i-compact catheter isitampu ibekwe ngaphakathi kwebele. Indawo yokuxhamla iya kugcinwa ngokugqoka, kwaye inxalenye yomgca wecatter nganye iya kwandula ngaphandle kwebele yakho de kube unyango lwakho lugqibe.

I-catheters iguquguquke kwaye ilula, ngoko kufuneka ikhululekile kuwe kwiintsuku ezi-5 ukuya kwezi-7 zemitha. Ukuguqulwa kwendawo yakho kuya kutshintshwa kabini ngemini ngethuba, kwaye kufuneka ligcinwe lome. Ukukhusela izifo, unokunikezwa ngamayeza okuthatha.

Kule fowuni imbewu encinci ye- brachytherapy (ama-pilets e-radioactive nganye malunga nobukhulu be-ngqolowa yelayisi).

Ukunyuswa kwamafutha ngexesha lokunyanga

I-SAVI Radiation Applicator Ukukhetha. Inkokhelo: Ukuzikhethela - Ifoto © Cianna Medical

Uza kuxela kwisibonelelo sakho se-radiation oncology kabini ngosuku ngemini yesi-5 ukuya kwi-7, ukufumana unyango. Cwangcisa ukuchitha imali malunga nemizuzu engama-30 ukutyelela nganye; malunga nemizuzu emi-5-10 yokuqeshwa kwakho kuya kusetyenziswa ixesha lokunyanga kwamayeza. Iqela lakho le-radiation oncology liyakwenza ukhululeke, kwaye uqhagamshelane nomfaki-sicelo wakho we-SAVI kumthombo we-radiation.

Ngethuba lonyango ngalinye, umthombo we-radiation uthunyelwa nganye kwikhethri enye ngexesha. Inani elithile leemitha eziza kukhutshwa ngamaphuzu ahlukeneyo kunye nobude bekhomitha nganye. Oku kukunika i-dose efanelekileyo kwiisishu ezichaphazelekayo, kwaye ukhuselo oluphezulu lwezitho zenyama ezijikelezayo.

Ukugqiba umbane kunye nokususa i-SAVI Applicator yakho

ISaviation Radiation Applicator Removal. I-Credit: Ukususwa - Ifoto © Cianna Medical

Emva kokuba unyango lwakho lokugqibela lwamayeza, i-oncologist yakho ye-radiation ingasusa idivayisi ye-SAVI. Kufuneka kuthathe malunga nemizuzu emibini ukususa ifowuni, ukucoca isayithi lakho lokungena, kwaye uvale isikhumba ngamacwecwe okubamba. Ibhanki okanye ukugqoka kufakwe phezulu, kwaye uya kukhululeka ukuya. Qiniseka ukuba uye ekutyeleleni kwakho ukulandelelana, ngoko ugqirha wakho unokubona ukuba ukukhangela kwakho kuyaphilisa ngokufanelekileyo.

Impumelelo

Umhlaza webele. INgxowa-mali: i-Chicago Tribune / i-Contributor / Getty Izithombe

Ekubeni isantya se-breast accelerated partial irradiation (i-brachytherapy okanye i-APBI) yavunywa kuqala ngo-2002, oogqirha baye bafumanisa ukuba le nyeza inika izinga eliphezulu lokulawula isisu kubadlali abanomdlavuza wesibeleko, kunye nabani abafanelekileyo abafanelekileyo ukuba basebenzise.

Xa kuthelekiswa ne-irradiation yonke yobisi ekhokelela kwi-2 pesenti imfuno kamva yesigxina, i-APBI ibangele izinga le-mastectomy ye-4% kuphela. Isixhobo se-SAVI brachytherapy sibonakala sisebenza kakuhle xa siqhathaniswa nezinye izinto ezikhoyo.

Breastytherapy Benefits

Breast Radiotherapy. Ikhredithi: BSIP / Umxhasi / i-Getty Izithombe

Xa ukhetha uhlobo lolwaphulo lwe-radiation, lunokuba luncedo ukubala uluhlu kunye neempembelelo zonyango ngalinye. Ngokuqinisekileyo, i-pros and cons cons are not of importance in the same size, kwaye ungagqiba ukukhetha unyango oluneentlungu ezingaphezu kweendlela. Ezinye zeenzuzo zebrain brachytherapy ziquka:

Ukulimala kwimizimba enempilo. Isilumkiso esiswini sonke (i-radiation yangaphandle) sichaphazela izicubu ezinobungozi kunye nomhlaza wesininzi kwaye kunokubangela iziphumo zecala kwizicubu ezinempilo. Ubunzima bentrashytherapy yenzelwe ukudala umonakalo omncinci kwizicubu ezinempilo.
Ukuphindaphinda kwonyango. Zonyango zonke zonyango zonyango zidlalwa rhoqo ngoMsombuluko ukuya kuLwesihlanu malunga neeveki ezingama-6. Ngesibindi sebele, unyango luyakuthi luzaliswe kwisithuba se-5 ukuya kwe-7. Ubushushu bebhedlele buchaphazela inani elincinci lesisifuba sesifuba kunye nokuhambisa i-dose ekujoliswe kuyo kwi-lumpectomy site.
Ixesha lokubuyisela. Ixesha lokubuyisela lidla ngokukhawuleza kunye ne-brachytherapy yebele kunesilumkiso esisodwa sebele.
Imiphumela. Ngokuqhelekileyo, iimiphumo ezinjengokukhathala ziyancinci kunye ne-breast brachytherapy.

Iingxaki ze Breastytherapy

Kanye njengoko kukho izibonelelo zesifuba sebele, kukho ukungahambi kakuhle. Ezi ziquka:

Ingozi yokuphindaphinda umdlavuza webele. Njengoko kuphawulwe phantsi kobuchule, umngcipheko wokuphindaphinda umdlavuza webele uya kuphakama kakhulu kunye nebele yebele. Oko kwathiwa, akukho nangobu bungqina bokuba le nqanaba ephezulu yokuphindaphinda inefuthe kwiziphumo.
Ingozi yokusuleleka. Ngenxa yobuninzi beethubhu ezingena esikhwameni sakho, umngcipheko wosuleleko uphakamileyo kuneemitha zangasese zangaphandle, nangona zincinci.
Thuzelo. Abanye abantu bayifumana idivayisi ayinakulungeleki.
Imiphumo emihle. Ixesha elide lezonyango kunye nemiphumo emva kancinci inokuba yinto ephakamileyo kunye nebele ye-breast brachytherapy, nangona kubonakala kunobuncitshisi obuncinci (ubuncinci ithuba lokubomvu kunye ne-rashes).
Ukufumaneka. Ulwaphulo lwe-radiation lwangaphandle lufumaneke kakhulu kunokuba i-brachytherapy yebele.

Ngaba i-SAVI iyatholakala kum?

Umfazi kwiNtlanganiso. Ikhredithi: BSIP / Umxhasi / i-Getty Izithombe

I-SAVI yebrain brachytherapy iyatholakala kulo lonke elaseMelika, kodwa ayifumaneki kuyo yonke indawo yesifo somhlaza. Kuya kusebenzela amabele amancinci okanye amancinci, kodwa ezinye izinto zingenza ukuba zingabalulekanga kwabanye abantu. Hlola kunye nogqirha wakho malunga nokukhethwa kwe-breastproofed breast.

ILizwi kwi-Savi Brachytherapy kwiCanscer Breast

Zininzi iinketho ezitsha ziye zafumaneka ekuphatheni umdlavuza wesibeleko kwiminyaka yamuva. Ngelixa eli lihle, lithetha izigqibo ezininzi. Kubaluleke kakhulu kunanini ngaphambili kubantu abanomdlavuza ukuba bafunde ngesifo sabo kwaye badlale indima echaphazelekayo kwiqela labo lokukhathalela umdlavuza.

Yonke inyango inobungozi kunye neenzuzo, kwaye yintoni elungileyo ukuba umntu omnye angabi yinye. Yiba ngummeli wakho wokunyamekela umdlavuza wakho kwaye ukhethe unyango oluziva lukhululekile kuwe njengomntu ongeyena mntu. Ukwenza izigqibo malunga nokunyangwa kwengqondo yomhlaza yindlela enye yokuzihlonela ngonyango nangaphezulu.

> Imithombo:

> Gabani, P., Cyr, A., Zoberi, J. et al. Iziphumo zexesha elide ze-APBI nge-Multicatheter Interstitial HDR Ubuchopho bonyango: Iziphumo zeRejista ye-Registry Single-Institutional. Brachytherapy . 2017 Oktobha 28. (Epub ngaphambi kokuprinta).

> Hepel, J., Arthur, J., Shaitelman, S. et al. I-American Brachytherapy Society Ingxelo Yentsebenziswano ye-Breast Partial Breast Irradiation Ukusebenzisa i-Mutricatheter Brachytherapy. Brachytherapy . 2017. 16 (5): 919-928.

> Hickey, B., Lehman, M., Francis, D., no-A. Yabona. I-Breast Partial Irradiation For Cancer Early Breast Cancer. I-Cochrane Database yeeNkqubo eziPhezulu . 2016. 7: CD007077.pub3.

> Polgar, C., Ott, O., Hildebrandt, G. et al. Iziphumo eziphambene neziphumo kunye neZiphumo zokuChengisa i-Breastytherapy ngokukhawuleza kunye ne-Brachytherapy ye-Breastytherapy. Lancet Oncology . 2017. 18 (2): 259-268.

> Rana, Z., Nasr, N., Ji, H. et al. Ukuqhathaniswa kweziphumo zeDistimetric Ukusebenzisa i-Breast Partial Breed Irradiation kwi-Five Catheter Subtypes. I-Radiation Oncology . 2015. 10: 160.