I-Epithelial basement membrane dystrophy (EBMD), eyaziwa nangokuthi isifo se-membrane yesifo sangaphantsi okanye i-map-dot-fingerprint dystrophy, yinto eqhelekileyo echaphazela inxalenye yangaphambili yeso. Iimeko zidla ngokuchaphazela abantu abangaphezu kweminyaka engama-30 ubudala. I-EBMD ngamanye amaxesha iyathula, ishiya abo bachaphazelekayo bayayiqonda imeko yabo. Abanye abantu abanesi sifo banokucaphuka ngokugqithisileyo okufutshane nokuba abanye banemiqondiso engapheliyo ebonakala ngathi isenza yonke imihla.
Ukuqonda i-EBMD
I-EBMD yintlupheko yeeseli ze -basal epithelial ezisecaleni langaphambili le-cornea. Ezi zisele ze-basal zinamathele kwisalathisi sesibini somlenze, ebizwa ngokuba ngumgca ka Bowman. Kwi-EBMD, iiseli ze-basal zenza izicwangciso ezingaqhelekanga zeminwe ezigxotha kwi-membrane. Ezi zicwangciso zenza ukuba iiseli ze-epithelial zikhululeke kwaye zingabambeleli kunye nomlenze. Ngaphandle kwezinye iinguqu ezenzeka phakathi kweeseli ze-epithelial, ezi tshintsho zinika ukubonakala kweemaphu, amachaphaza kunye neempawu zeminwe ngaphakathi kwe-cornea. Ezi zitshintsho zezibonakaliso zingabonwa kunye nokusetyenziswa kwesibane-biomicroscope yesibane .
Iimpawu ze-EBMD
Abantu abane-EBMD banokukhalaza ngala mpawu:
- Umbono wokutshintsha
- Umbono ongezantsi
- Intlungu ephakathi
Uninzi lwabantu abachaphazelekayo yi-EBMD banemibono eguqukayo ngaphandle kokuphazamiseka okukhulu. Nangona kunjalo, malunga neepesenti ezili-10 zineengqungquthela ezibuhlungu zokukhukhula komzimba.
Iziganeko eziqhelekileyo eziqhelekileyo zisoloko ziyiziphene ezincinci kummandla we-cornea ezenzeka ngezikhathi ezithile. Ezi mpazamo ziindawo zee-epithelial cells ezingekhoyo eziwela lula ngenxa yesifo. Ezi iiseli zikhululekile ngenxa yemigqaliselo yeminwe efana neyo, eyenza ukuba ilahlekelwe ukunyanzela kwi-membrane.
Iimpawu ziba zimbi xa zivusa okanye ngexesha leentsasa zasekuseni kuba iliso limila ebusuku kwaye iiseli ezingamkelekanga zibonakala zilula.
Ukuxilongwa kwe-EBMD
I-EBMD ihlala iphoswe ngamagqirha njengemephu ephulekileyo, icwecwe, kunye nokubonakala kwimizobo ebonakalayo kunye neemeko ezinokuzifihlakeleyo kwiimeko ezininzi. Nangona kunjalo, ekuhloliseni okufutshane, ezi zinguqu zitsho ziyafumaneka. Oogqirha bamehlo baya kuphulaphula ngokugqithiseleyo iimpawu zakho kunye nomlando jikelele wezonyango onokubanika izikhombisi. Idayi ekhethekileyo edayini nayo ingafakwa kwijiso lakho ukwenza utshintsho olusenyakatho lwezinto ezibonakalayo. Oogqirha banokwenza i-keratometry okanye i-colneal powpography enokulinganisa ukuma kwe-cornea. Ifilimu yakho yezinyembezi iya kuphinda ifundwe phantsi kwe-microscope ukulawula ezinye iimeko ezifana ne-keratoconjunctivitis sicca kunye nezinye izimo zamehlo ezibucayi.
Unyango lwe-EBMD
Unyango lwe-EBMD kubantu abangenayo impawu ebonakalayo kubandakanya ukusebenzisa iinyembezi ezinokwenziwa ngamaxesha amaninzi ngemini ukukhuthaza impilo yeli cell cell epithelial. Abantu abaneempawu ezibonakalayo baya kuxelelwa ukuba basebenzise ngokuphindaphindiweyo iinyembezi zokuzenza, kunye namafutha okugcoba amehlo ngaphambi kokulala.
Ukuba kukho imbali yeso elomileyo, ukukhutshwa kwamatyala kukhuthazwa kwakhona. Ukugqithiswa kwamatyala kufaka ukufaka i-collagen encinci okanye iplaski ye-silicone kwisitya somngxoworha wezonkqenkqiso kweso ukugcina iinyembezi zesigulane. Izixhobo eziphambeneyo okanye izigulane zinokuthi zibe yinxalenye yesicwangciso sonyango ukukhusela ukuma ngenxa yokuvela ebusuku.
Kwiimeko zeemeko ezinzima, oogqirha baya kuncoma i-hypertonic iso okanye i-ointment emini kunye nobusuku isisombululo setyuwa esibangela ukuphuma kwamanzi e-cornea, okwenza kube lula kakhulu. Oku kunceda iiseli ze-epithelial zihlala zixhaswe ngokuqinile kwi-cornea. Ngamanye amaxesha, oogqirha baya kusebenzisa ii-lens zokudibanisa ezithambileyo ukuze baphumelele i-cornea.
Kwiimeko apho isigulane siphumela khona iimeko eziqhelekileyo zokugulisa, oogqirha baya kunika amaconsi. Amaconsi aseCycloplegic angasetyenziselwa ukunciphisa intlungu kunye nokuphucula induduzo. I-Cycloplegic yehla iyanqabisa ukuvuvukala kwiso ngelixa elithile liphazamisa i-muscle ngaphakathi kweso elinokubambisana kunye kwaye lenze intlungu. Izinyembezi ezinobungozi, iinyembezi eziqhotyoshelweyo kunye neengqungquthela ezingabonakaliyo zesifo esingekho steroidal.
ILizwi
Ukuba awuphendulanga kakuhle kumachiza, inqubo ebizwa ngokuthi i-stroke stromal puncture inganconywa. Ukuguqulwa kwesigxina kwangaphambili kubandakanya ugqirha usebenzisa inaliti eyinyumba ukudala ii-punctures ezincinci eziwela i-membrane ephantsi. Oku kubangela ukuba izikrakra ezincinci zenze kwaye zikhawulezise ukuphilisa, kubangela ukuba iiseli ezijikelezayo zizinamathele kumlenze kangcono. Olunye uhlobo lwonyango yi-PTK. I-PTK, i-keratectomy ye-photorefractive kraatectomy, isebenzisa i-laser ukuze ibonakalise umphezulu we-cornea ukunciphisa iimpawu.
Umthombo:
Unonophelo loPhezulu lweNxalenye yangaphambili, uViwo lweSibini. I-Copyright 1995, Appleton & Lange.