I-Colazal (i-Dosedium ye-Balsalazide) Imibuzo ebuzwa rhoqo

by Amber J. Tresca

I-Colazal ivunyelwe ukusetyenziswa kwi-Ulcerative Colitis

Yintoni iClazal?

I-Colazal (i-balsalazide disodium) isetyenziselwa ukunyanga i-colceric colitis. Kuvunyiwe ukusetyenziswa kwizigulane ngaphezu kweminyaka emi-5. I-Colazal iyilwaphulo echasayo ekhishwa emathunjini amakhulu , apho isichengisi sisebenza ngokusemgangathweni ukunciphisa ukutshaya okubangelwa yi-ulcerative colitis.

I-Colazal iphuma kwi-5-aminosalicyclic-acid (5-ASA), yinkalo yesilwanyana esasetyenziselwa ukunyanga i-ulcerative colitis iminyaka emininzi.

Kukho abanye abantu abachasene nale klasi yeziyobisi, ngoko xelela umboneleli wakho wonyango kwanoma yiyiphi na into ehambayo kwizilwanyana ezi-5 ze-ASA. I-Colazal isizukulwana esilandelayo sezilwanyana ze-5-ASA kwaye siklanyelwe ukukhutshwa ngqo kwi-colon, apho kufuneka iyenze umsebenzi wokunciphisa ukuvuvukala.

Uninzi lweziphumo ezisecaleni lubunobumba kwaye ziquka intloko kunye nesicefe. Iziphumo ezibi kakhulu zingabonakali, kodwa phakathi kwazo zibandakanya umchamo wegazi okanye isitofu kunye nesisu. Xa uthatha uClazal, qhagamshelana nodokotela wakho nayiphi na imibuzo malunga nemiphumo emibi okanye iimpawu ezintsha okanye ezingavamile.

I-Colazal ithathwa njani?

I-Colazal isithathwa ngokuqhelekileyo ngabantu abadala kwizidakamizwa ezintathu zee-capsules kathathu ngosuku okanye ngaphandle kokutya. Isilwayo savunywa ukuba abantwana abaneminyaka emi-5 ukuya kwe-17 emva kokufundiswa kwiqela elincinane labantwana; iisisombululo ezimbini ezifundwayo ziyi-capsule enye kathathu ngosuku kunye neepsulle ezintathu kathathu ngosuku. I-Colazal iboniswe ngokukhuselekileyo ukuba ithathe iiveki eziyi-8 (iintsana) okanye iiveki ezili-12 (abadala).

Ukuba ama-capsules akakwazi ukuginywa, anokuvulwa kunye nezinto ezifafazwe kwi-appleauce. I-appleauce kufuneka idliwe kwangoko. Ukuba iClazal ithathwa ngale ndlela, inokubangela ukuba ibala libe ngamazinyo okanye ngolwimi.

Kutheni iColazal ibhalwe?

I-Colazal inqunyelwe ukunyanga ukuvuvukala kwikoloni edibene ne-mildness to moderately severe ulcerative colitis.

Uninzi lwamachiza lukhutshwa kwikolon, apho lunokunciphisa ukuvuvukala.

Yintoni endiyenzayo xa ndilahleka iDose?

Ukuba ulahlekelwa umthamo, thatha ngokukhawuleza ukuba ukhumbule. Ukuba umthamo wakho olandelayo kufuneka uthathwe kungekudala, thabatha nje loo dosi. Musa ukuphindaphinda kabini okanye uthathe idosi enye ngexesha.

Ngubani Akufanele athathe Colazal?

I-Colazal ayilunyanzelwanga kubantu abane-allergies kwi-aspirin okanye kwimveliso efana ne-aspirin. I-Colazal ayizange ifundwe ukusetyenziswa kwabantwana abangaphantsi kweminyaka emi-5.

Tshela ugqirha wakho ukuba unayo na le miqathango ilandelayo:

Isifo sesibindi
Izifo zesifo
I-pyloric stenosis

Ziziphi iimpembelelo?

Ingxaki, kodwa engavumelekanga, imiphumo engaphantsi kweColazal ibandakanya umchamo wegazi, utywala, kunye nokuphuma kwegazi. Eyona mininzi, iziphumo eziqhelekileyo ziquka ukuncwina, uhudo, okanye intloko. Jonga iphepha leempembelelo zeColazal kwiphepha leempembelelo ezinobungozi.

Ngaba zikhona naziphi na iziphumo zoBucala?

I-Colazal ayiyazi ukuba ibangela nayiphi na imiphumo yecala yezesondo kumadoda okanye ngabafazi.

Ziziphi iiMilisi ezinokuthi zisebenzisane neClazal?

I-Colazal ayizange ifundwe ngokusebenzisana namanye amayeza. Kucingelwa ukuba i-antibiotics ingabangela ukuba uColazal asebenze ngaphantsi.

Ngaba kukho ukubandakanyeka kokutya?

Akukho ukusebenzisana kokutya kunye noClazal.

Ngaba u-Colazal ukhuselekile ngexesha lokukhulelwa?

I-FDA ifake iColazal njengesiqhelo seB. Impembelelo eyenziwa nguClazal kumntwana ongakazalwa akafundiwanga ngokubanzi. I-Colazal kufuneka isetyenziswe kuphela ngexesha lokukhulelwa xa kuyimfuneko. Yazisa ukuba ugqirha ukuba uyakhulelwa ngelixa uthabatha uClazal. Ayaziwa ukuba uClazal angadlulela ubisi lwebele kwaye athinte umntwana osana.

I-Colazal Ingakanani Ingathathwa Ngokukhuselekileyo?

Ukhuseleko kunye nokusebenza kweClazal emva kweveki ezili-12 kubantu abadala kunye neiveki ezi-8 kubantwana (ngaphantsi kweminyaka eyi-17) abaziwayo.

_Imithombo:

_{Salix Pharmaceuticals.} _{"Colazal - UC Treatment." Salix Pharmaceuticals, Inc. 2013. 15 Septemba 2013.}

_{US Food and Drug Administration.} _{"I- Dosedium ye-Balsalazide (ithengiswa njengeClazal). " Iziyobisi @ FDA 11 kuMatshi 2007. 15 Septemba 2013.}