Iimpembelelo ezithile zeeNkcazo kufuneka zixelwe kwiGqirha lakho elifanelekileyo
Yintoni i-Imuran (Azathioprin)?
I-Imuran (azathioprine) luhlobo lwe-immunosuppressive drug antimetabolite. I-Imuran inokumiselwa ukunyanga iimeko ezifana nesifo sesibindi sokugula (IBD) okanye i-rheumatoid arthritis. Ingasetyenziselwa kwakhona kwizigulane eziye zatshintshiswa ilungu, ukwenzela ukukhusela umzimba ukuba unqabe ilungu. Eli cheza likhupha isistim somzimba.
Kwiimeko ezininzi, i-Imuran isetyenziselwa ukuphatha i-IBD emva kwezinye iziyobisi ezingasebenzi. Ingasetyenziswa kwakhona ngexesha elifanayo njenge-steroids.
Amachiza anokuchaphazela isistim somzimba anganyusa umngcipheko wokuphuhliswa kwesifo, kwaye kufuneka kuqhotyoshelwe ukuthintela ekukhuselaneni nezifo. Abantu abathatha i-Imuran akufanele bafumane nayiphi na igciwane lokuphila. Kwakhona kunokufuneka ukuba ugweme abantu abagulayo kunye naluphina uphawu losulelo kufuneka luxoxwe nodokotela ngokukhawuleza.
Isilumkiso seBlack Black
Iipilisi ze-Imuran ziqulethe ibhokisi ebumnyama isilumkiso esichaphazelekayo ekuphuhliseni uhlobo oluthile lomhlaza. Oku kudibene ngokukodwa kubantu abathatha iziyobisi kunye ne-IBD. Umngcipheko wokuba nomhlaza kufuneka ulinganiswe nomngcipheko wokungaphathi i-IBD nale nkunkuma.
Ubungozi be-Cancer kubantu abane-IBD basesihloko esiqhubekayo sokuxubusha kunye nokufundisisa, ngoko kubalulekile ukuthatha indlela yokuqonda xa uhlola ingozi.
Ezinye izifundo zibonise umngcipheko, kodwa ezinye azikho. Qinisekisa ukuxoxa ngale mpembelelo echaphazelekayo kunye namagqirha akho ukuze ukwazi ukuqonda ingozi yakho.
Ukunyanzelwa kwe-immunosuppression nge-IMURAN, i-purin antimetabolite iphakamisa umngcipheko wokuhlaselwa kwabantu. Iingxelo zentlungu zibandakanya i-post-transplant lymphoma kunye ne-hepatosplenic T-cell lymphoma (i-HSTCL) kwizigulane ezinezifo zesifo. Oogqirha abasebenzisa eli chiza kufuneka baqhelane kakhulu nale mngcipheko kunye nekhono lomtamente kumadoda kunye nabasetyhini kunye neentlobo zetyhefu. Oogqirha kufuneka baxelele izigulane zengozi yokugula kunye ne-IMURAN.
Iimpembelelo eziqhelekileyo ze-Imuran
Hlola kunye nogqirha wakho ukuba ngaba ziphi iziphumo ezilandelayo ziqhubeka okanye zixhalabisa:
- ukulahleka kwesidlo
- isicupunu okanye ukuhlanza
Imiphumo engaphantsi yama-Imuran
Hlola kunye nogqirha wakho ukuba ngaba ziphi iziphumo ezilandelayo ziqhubeka okanye zixhalabisa:
- Ukugqithisa isikhumba
Njalo Ukwazisa ugqirha
Okuqhelekileyo
- Ukhuhlane, ukuphazamiseka
- ifivil okanye i-chills
- intlungu engaphantsi okanye intlungu
- ukuvuthwa okunzima okanye okunzima
- ukukhathala okungavamile, ubuthathaka
Ngaphantsi
- Amnyama, iitars
- igazi kumchamo okanye izitishi
- ubhekise amabala obomvu esikhumbeni
- ukuphaphaza okungavamile okanye ukutyumla
Ngaphantsi okanye ngokuqhelekileyo
- Ukunyaniseka kwentliziyo
- umkhuhlane (ngokukhawuleza)
- intlungu okanye intlungu
- isicupunu, ukuhlanza, kunye nesifo sohudo (esinzima)
- ubomvu okanye i-blisters kwesikhumba
- ukuqhawukelwa ngumphefumlo
- izilonda emlonyeni, emilonyeni
- intlungu yesisu
- ukuvuvukala kweenyawo okanye imilenze ephantsi
- uvakalelo okanye ukugula (ngokukhawuleza)
Amanye amanqaku:
Ugqirha wakho uya kujonga nayiphi na ingxaki yesibindi eli liyeza.
Ngenxa yendlela le mayeza enza ngayo emzimbeni, kukho ithuba lokuba kungabangela ezinye iziphumo ezingafunekiyo ezingaze zenzeke de iinyanga okanye iminyaka emva kokuba iyeza lisebenzisa. Ezi ziphumo zilibaziseko zingabandakanya iintlobo ezithile zomhlaza, ezifana ne-leukemia, i-lymphoma, okanye umdlavuza wesikhumba. Umngcipheko womhlaza ungaphantsi kubantu abathabatha i-azathioprine kwi-arthritis, kwaye kufuneka uxoxe ngeziphumo ezinokuthi ugqirha wakho.
Emva kokumisa eli liyeza, kunokusenokuba nemiphumo emibi. Ngeli xesha xelele ugqirha wakho ngokukhawuleza xa ubona naliphi na oku kulandelayo:
- amnyama, iitars
- igazi kumchamo
- ukukhwehlela okanye ukuphazamiseka
- ifivil okanye i-chills
- intlungu engaphantsi okanye intlungu
- ukuvuthwa okunzima okanye okunzima
- ubhekise amabala obomvu esikhumbeni
- ukuphaphaza okungavamile okanye ukutyumla
Ezinye iziphumo ezichazwe ngasentla zingenzeka kwezinye izigulane. Ukuba uqaphela nayiphi na imiphumo, khangela kogqirha wakho. Olu lwazi lubhekiselwe nje kuphela njengesikhokelo-soloko udibana nogqirha okanye ophmistri ngolwazi olupheleleyo malunga neyeza zokunyanga.
Umthombo:
Prometheus Laboratories Inc. " Imuran (azathioprine) Ukuchaza ulwazi ." FDA.gov. Feb 2014..
I-Armstrong RG, i-West J, iKhadi le-TR. "Ingozi yomdlavuza kwisifo sofuba esiphefumulayo esaphathwa nge-azathioprin: i-UK-based study-control control study." Am J Gastroenterol . 2010 Julayi; 105 (7): 1604-1609.