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Utshintsho lwe-Fecal?Ukufakelwa kwe-fecal, eyaziwa nangokuthi yi- bacteriotherapy ye-fecal , yinkqubo yokubuyisela iibhaktheriya eziqhelekileyo kwi-digestive tract nge-infusion ye-feces (stool) evela kumnikeli. Nangona oku kufana nengqiqo engaqhelekanga, kubalulekile ukukhumbula ukuba imizimba yethu ifuna iibhaktheriya ukuba zime ukutya. Ibhaktheriya inceda kwakhona ukugcina ukunyakaza okuqhelekileyo kokutya kunye nesigxina ngokusebenzisa isisu. Xa ibhaktheriya kwindlela yokugaya ichithekile, kunokuba nzima kakhulu ukubuyela.
I-Bacterial Fecal - Flora ejwayelekile
Umntu oqhelekileyo unamakhulu ezindidi zeebhaktheriya kwindlela yokugaya. Ngelixa kunokwenzeka ukuba uphile ngaphandle kwezi bhaktheriya, ezibizwa ngokuba yi-flora eziqhelekileyo okanye izityalo zokutya, zixhamla kakhulu umzimba. Ezi bhaktheriya "ezilungileyo" zinceda ukunqanda ukugqithisa kweebhaktheriya ezimbi, zinokuphucula umzimba wamasosha, kwaye zidlala indima ekwehleni ezinye iindidi ze-carbohydrate engapheliyo.
Xa sizalwa, sinemibhaktheriya kwindlela yethu esiyifumanayo kumama, njengolu hlobo "lwenkcubeko yokuqala." Ukuba ukutshatyalaliswa kweebhaktheriya kunzima ngokwaneleyo, akukho nto inokwanela ukubuyela kumanqanaba aqhelekileyo ngaphandle kokuthatha i-flora yesiqhelo njengesiqalo sesibini sokuqala.
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Kutheni iifama zitshaliswa?Iifesi zitshintshelwe ukuba zitshintshe iibhaktheriya ezilahlekileyo okanye zonakaliswe yisifo okanye unyango. Kwiindlela eziqhelekileyo zokugaya ukutya, kukho iintlobo zeentlobo ezahlukeneyo zebhaktheriya. Ezi bhaktheriya, ezibizwa ngokuba yi-flora eziqhelekileyo, ziyimfuneko yokugonywa ngokufanelekileyo kwaye zidlala indima ekuthinteleleni ukunyuka kwemizimba kunye nokuphucula imisebenzi yomzimba.
Kwiindlela eziqhelekileyo zokugaya inyama, amakhulu amabhaktheriya ahlukeneyo awenza izityalo eziqhelekileyo azisebenzela ukugcina ibhalansi, ukugcina nayiphi na ibhaktheriya enye kwi-overgrowing. Ibhalansi yinto enesicatshulwa, kwaye xa unyango luphazamisa, ukugqithisa kunokwenzeka. Isiphumo sinokuphazamisa kwinkqubo yokutya. Kwiimeko ezininzi, inkqubo yokugaya inyama ibuyisela emva kwayo, ibuyisela i-flora eqhelekileyo. Kwabanye, nangona kunjalo, iziphumo ezigqithisileyo ziziphumo eziphindaphindiweyo zoxinzelelo lwesisu kunye neentyatyambo ezincinane eziqhelekileyo ukuze ziphumelele. Kwabo, i-bacteriotherapy ye-fec yindlela yokonyango ebalulekileyo.
Amagqabi angatshintshwa njengonyango lwe- clostridium difficile colitis, eyaziwa ngokuba yi "C. diff". C. ngokuqhelekileyo iziphumo ezivela kwikhosi ye-antibiotiki ezibulala amagciwane angcono kwinkqubo yokubulala ibhaktheriya embi. Kwizigulane ezigula kakhulu, iCC diff ingakhokelela ekuqhutyweni okongeziweyo okanye ukufumana ixesha elide. Ukuba isigulane sakho esiphezulu sivumelanisa iC C., akufuneki kubekho isidingo se-bacteriotherapy ye-fecal, njengoko le nyango isetyenziswe kuphela kulabo abaneC. Kungenxa yezi gulane ezifanele ukufumana ubomi ezinokuphuculiswa ngokuphawulekayo kunye nokufakelwa kwefecal.
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Ngokukrakra? I-Fecal Bacteriotherapy Transplant Ingaba Uncedo Lokwenene?I-squeamishness ingaba yintloko ebangela ukuba abantu abangenayo inqubo ye-bacteriotherapy ye-fecal. Xa bejamelene neengxaki zentlungu eziphindaphindiweyo, nangona kunjalo, ingcamango yokwamkela ukuxhamla komfaki wanikela unokunyamezela kwizigulane ezininzi. Uninzi lweemeko eziyimfuneko yokutshintshwa kwefecal kubangela i-diarrhea eninzi, ephindaphindiweyo kunye eqhubekayo.
Ekuqaleni, ingcamango yokufakelwa kwefecal ibonakala ngathi ihlaya - nangona, ngokutsho kwesinye isifundo, i-bacteriotherapy ye-fec ine-91%. Kwizigulane ezithobela ngokuphindaphindiweyo iC C. difficile, kunye neempawu ezigqithiseleyo ezinxulumene nayo, "ubunzima" bunokuba yiyona nto.
Ukufakelwa kwe-Fecal kwamkelwa njengonyango lweenkqubo ezininzi zezifo zamathumbu. Nangona kunjalo, xa zisetyenziselwa ukunyanga i-ulcerative colitis kunye nezifo zesibindi sokuvuvukala , ukuguqulwa kwe-fecal kuthathwa njengonyango lovavanyo.
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Utshintsho lwezityalo luyenziwa njani?Isampuli yefecal ifumaneka kumnikeli ngaphakathi kweeyure ezintandathu kwenkqubo yokufakelwa. Ihlolwe kwaye ivivinywe ngama-parasites emathunjini kunye nezinye iimpawu zokugula ezinokulawula umniki-mali. Ukuba isampuli ifanelekile, ilungiselelwe ukutsalwa, ngokuqhelekileyo ngokuxuba ngamanzi angenayo kunye nokucoca ngefayili yefowuni ngokuphindaphindiweyo ukususa iziqulatho.
Le sampuli ingeniswa kummkeli ngenye yeendlela ezimbini, nge- enema okanye nge- tube yokutya .
Ukuba i-enema isetyenzisiwe, isampuli se-stool ifakwe kwisikhwama se-enema okanye ibhotile, kwaye ingeniswe kwi-rectum apho ibanjwa khona ixesha elide. Oku kwenziwa ngokuphindaphindiweyo kwikhosi engekho ngaphantsi kweentsuku ezi-5 ukuya kwi-10, ngokuzenzekelayo ukuvelisa iiflethi eziqhelekileyo ukuya kumathambo.
Enye indlela isebenzisa ityhubhu yokutya ukuze ifake isampula esezantsi ngqo emathunjini. Le bhubhu isetyenziselwa ukondla izigulane ezingakwazi ukunyamezela iintlobo zokutya okanye ukuthambisa i-tube. Ingeniswa kwimpumlo ize iphinde isisu, kwaye iyaqhubeka isondela kude ibe yintliziyo. Isampuli eselungiselwe ukutshintshwa kwandelwa ngokufakwe kwi-tube, evumela ukuba ibekwe ngqo emathunjini.
Kwezinye iimeko, i-enema kunye neendlela zokusondeza iifayili zingasetyenziselwa ukubuyisela kwakhona izityalo eziqhelekileyo kwi-digestive tract.
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Iifama zokuThuthukiswa: Ukubuyiselwa kwe-Autologous of Gastrointestinal Flora (ARGF)Ukubuyiselwa kwemvelo kwezityalo zesisu, okanye i-ARGF, isicwangciso esitsha esafundiswa ngoku. Kule nkqubo, izigulane ezisengozini yokutshatyalaliswa kweentyatyambo eziqhelekileyo zamathumbu zinikeza isampuli kwisitulo sabo. Isampuli igcinwa, kwaye ukuba kuyimfuneko, ihlongozwa kwaye ifakwe i-frozen-dry. Isampuli ifakwe kwi-capsule kwaye yatshitshisiwe, enjenge-ibuprofen okanye nayiphi imithi, ukuze ihambe emathunjini ngaphambi kokuba ichithe. Le ndlela, njenge-enema kunye neendlela zokusondeza ityhubhu, ibeka isampula eqhelekileyo yeflethi ngqo kwi-intestine apho iyakwenza ikholoni.
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Ngubani Ongabakho Umxhasi We-Fecal Transplantation?Ngokuqhelekileyo, iqabane elifanelekileyo okanye isihlobo sithathwa njengomviwa ofanelekileyo wokunikela ngemali. Akukho mfuneko yokuba umnikeli abe isihlobo; nawuphi na umntu ofanelekileyo unokuzivolontiya ukunikela. Imbali yonyango yomniki-mali iya kuhlolwa, kunye nemeko yabo yangoku yempilo. Umnikeli kufuneka abe namahhala wezifo ezithathelwanayo, njenge-hepatitis A, B kunye ne-HIV. Bamele bakhululwe zizifo eziphazamisayo, iminqweno yemvubelo kunye neminye imiba yokutya yokugaya ingakwazi ukunikezwa kummkeli wefecal.
Ngaphambi komnikelo, umnikeli unokucelwa ukuba athathe urhulumente we-antibiotic ukulungiselela umnikelo.
> Imithombo:
> I-Fecal Microbiota Ukutshaliswa kwe-Clostridium engapheliyo. ULJ Brandt, u-SS Reddy. Umbhalo we-Clinical Gastroenterology.
> I-Clostridium ephindaphindiweyo i-Colitis: I-Case Series Ebandakanya iziguli ezingama-18 eziphathwa nge-Donor Stool ezilawulwe ngeTayogastric Tube. UJohannes, uGessert noBakker.