Yintoni i-tubular carcinoma yebele? Uhluke njani kwezinye iintlobo zesifo somhlaza webele kwaye le nto ihluke njani kumabele e-tubular? Makhe sijonge iimpawu, ukuxilongwa, kunye neendlela zokonyango, kunye nokuchazwa kwesi sifo esingavamile somhlaza wesifuba.
I-Tubular Carcinoma yeBreast Defined
I-carbulaoma ye-Tubular yinto engaqhelekanga ye- ductal carcinoma yebele.
Kuthatha igama layo kumbonakalo walo omncinci, apho iiseli zomhlaza zifana nezicathulo ezincinci.
I-carbulaum ye-tubular iyaba yincinci, i- estrogen-receptor enhle , i- HER2 / neu kancinci. Kwezinye iimeko, iiseliti zomhlaza ezixubileyo zixutywe kunye neeseli zomhlaza zesifo se-ductal okanye i-lobular, zinika ukuxilongwa kwe-tumor.
I-tubular carcinomas ziye zaba malunga neepesenti ezingama-2 zazo zonke i-diagnostic zebele zesifuba, kodwa le namba iyanda, mhlawumbi eyesiqhelo kwindlela yokuhlola i-mammogram. Abantu abahlakulela i-carbulaoma ye-tubular baqhelekile kwiminyaka engama-50 okanye ngaphezulu.
I-tubular carcinoma yaziwa nangokuthi ngumhlaza webele we-tubular, i-TC, kunye ne-tubulolobular carcinoma (TLC), xa ixutywe ne-lobular carcinoma.
Ukwahlukana Phakathi kweTubular Carcinoma kunye neeBabele zaseTubular
Izibilini zamathambo, okanye amabele asobuhlungu, isifuba esiswini sokubeleka apho amabele aphuhlisi khona izicubu ezinokuthoba njengesibeleko esivuthiweyo. Izibilini zamathumbu zinokuba nezikhulu ezinkulu, zincinci kakhulu eludongeni lwesifuba, kwaye zikhule ngendlela edibeneyo.
Utyando lwePlastiki lunokwenziwa ukubuyisela kwakhona amabele e-tubular ibe yinto eqhelekileyo. Ukuba nesifuba se-tubular yimeko ehlukile kunokuba ne-carbulaoma ye-tubular.
Izimpawu kunye neMpawu
Akunakukwazi ukuva utywala nge-tubular carcinoma kwaye ezi ngqayi zihlala zibonisa kuqala kwimimmogram . Ukuba ixutywe kunye neeseli zamathambo ezingenayo kwaye sele iqulunqe isona esiphezulu, unokukwazi ukuziva udoti lwe-ductal.
Xa iiseli zomhlaza zihlanganiswe nomhlaza wesibeletho se-lobular (i-tubulolobar), iimpawu zakho zinokufana ne- lobular carcinoma engapheliyo , njengendawo ekhuniweyo kwiimviwo kodwa ngaphandle kwento ecacileyo.
Ukuxilongwa
I-carbulaum ye-tubular isoloko encinci kodwa ingabonakalisa kwi-mammogram njengobunzima obungasifanelanga kunye ne-spiky, okanye inkcazo yeenkwenkwezi. Kwi- breast ultrasound , i-carbulaoma ye-tubular ingabonakalisa ubunzima obunomxholo obanzi kwaye unokuba nokubalwa kwamanani .
I-centre ye-carbulaoma ye-tubular iya kuba yimbi kakhulu kuneendawo zangaphandle zobunzima. Kuya kufuneka ukuba i- biopsy ifumane isampuli yeesisisulu ukuze i-pathologist ingenza uvavanyo oluncinci, oluza kubonelela ngokucacileyo.
Unyango
t, nangona ezi zinokuthi zihluke kwezinye iisifo zomhlaza njengokuba ezi zicubu zingenako ukusabalalisa. Izinketho ziquka:
Ugqirha: Okwenziwe i-mastectomy okanye i- lumpectomy ukususa ezi zicubu. Ekubeni iimvumi zihlala zincinci, i-lumpectomy ingaba yinto efanelekileyo. I-nodeinel node biopsy ivame ukwenza, kuba iimbumba ezincinci (umzekelo, 1 cm) zinokubandakanyeka kwe-lymph node.
Uphulo lwe-radiation: Njengoko i-lumpectomy idlalwa yila ma-tumors, unyango lwe-radiation lisetyenziswe emva kokuhlinzwa ukuze uphathe iisifuba eziseleyo.
Unyango lwama-Hormonal: Njengoko i-carcinomia ye-tubular isoloko i-estrogen-receptor efanelekileyo, unyango lwe-hormonal lungasebenza kakhulu ekunciphiseni umngcipheko wokuphindaphinda. Kubafazi be-premenopausal, i- tamoxifen isetyenziswa rhoqo. Kubafazi besimo se-postmenopausal, okanye abafazi be-premenopausal abaye banqunyulwa ama-ovari okanye unyango lwe-ovarian, i- aromatase inhibitors zivame ukucetyiswa. Unyango olunjalo ngala mayeza kanconywa ukuba i-tumor ikhulu kune-1 cm kunye / okanye ukuba i-lymph nodes zilungile.
I-Chemotherapy: Njengoko ezi zicubu zingenakwenzeka ukuba zisasaze kwii-lymph node, kwaye ngoko ke kwezinye iindawo zomzimba, akunakwenzeka ukuba i-chemotherapy ene-adjuvant iyakufuneka kulezi zicubu.
I-Chemotherapy, nangona kunjalo, ngokuqhelekileyo iyanconywa ukuba ngaphezu kweyodwa i-lymph node ifanelekile.
Ukulandelwa Emva kokunyanga
Ukulandelelana ngokunyameko emva kokuba unyango luyadingeka njengawo nawuphi na uhlobo lomhlaza wesibele. Akuqhelekanga kubafazi ababenomdlavuza we-tubular ukuba bahlakulele umhlaza kwezinye ibele, kwaye ngoko kuhlolwa kunye ne-mammogram kunye ne-MRI kubaluleke kakhulu.
Ubukhulu besisu kunye nePrognosis
Iidumbu ze-tubular zihlala zincinci (1-2 cm ububanzi) kwaye aziqhelekanga zisasaze ngaphaya kweendawo zangasese zesilonda. Kunokwenzeka, kodwa engavamile, ukuba i-carbulaoma ye-tubular ihambe kwii-lymph nodes zakho - kwaye i-lymph nodes engathintekiyo ithetha ithuba elincinane le-metastasis. Ithuba lakho lokuphulukana nokuphila emva kokuba unyango lwe-carbulaoma ye-tubular luhle kakhulu. Ngokubanzi, ukugxekwa kwe-carcinoma ye-tubular kungcono kunokuba i-ductal carcinoma okanye i-lobular carcinoma.
ILizwi
I-tubular carcinoma yesifuba ngumhlaza odla wancinci kwaye ngokuqhelekileyo unesifo esihle. Oko kwathiwa, nayiphi na umhlaza kunoma yiphina isigaba eyoyikisayo. Kubalulekile ukufikelela kubahlobo bakho kunye nosapho. Cinga ukujoyina umntu-ngaphakathi okanye iqela lokuxhasa inthanethi. Funda ngokusemandleni akho ngesifo sakho. Ngama-tumors aqhelekanga, kunokuba luncedo ukufumana umbono wesibini kwenye yeziko elikhulu lomhlaza ongase ube nama-oncologists aphethwe ngabantu abaningana nale ngqumbo. Ezi zicubu zihlala zincinci kodwa zithatha ukusabalala kwii-lymph nodes kwisigaba esincinane kunezinye iintlobo zomhlaza. Ngethamsanqa, uninzi lwala ma-tumor is receptor positive receptor, kwaye i-hormone therapy ingasebenza ekunciphiseni umngcipheko wokuphindaphinda.
> Imithombo:
> Fritz, P., Bendrat, K., Sonnenberg, M. et al. I-Cancer Breast Cancer: I-Retrospective Study. Uphando lweMveli . 2014. 34: 73647-3656.
> Min, Y., Bai, S., Lee, H. et al. I-Tubular Carcinoma ye Breast: Izixhobo zeClinikiopathologic kunye neSiphumo soPhuculo ngokuchazwe neDuctal Carcinoma In Situation. Umbhalo weCanscer Breast . 2013. 16 (4): 404-409.