Isifo esiphezulu se-celiac sisifo sokuxilongwa ngokukrakra: ngentsingiselo, ithetha unyango oluqhelekileyo lwesifo se- celiac - ukutya okungekho-gluten- kuye kwahluleka ukusebenza, kwaye kufuneka ufune ezinye iindlela.
Iindaba ezilungileyo, nangona kunjalo, ukuba le ceacac engathandabuzekiyo inqabile kakhulu. Kwiimeko ezininzi, ingxaki yakho ayiyiyo isifo se-celiac isifo sengqondo - kunoko, inani elincinci le-gluten ekudleni kwakho okanye enye imeko yonyango ibangela ukuba uqhubeke nempawu.
Nangona kunjalo, ukuba ugqirha wakho ulawula ezinye izizathu kwaye ekugqibeleni ufumanisa ukuba unesifo esiqhaqhaqhayo se-celiac, kufuneka wazi ukuba oogqirha banako ukuphatha amaninzi amatyala ngokuphumelelayo; unyango luya kuxhomekeka kukuphi uhlobo lwe-celiac yokugxekayo ohluphekayo kuyo, kunye nezinye iinkalo kwimbali yakho yempilo kunye nemeko.
Uhlobo lwee-Celiac Disease I-Refractory I-Determination Options, Inkambo
Kukho iintlobo ezimbini zesifo se-celiac esichasayo: Thayipha I kunye no-II. Xa ufumene unyango, ugqirha uya kukuxelela uhlobo olunalo. Ngokuqhelekileyo, Uhlobo I luqhelekile kwaye luphathwa ngokulula, kodwa uphando lwangoku luchaze iziphumo ezithembisayo zokuphatha udidi lwe-II.
Ngaphantsi kwamaxesha amaninzi, uya kunyangwa ngenxa yesifo se-celiac kwisifo esinqununu kunye nokujongana namava kunye nokubeka esweni imeko; ngenxa yokuba i-celiac engabonakaliyo inqabile, abaninzi be-gastroenterologists abazange baphathe iimeko phambi.
Unyango Mayokuqala NgeNkxaso Yokondla
Isifo esiphezulu se-ecliac singakhokelela ekulahlekelweni kwesisindo esikhulu kunye nokungondleki , nangona udla ukutya okunokulinganisela, okunokulinganisela kwe-gluten. Kungenxa yokuba umonakalo emathunjini akho amancinci, eyaziwa ngokuba yi -atrophy ehlambulukileyo, awuphilanga- naphezu kokutya kwakho ngokutya.
Ngoko ugqirha wakho unokuqala unyango ngokujonga izinga lomzimba wakho weivithamini, amaminerali kunye nezinye izondlo, kwaye unika inkxaso yokutya okuncedisayo ekuncedeni ukuphelisa ukungondleki kwakho. Ukufikelela kwi-60% yezigulane, olu xhasayo lusetyenziso olubizwa ngokuba yi-Total Parenteral Isondlo, esiyisisombululo sesondlo esithunyelwa ngqo kwi-vein, ngokugqithisa umzila wakho wesisu.
Ugqirha wakho unokuthatha isigqibo sokuzama oko kubizwa ngokuba kukutya okuqinileyo-ukutya okunesondlo okunika izondlo kwifomu ye-hypo-allergenic esele iphule phantsi kwiibhloko zazo zokwakha i-amino acid. Olunye uphando oluthile lufumanise ukuba izigulane ezilishumi elinesibhozo ezine-Type I zikhankanya izifo zabonisa ukuphucula kwi-intestinal villi ekudleni okunjalo; Abathandathu balabo bafumana ukuphucula kwiimpawu zabo.
Kwiimeko ezimbalwa ezibandakanya isifo sohlobo lwe-Type I, ukuxhaswa kwondlo kunye nesondlo esingaqinileyo se-gluten, unokufumana konke okufunayo ukuqala ukuphilisa. Kodwa abaninzi abantu bafumana unyango lweziyobisi.
Ulwaphulo lweMichiza ngohlobo lwamaQela ngokuqhelekileyo luquka iiSteroids
Okwangoku, unyango lweziyobisi lwe-celiac sifo luye lwagxila kwiipilisi ezenzelwe ukukhusela isistim somzimba wakho wegciwane lokuzama ukunika amathumbu akho ikhefu ekuhlaselweni kokuzimela okungapheliyo.
(Khumbula, akusiyo i- gluten ngokwayo eyenza umonakalo wamathumbu emzimbeni we-celiac - yindlela yakho yokumelana nomzimba omzimba ku-gluten. Kwiimpawu ze-celiac ezingenakuphikisa, isistim somzimba sakho saqhubeka nokuhlasela amathumbu akho, nangona kungabikho gluten ekudleni kwakho.)
Kuzo zombini I-Type I kunye ne-Type II isifo se-celiac isifo, ukwelashwa kweziyobisi zokuqala kwimizimba yesifo se-steroid ebizwa ngokuba yi-glucocorticoids. I-glucocorticoids ihlala isetyenziselwa unyango lwezinye iimeko ezizimeleyo ezifana ne-rheumatoid arthritis kunye nesifo sesibindi sokuvuvukala.
Esinye isicatshulwa esingasetyenziselwa unyango ngu-azathioprine, esebenza ngokuphelisa isistim somzimba wakho.
Abantu abane-arthritis enesifo esininzi esinamandla kunye nalabo abahlala kunye ne-azathioprine.
Uphando lubonisa ukuba abaninzi abantu abane-Type I isifo sengqondo esiyi-reflexory disease will go into remission -, ngamanye amazwi, bona iimpawu zabo zixazululwe kwaye amathumbu abo aqala ukuphilisa - ngokusebenzisa i-steroids, mhlawumbi idibene ne-azathioprine.
Uhlobo lwe-II I-Refractory Celiac Disease Inzima kakhulu yokuyiphatha
Izigulane ezinezifo zengqungquthela yesiGaba II zihlala zibona ukuphulukiswa kwiimpawu zazo ezivela kulolu hlobo lwezonyango zeermim, kodwa ngelanga, izithambo zabo ezingamathumbu aziphilisi kuwo, kwaye akubonakali ukuzikhusela kwifom ebulalayo engeyona iHodgkin i-lymphoma edibene nesifo esiqhekezayo .
Ezinye izilingo zamachiza ziye zavavanya isilwanyana esibizwa ngokuba yiCladribine - isistim esinamandla esinomdlavuza we-chemotherapy esisetyenziselwa i-leukemia-kwizigulane ze-II ezichasayo. Elinye ilingo, eliqhutyelwa eNetherlands, lafumanisa ukuba iCladribine yazinqabisa isifo ngokwaneleyo ukuba siyixolele kwizigulane ezingama-18 kwezi-32. Kodwa nangona le nkunkuma ibeka ezinye izigulane ukuba zixolelwe, kukho ukwesaba ukuba kungenakukuthintela ukungena kwe-T-cell lymphoma (EATL): loo nto inqabileyo, ebulalayo ye-lymphoma. I-EATL iphazamisa izigulane zeGaba II ngokungafaniyo.
Nangona kunjalo, oogqirha abathile sele baqalise ukusebenzisa iClaribine njengokhetho lwabo lokuqala lokunyanga isifo se-Celiac sesifo sohlobo lwe-Type II, kwaye bafumanisa ukuba banako ukubeka isigxina sezigulane zabo ukuba baxolelwe. Kwiliso elifanayo, ukusinda kweminyaka emihlanu kwizigulane ze-Type II eziphendule kwi-Cladrib unyango ngamaphesenti angama-83, xa kuthelekiswa nama-22 ekhulwini kulabo abangazange babone iziphumo ezintle kunyango. Okubaluleke kakhulu, akuzange kubonakale ukuba ukwanda kwimivuzo ye-lymphoma. Nangona kunjalo, ezi ziphumo zonyango azikabiwe.
Ekugqibeleni, kulabo abaneSifo II esicatshulwayo esibangelwa yizilwanyana ezingapheliyo, ababandakanyeka kuzo zonke ezinye izigulana, kuquka neClaribine, ubuncinane esisinye isikhungo se-celiac - esifanayo esashicilele iziphumo zolu vavanyo lweCladribine - uye wavavanya ukutshintshwa kwe-stem cell cell, inkqubo iiseli ezisetyenziseni zivunwa, zikhulile ebhodini kwaye ziphinde zatshintshwe emva kwakho emva kwe-high-dose chemotherapy. Le nkqubo inobungozi obuphezulu ngezinga eliphezulu leengxaki, kuquka ukufa.
Kwilingo elinye lezonyango ezibandakanya isifo se-calyptic reactory kunye ne-autologous stem cell transplant, iziganeko ezi-11 zezigulane ezingama-13 ziye zaphucula kakhulu phakathi konyaka we-cell stem. Omnye umntu wasweleka kwinkqubo yokutshintshwa ngokwayo, kwaye iibini kwisithathu sezigulane zisaphila iminyaka emine kamva. Esinye isigulane saphuhlisa i-EATL.
I-Treatment Celiac Yakho yoKhathaza ingase iqhubeke ixesha elide
Ukuthintela ukuphindaphinda kwesifo sakho se-reflexory disease, ungadinga ukuthatha i-steroids ngonaphakade. Kodwa ukusetyenziswa kwexesha elide le-steroids kubangela ubungozi balo (kubandakanywa ishukela ephezulu yegazi, amathambo amancinci kunye nomngcipheko ophezulu wokusuleleka). Ukongezelela, ukusebenzisa i-steroids ixesha elide kwandisa umngcipheko we-lymphoma-kwaye ke, izigulane ezingenakunyakazo zisesele ziphezulu kakhulu kunomngcipheko wolu hlobo lomhlaza.
Ngoko-ke abaphandi bahlola ezinye iindlela zokunyanga iziyobisi ezinokuthi zikhumbule izifo ze-celiac, eziquka imithi ebizwa ngokuba yi-mesalazine, isilwanyana esichasayo esasetyenziswa ngoku ukuphathwa kwezifo zesifo esivuthayo ezihlolwe kwizigulane zeTe. Uphando olongezelelweyo kule fomu engavumelekanga yesifo se-celiac kuya kukhishwa kwikamva elikufutshane.
Okwangoku, kungakhathaliseki ukuba unyango lwangexesha elide lunconywa ntoni kuwe, kuya kufuneka uhlale unxibelelwano olusondeleyo kunye nodokotela wakho kwaye ukhangele kuyo nayiphi na imiqondiso (njengokuhlaziywa kwesisindo somzimba kunye nesifo sohudo) ukuba isifo sakho se-reflexory celiac uphuma ukuxolelwa.
Imithombo:
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