Ndisebenzisa i Yaz, Yasmin, Beyaz okanye iSaferal - Yintoni endiyenzayo?
UMBUZO - NDIYAWASEBENZA IIPHILA ZOKUPHATHWA KWE-YAZ UKUBHALA, KUYA KUFUNEKA UKUFUMANA KUNYE NOKUBA NGOKWENKQUBO KWEENKQUBO ZENKQUBO YENKQUBO YOKWENZA IZIHLOKO EZIPHAKATHI NE-DROSPIRENONE PILLS?
Kwiminyaka yamuva nje, iipilisi ezidibeneyo ze -drospirenone ziye zaziwa kakhulu. Iipilisi zolawulo lokuzalwa ziquka i- Yaz , Yasmin, Beyaz , ne-Safyral. Ingxenye yesizathu sokuthandwa kwabo inxulumene nezinye zeenzuzo ezingenakuthobela.
Kubafazi abasenza isigqibo sokusebenzisa i pilisi malunga nokukhulelwa komzimba (ngaphezu kokukhusela ukukhulelwa, i-Yaz no-Beyaz baye bavunyelwa yi-FDA ukuba baphathe iimpawu zesifo sokugula esengumntu wokuqala kunye nokunyanga i-acne ye-acne . (0.4mg) ye-folic acid.
Enye into eyenza la mayeza alawulwa ngamapilisi ahlukeneyo kukuba aqulethe i- progestin drospirenone. Le progesin inokukhusela ama-hormone ahambayo alawula amanzi omzimba kunye ne-electrolytes. I-Drospirenone nayo inokukhokelela kumazinga aphezulu e-potassium kunye / okanye ukusebenzisana namanye amayeza enyusa i-potassium. Kukho nkxalabo yokuba ukusebenzisa iipilisi zokulawula ukuzala okuqulethe i-drospirenone kunokunyusa ingozi yakho yegazi eliqhathaniswa nokuqhathaniswa neepilisi zokulawula ukuzalwa eziqukethe iprogesin ehlukile.
---> Ngaphandle kolawulo lokuzala: Yaz noBeyaz
Kubalulekile ukubonisa ukuba zonke iipilisi zokulawula ukuzalwa zibeka umngcipheko wokuphuhlisa ama- blood clots .
Amacwecwe egazi ayenze emthanjeni onzulu emzimbeni abizwa ngokuba yi- vein thrombosis (DVT). I-DVT iyi-side control pilgrimp control side and can block the flow of blood. I- pulmonary embolism iyakwenzeka ngoko ukuba i-clot yegazi iphuma kwi-vein kwaye idlulele emzimbeni kumphunga. Oku kunokukhokelela ekufeni.
IMPENDULO - AKUNAKUNYE I-PANIC. NAKUBA UFANELE UQONDE UKUQALA:
I-FDA iye yaphanda ikhonkco ekhoyo phakathi kwe-drospirenone kunye nengozi yegazi. I-arhente iqhube isifundo sayo sokuxhaswa ngemali esibhekisele kwi-data esuka kwabasetyhini abangaphezu kwama-800,000. Ngo-Oktobha 2011, i-FDA ikhuphe iziphumo zolu pho nonongo kwaye ibonisa inkxalabo malunga nokunyuka kwe-1/2 kwenyuka kwimiba yegazi kwindoda yabasetyhini abasebenzisa iiprospirenone iipilisi.
Ngomcebisi we-Apreli 2012, i-FDA yazisa ukuba i-arhente yayigqibile ukuhlaziywa kwayo kwenkqubo yophando kunye ne-epidemiologic ekhoyo malunga ne-drospirenone kunye nengozi yegazi. Ngokusekelwe kulo mbononongo, i-FDA iqukumbele ukuba iipilisi zokulawulwa kokuzalwa kwe-drospirenone zingaxhunyaniswa nomngcipheko ophezulu wegazi kunye nokubiza iimfuno ezintsha zokubhaliweyo kulezi pilisi. Nangona kunjalo, i-arhente iphinde ibonise ukuba olu uphando aluzange lunikeze iziphumo ezingaguqukiyo okanye i-akhawunti yeziganeko ezibalulekileyo zezigulana ezinokuthi zenze igalelo kumngcipheko wegazi. Nangona i-FDA ibonise ukuba kunokubakho unxibelelwano phakathi kwe-drospirenone kunye negazi lomngcipheko wegazi, baphinde bavakalise ukuba i-arhente ayengacacanga ukuba le ngozi eyongeziweyo yecala legazi empeleni ngenxa ye-drospirenone kulezi pilisi zolawulo lokuzalwa.
Yintoni i-Drospirenone kunye negazi lokucima ingozi kuthetha kum?
Kule ngongoma, akukho mfuneko yokwesaba xa okwamanje usebenzisa ipilisi yokulawula ukuzalwa equkethe i-drospirenone. I-FDA icebisa ukuba:
- Akufanele uyeke ukuthatha ipilisi yakho ngaphandle kokuqala ukuthetha nodokotela wakho .
- Ukuba unenkxalabo okanye imibuzo, kufuneka uxoxe ngale nto kunye nogqirha wakho.
- Ukuba ucinga ngokutshintsha iindlela zokukhulelwa (okanye ufuna ukuqala ukusebenzisa ulawulo lokuzalwa ), kubalulekile ukuba uthethe ugqirha wakho malunga nobungozi begazi lakho ngaphambi kokugqiba indlela yolawulo lokuzalwa lokusebenzisa.
I-FDA ibuye ixelele oogqirha ukuba baqwalasele ingozi kunye neenzuzo zeepilisi zokulawula ukuzalwa kwezidakamizwa ze-drospirenone kunye nomngcipheko wesifazane wokuphuhlisa ama-blood clots ngaphambi kokucwangcisa la mapilisi.
Ukuba usebenzisa iipilisi zokulawula i-dropspirenone njenge-Yaz, Yasmin, Beyaz okanye iSaferal, kufuneka uqaphele oku kulandelayo:
- Ukuba uhlelwe ukuhlinzwa okukhulu, kufuneka uyeke ukusebenzisa iipilisi zakho zokulawula ukuzalwa kweeprospirenone okungenani ezine iveki ngaphambi kokuba usebenze kwaye ulinde iiveki ezimbini emva kokuqala ukuzisebenzisa kwakhona.
- Kuya kuba luncedo ukuba uyakwazi ukuqonda iimpawu zegazi . Ezi ziquka intlungu yesifuba, umlenze oqhubekayo okanye ingalo yesandla (kunye nokukhupha, ukufudumala nokubomvu) kunye / okanye ukuphefumula ngokukhawuleza. Ukuba ufumana ufumana nayiphi na le mpawu, kufuneka ukhawuleze ugqirha ugqirha wakho.
- Ukuba uvalelwe ekuphumleni kokulala okanye uphononongo okanye uza kuhamba ibanga elide (4 okanye ngaphezulu iiyure), unokuba negalelo eliphezulu legazi lomngcipheko.
- Ukuba utshaya, uneminyaka engaphezu kwama-35 ubudala kwaye usebenzisa nayiphi na inhlanganisela yokulawula iipilisi, umngcipheko wokuba ufumana iziganeko ezinzulu zentliziyo, njengama-clots egazi, ukwanda.
Ezinye Izizathu Zokuba Ufanele Uhlolisise Ngogqirha Wakho:
Ngenxa yokwanda kwenzuzo yengozi yegazi, kunokuba yinto elungileyo ukuba uhlolisise ngogqirha wakho ukuba udityaniswe kwipilisi yokuzala yokuzalwa ephethe i- ethinyl estradiol kunye ne-drospirenone yinto ekhethekileyo kuwe. Ngenxa yokuba i-drospirenone inokwandisa amazinga e-potassium okanye iphazamise imishanguzo ekwandisa i-potassium, ugqirha wakho kufuneka alandele amanqanaba akho e-serum potassium ngenyanga yokuqala yokusetyenziswa xa uphathwa ngayo naziphi na iziyobisi ezinxulumene nokugcinwa kwe-potassium. Ezi zi yobisi zingabandakanya:
- I-potassium yongezwa nge-ACE inhibitors (Vasotec, Capoten, Zestril nabanye)
- Aldosterone
- I-potassium-sparing diuretics (i-spironolactone nabanye)
- Heparin
- I-NSAID (ibuprofen [Motrin, Advil], naproxen [iAleve nabanye] xa kuthathwa ixesha elide kunye nosuku unyango lwe- arthritis okanye ezinye iingxaki)
- I-Angiotensin-II i-receptor antagonists (Avapro, Cozaar, Diovan nabanye)
Ukongeza, ukuba usebenzisa okwamanje i-Yaz, Yasmin, Beyaz okanye iSaferal kwaye unayo nayiphi na iimeko ezilandelayo, unokufuna ukuthetha nodokotela wakho ukuqinisekisa ukuba olu khetho lokukhusela lokukhusela olukhuselekileyo kuwe:
- Uxinzelelo oluphezulu lwegazi
- Imbali yamacango egazi kwimilenze yakho, emaphaphu okanye amehlo
- Imbali yesifo se-adrenal, isifo sesifo okanye isifo sesibindi
- Unesifo sikashukela ngeentso, iso, imbilini okanye umonakalo wezazi zegazi
- Ngaba unesifo senhliziyo, isifo okanye umlando weengxaki zentliziyo ye-valve okanye intliziyo yengqungquthela engafanelekiyo eyenza ukuba iimbumba zegazi zenzeke entliziyweni
I-DROSPIRENONE NENKQUBO YOMSEBENZI WEMIGAQO - I-BOTTOM LINE:
Ngokubanzi, ukuba ngabafazi aba-10 000 (abangakhulelweyo kwaye bangasebenzisi izilwanyana zokulawula ukuzalwa) balandelwa kunyaka owodwa, phakathi ko-1 no-5 kulaba bafazi baya kuphuhlisa i-clot yegazi. Nangona unokuba ngumngcipheko omkhulu kumacandelo egazi xa uthatha ipilisi yokulawula i-dropspirenone, ndingathanda ukukukhumbuza kwakhona ukuba ukusebenzisa nayiphi na intsebenziswano yokukhulelwa komlomo ingakufaka ingozi ekuphuhliseni ama-blood clots.
Umngcipheko we-thromboembolism (i-thongsis ye-vein thrombosis kunye / okanye i-pulmonary embolism) kubasetyhini abasebenzisa nayiphi na inxalenye yentsebenziswano yokuqhawula i-rap ayinqabile kwaye iqikelelwe ukuba yi-3 ukuya ku-9 kwabasetyhini abayi-10,000 (ngonyaka). Olu mngcipheko luphezulu kunyaka wokuqala wokusetyenziswa (ingakumbi kwiinyanga ezi-6 zokuqala). Umngcipheko omkhulu we-thromboembolism ubonakala ngathi emva kokuba uqale uqale ukuthatha ipilisi yentsebenziswano okanye uphinde uqalise iphilisi efanayo okanye uphawu oluthile (ukuba lube ngaphezu kweeveki ezine ukususela ekugqibeleni usebenzisa ipilisi).
Wena kunye nogqirha wakho kufuneka uqikelele ingozi yamacwecwe egazi (kunye nezinye iziphumo ezichaphazelekayo ) kunye neenzuzo zepilisi (zombini ukukhusela ukukhulelwa kunye neengxaki zokungakhulelwa ).
Yonke into ekuthethwa ngayo, kubalulekile ukuba ugcine umngcipheko wegazi kwi-perspective: ingozi epheleleyo yokuphuhlisa i-clot yegazi iphantsi kakhulu. Nangona unomngcipheko wegazi ophezulu xa usebenzisa ipilisi (ngokubhekiselele kokungasebenzisi i-hormonal contraception ), le mngcipheko usaphantsi kunomngcipheko wegazi wokuba ukhulelwe okanye emva kokuzala:
- Igalelo lomngcipheko wegazi kwabasetyhini beminyaka yobudala abangayisebenzisi ipilisi (ama-1-5 amacala angama-10,000 abafazi)
- Igazi lomngcipheko wegazi ngelixa usebenzisa ukusebenzisa iipilisi zokulawula ukuzalwa (ama-5-7 amatyala angama-10,000 abafazi)
- Igazi lomngcipheko wegazi ngelixa uthabatha iipilisi nge drospirenone (amacala angama-9-12 ngamabhinqa angama-10,000)
- Igazi le-clot lengozini ngelixa likhulelwe (landa ukuya kuma-29 kwabesetyhini aba-10 000)
- Igalelo lomngcipheko wegazi ngelixa emva kokubeleka / iiveki ezili-12 emva kokubeleka (kubikwe njengama-40-65 kwabesetyhini ngabasetyhini abayi-10 000).
Imithombo:
Ikholeji yase-American College of Obstetricians kunye neGynecologists. "Ingozi ye-thromboembolism phakathi kwabasebenzisi be-drospirenone equkethe iipilisi zokukhulelwa komlomo." I-Opinion yekomiti ayi- 540. I- Obstet Gynecol 2012 ( eqinisekisiwe ngo-2014); 120: 1239-42. Kufumaneka ngokubhalisa kwangasese.
FDA. [4-10-2012] "Ukuhlaziywa kwemibuzo yangaphandle kunye nezimpendulo - Ukuhlaziywa okuqhubekayo kokuphepha kwamapilisi okuzalwa okuqukethe i-drospirenone kunye nokunyuka kwengozi yegazi." Ufikelele ngomhla we-1/27/15.
FDA. [10-27-2011] "I-FDA yoNxibelelwano loKhuseleko lweMithi: Ulwaziso oluhlaziyiweyo malunga novavanyo lwe-FDA oluxhaswa ngemali kwingcipheko yamacandelo egazi kwabasetyhini abaphethe iipilisi zokuzalwa eziphethe i-drospirenone." Ufikelele ngomhla we-1/27/15.
James AH. "I-thrombosis enxulumene nokukhulelwa." Hematol 2009; 277-85. Kufumaneka ngokubhalisa kwangasese.
Health PubMed. "I-media hype blood clot mngcipheko wokulawula iipilisi zokuzalwa." ILayibrari yesizwe ye-US yeMicrothelo / amaZiko eZiko lezeMpilo. 03 Febhuwari 2014. Kufumaneka 1/27/14.