I-Tylenol, ebizwa ngokuba yi- acetaminophen , isisityebi esithandwa kakhulu nesisebenzayo esithathwe ekunciphiseni ubuhlungu nokunciphisa umkhuhlane. Ngenxa yokuba yayaziwa kakhulu (ifunyenwe ukususela ngee-1950s) kwaye ixhaphake kakhulu (ihlanganiswe kakhulu namanye amayeza), ngamanye amaxesha isetyenziswa ngokungakhathaliyo leyo ingakhokelela kwimonakalo yesibindi .
Ngaba iTylenol Ikhuselekile?
I-Tylenol ikhuselekile kakhulu xa isetyenziswe njengenconywayo.
Abantu abaninzi abane- hepatitis engapheliyo kunye nezinye iintlobo zezifo zesibindi (abangasayi kuvutha kotywala) bangathatha ngokukhuselekileyo amanani aphakanyisiweyo aTylenol; Nangona kunjalo, kufuneka uqwalasele ngogqirha wakho ngaphambi kokuba uthathe nawaphi na amayeza ukuba unesifo sesibindi.
Kubantu abane- cirrhosis eziphambili (i-cirrhosis echithwayo), mhlawumbi iTylenol ayinakusetyenziswa ngenxa yomonakalo omkhulu wesibindi. Ukuba unesifo esiqatha sesibindi, xela ugqirha malunga neendlela ezifanelekileyo zokufumana unyango okanye iintlungu.
Kutheni Isibindi Sithinteka nguTylenol?
I-Tylenol ixakeka ngokukhawuleza egazini ngephepha lesisu. Kanye egazini, liqala ukukhulula intlungu ngokunyusa umzi womzimba wakho kwiintlungu kwaye kunciphisa umkhuhlane ngokukunceda ukulahla ukushisa okukhulu. Ekugqibeleni, igazi lihlutha kwisibindi apho ininzi yesicatshulwa idibeneyo (idilizwe phantsi) kunye neyunxenye zayo zixutywe emcinini.
Ingozi Yenzani evela eTylenol Iyenzeka Njani?
Isibindi sichitha ininzi yesilwanyana kwiindawo ezikhuselekileyo ezingasuswa emzimbeni kumchamo. Nangona kunjalo, inani elincinci leTylenol kulindeleke ukuba libe ne-metaboli engumngcipheko ngemveliso ebizwa nge-NAPQI (emele iN-acetyl-p-benzoquinoneimine).
Xa iTylenol ithathwa kwii-doses ezicetyiswayo, umzimba wakho unokukhawuleza ukususa lo mveliso onobuthi kwi-urine. Nangona kunjalo, xa isibindi sifanele siphumeze ngokukhawuleza amanqanaba angaphezulu kweTylenol, i-NAPQI eninzi yingozi kwaye iqala ukulimaza iiseli eziphambili zesibindi (i-hepatocytes).
Indlela Yokuphepha Ngokuthatha iTylenol
Ukuba isetyenziswe ngogqirha odityanisiweyo, ukuthatha iTylenol kukhuselekile, nangona ininzi yabantu abanezifo zesibindi abangaphuzanga utywala. Umonakalo wesibindi ukusuka eTylenol unokuxhomekeka kwizinto eziliqela. Ezinye zazo zi:
- Isixa seTylenol uthatha (ukuba uthabatha ngaphezu kwexabiso eliphakanyisiweyo)
- Ubungakanani botywala ophulayo (utywala lunokwandisa umveliso we-NAPQI enetyhefu)
- Ukuba uthatha amanye amayeza kunye neTylenol (ezinye iziyobisi, kuquka ukuxhaswa kwemfuyo, zingasebenzisana kakuhle neTylenol kwaye zandisa ingozi yomonakalo wesibindi)
- Umgangatho wakho wesondlo (nokuba uzila ukudla okanye ukuba unesondlo esingenasondlo kunokunyusa umngcipheko wesibindi)
Ukugqithiswa kweTylenol kuthathwa njani?
Ukugqithisa kweTylenol kunokuba kungenjongo okanye ngengozi. Ngenye yezona zityhefu eziqhelekileyo ezenzeka emhlabeni jikelele. Ukuba ingakhange iphathwe ngokukhawuleza, iTylenol ukudlula ngaphezulu ingaba yingozi.
Abantu abadlulayo kwiTylenol banokufumana iimpawu ezilandelayo:
- isifo sohudo
- zixhala
- ukucaphuka
- jaundice
- isicaphulelo
- ukuthuka
- ukuhlanza
- coma
- ukulahleka kwesidlo
Ingqalelo, kungathatha iiyure ezili-12 emva kokungena kweempawu zeTylenol ukudlula ngaphezulu.
I-Tylenol ukudlula iimeko ezingxamisekileyo. Ngethamsanqa, i-antidote yeTylenol igqithiseleyo kwaye ibizwa ngokuba yi-N-acetylcysteine. Eli daba liyasebenza kakhulu xa linikwe kwiiyure eziyi-8 zeTylenol ukudlula, kwaye inokuthintela ukuhluleka kwesibindi .
Imithombo
Utshisa uMJ, uFriedman SL, uLarson AM. I-Acetaminophen Inetyhefu kuBantu abadala: i-Pathophysiology, i-Presentation, kunye ne-Diagnosis. Ku: U-UpToDate, iBasow, iDS (Ed), UpToDate, i-Waltham, MA, 2009.
Iwebhusayithi yeTylenol yeNkampani. I-Tylenol Imibuzo Ebuzwa Ngokuphindaphindiweyo.
I-Desk Reference Desk (PDR). Umhla wesi-63. UMontvale, NJ: Thomson PDR; 2009: 1915-16.