I-antigen eneprostate (PSA) yinto eveliswa ngama-prostate cells (amacandelo amancinci asebenzayo aseprotate). I-PSA ijikeleza ngegazi. Ngexa egazini, i-PSA inokuqhotyoshelwe kwiiprotheni ezikhoyo egazini okanye zingenakunyaniswa ("mahhala"). Kuyinto eqhelekileyo ukuba i-PSA idibene kunye ne-PSA kwaye ayikho na yale fomu ye-PSA ithathwa njengesiqhelo.
I-"Pesenti-free" i-PSA ibalwa ngokuhlula inani le "PSA mahhala" yi- PSA iyonke.
Izifundo ziye zafumanisa ukuba, ngokuqhelekileyo, amadoda anomhlaza wesibeletho anamazinga aphantsi e-PSA ekhululekile xa kuthelekiswa namadoda ngaphandle komhlaza wesibeletho.
I-PSA engaqhelekanga kunye ne-PSA
Ngokuqhelekileyo, amadoda anepesenti ye-PSA engenamaphesenti angaphezu kweepesenti ezingama-25. Phakathi kweepesenti ezili-10 kunye neepesenti ezingama-25 kuthathwa njengoluhlu oluphakathi kwaye ngaphantsi kweepesenti ezili-10 kuthathwa njengento ephantsi.
Nangona kunjalo, i-PSA engenamaphesenti aphantsi, kunye ne-PSA yezinga eliphezulu (inombolo echaziweyo enikwe yona inombolo yakho ye-PSA), akuthethi ukuba unomdlavuza wesibeletho . I- biopsy kuphela iyakwazi ukuxilonga ngokucacileyo umdlavuza wesisu .
Ngaba i-PSA yam Ipesenti-ntliziyo ibhekisela nantoni na into?
Iimeko eziqhelekileyo apho i-PSA engekho ipesenti isetyenziselwa ukwenza isigqibo malunga nendlela yokuvavanya okanye ukunyanga umdlavuza we-prostate yilapho iqondo lePSA elipheleleyo liphakathi kwinqanaba eliphakathi.
Kule meko, ugqirha unokucebisa umntu ophethe i-PSA engenamaphesenti aphantsi (kwaye ke umngcipheko ophezulu wesifo somhlaza) kwaye ucebisa ngokubhekiselele kwi-biopsy kwindoda ene-PSA ephezulu-free (ngaphezu kwe-25 ipesenti).
Umxholo omtsha
Kwixesha elidlulileyo, oogqirha babethembele ngokuthe ngqo kwizinga le-PSA elipheleleyo ukugqiba ukuba ngaba unokuba nomdlavuza wesibeletho.
Ngokukhawuleza ke, kwacaca ukuba ukusebenzisa i-PSA nqanaba liphela ngeendlela ezithile ezibalulekileyo.
Ngomnye, amadoda athile aphantsi okanye aphantsi aphantsi kwe-PSA amanqanaba afumaneke ukuba nomhlaza wesibeletho. Okwesibini, amadoda amaninzi anamazinga aphezulu e- PSA ayinayo umdlavuza wesibeletho. Kunoko, banesimo esincinci kunobungozi njenge- benign prostatic hyperplasia (BPH) .
Ngokwenene, i-PSA nqanaba lihlala lichaze ibali lonke. Oogqirha sele sele beqala ukusebenzisa ezinye iindlela ze- PSA ezifana noxinzelelo lwe - PSA kunye ne-PSA engenamaphesenti e-PSA ukwenza izigqibo ezingcono malunga nomngcipheko womdlavuza wesibeletho.
Imithombo
Saraiya M, Kottiri BJ, Leadbetter S., et al. Ixabiso kunye neepesenti zama-prostate- ahlukeneyo amanqanaba e- antigen phakathi kwamadoda ase-US, 2001-2002.
Uemura H, Nakamura M, Hasumi H., et al. Ukuphumelela kwepesenti e-prostate-specific antigen njengendlela yokuqaphela umdlavuza weprotate ngokuphindaphinda. Int J Urol. 2004 Julayi; 11 (7): 494-500.