Ukunciphisa ukubuyisela ukusebenza komzimba, kunciphisa umngcipheko weHIV
Umthwalo wentsholongwane kaGawulayo ngumlinganiselo we- HIV ejikelezayo kwigazi lakho ukuba unentsholongwane kaGawulayo. Umthamo wentsholongwane usetyenziselwa ukujonga ngendlela eyiyo ngayo izidakamizwa zakho ze- antiretroviral kwaye zikwazi ukuxelela oogqirha xa unyango lwakho lwenzekile okanye ungathathi amachiza akho njengoko kumiselweyo.
Injongo yeNtsholongwane kaGawulayo
Injongo yonyango lwe-HIV kukuthintela i-HIV ukuba iphinde iphindwe ukwenzela ukuba i-viral population ibe yinqanaba elingabonakaliyo.
Ukungabonakali kuthetha ukuba akukho ntsho longwane okanye ukuba intsholongwane ikhutshwe ngokukhawuleza emzimbeni wakho. Kuthetha nje ukuba akukho ntsho longwane ingabonwa ngokusebenzisa ubuchwepheshe bokuhlola obukhoyo. Xa ugqirha i-ART, intsholongwane iya kuhlala ibuye iphinde iphinde iphinde iphinde iphinde iphindwe kwakhona.
Kubalulekile ukuba uqaphele ukuba umthamo wegciwane lesandulela ngculaza ungahluka xa uvavanya igazi kunye nezinye izifo zomzimba. Umzekelo, umthwalo wentsholongwane engabonakaliyo egazini akuthethi ukuba awunakubonakala kwimbewu. Le ngqungquthela, eyaziwa ngokuba yi- viral shedding , inokunyusa umngcipheko wokusasazeka kubantu abaya kuthathwa ngenye indlela ukuba bangenayo i-virus.
Abantu abanomngcipheko wokungakhuselekanga kwintsholongwane kwingozi ye-immune system, ukulimala okushiya umzimba ukubonakaliswa kwiintsholongwane ezikhulayo.
Ukuhlolwa kweNtsholongwane yeNtsholongwane
Ngokuqhelekileyo, ugqirha wakho uzakuza kanye emva kweenyanga ezintathu ukuya ezintandathu ukulinganisa umthamo wakho wentsholongwane.
Uvavanyo olusandul 'uvavanyo olutsha lwe-viral test (HIV) oluthile lunokuthi lufumane umsebenzi we-viral njengezantsi ukuya kwiiikopi ezintlanu / mL kumaxwebhu angaphezu kwe-1,000,000 / mL.
Ngokwahlukileyo, iimvavanyo zentsholongwane yohlobo lwe-HIV zisebenzisayo nje zisetyenziselwa ukuqinisekisa ubungqina be-HIV kwaye zisetyenziselwa ukuvavanya iintsana kunye neentsana ezizalwe ngabafazi abane-HIV .
Ukutolika iziphumo zeVilal Load
Injongo yomthamo wentsholongwane ilula: iikopi ezimbalwa ze-HIV kwigazi lakho zibhetele.
Xa uqala unyango, uvavanyo lwemiqathango yesifo se-viral lunikezela ngamanyathelo okuqala apho iimvavanyo zangaphambili zithelekiswa. Ukulahla kweshumi ngokuphindaphindiweyo kumthwalo wentsholongwane kuthethwa njengesitya esisodwa. Ngokomzekelo, ukuba umthamo wentsholongwane wehla kwiiikopi ezingama-50,000 / mL ukuya kwiiikopi ezingama-500 / mL, isigulane sitsho ukuba sibe ne-log-log drop in viral load.
Ngokuqhelekileyo, ngokusetyenziswa kwezidakamizwa zeNTSHOLONGWANE KAGAWULAYO, umntu unokulindela ukuba abe nomthwalo ongenakulinganiswa nentsholongwane kwiphina kwiinyanga ezimbini ukuya kweziyisithoba. Nangona ijubane apho ukunciphisa ukufezekiswa kufumaneka khona, ludla ukuphuculwa kubantu abaye balibazisa unyango kwaye banomonakalo omkhulu wokuzivikela komzimba.
Silinganisela oku nge- CD4 count yomntu ebonisa ukuba mangaphi ama-CD4 T cells asele egazini. Umntu onomzimba oqhelekileyo unokuba nomaphi ukusuka kwi-500 ukuya kuma-1,500 amaseli / mL, ngelixa abantu abaneekhompyutheni ze-immune ezicwangcisiweyo bazoba ngaphantsi kwe-cell cell / mL.
Ukongezelela koko, ukuba umntu uye wakhula okanye wafumana ukuchasana naziphi na izidakamizwa ezimiselweyo, ukuxhomekeka kwintsholongwane ye-virus kungaphatheka kabi. Kwimeko enjalo, unyango luya kufuneka lutshintshwe emva kokuvavanya iimpawu ezibonisa ukuba yiyiphi imichiza okanye iziyobisi isigulane esinganyangekiyo.
Iinzuzo zeMthwalo eViyo engapheliyo
Injongo yonyango le-HIV kukugcina imithwalo engapheliyo ye-viral iminyaka emininzi engagcinanga kuphela ukhetho lwonyango kodwa iyanciphisa umngcipheko wesifo esibi ngama-53 ekhulwini .
Ukongezelela, ukugcina i-viral ingabonakali kakhulu kunciphisa ithuba lakho lokudlulisa intsholongwane kwabanye, isicwangciso sokukhusela esibizwa ngokuba yi- HIV njengokwenza ukhuseleko (iTraP) . Ucwaningo luye lwaxhasa ngokusisigxina ukusebenzisa i-TasP kwiimeko ezixubileyo (i- serodiscordant ), kubonisa ukuba kunokunciphisa umngcipheko malunga nama-96 ekhulwini.
> Imithombo:
> Cohen, M .; Chen, Y; McCauley, M. et al. "Ukuthintela usulelo lwe-HIV-1 ngonyango lokuqala lwe-antiretroviral." I-New England Journal of Medicine. Agasti 11, 2011; 365 (6): 493-505.
> AmaZiko eNational Health. "Ukuqalisa unyango lwe-antiretroviral unyango luphucula iziphumo zabantu abane-HIV." EBethesda, eMaryn; kukhutshwa ngoMeyi 27, 2015.