I-syndrome eyaziwa ngokuba yi-leukoencephalopathy syndrome, okanye i-RPLS, iyimeko engabonakaliyo, enjenge-stroke ebangelwa ukuvuvukala kwengqondo. Ukuhlaziywa kwe-leukoencephalopathy emva kwexesha eliqhelekileyo kudibana neqhekeza legazi eliphezulu . Nangona kunjalo, i-syndrome ingakhula ngendlela engalindelekanga ngaphambi kokuba isombulule. Kwaye, kuba akuqinisekanga ukuba i-stroke okanye isiganeko esifana nesigxina siya kugqitywa, kubalulekile ukufumana unyango malunga neempawu ze-neurological.
Ukuba uye watshelwa ukuba wena okanye othandekayo uye waba ne-posterior leukoencephalopathy syndrome, mhlawumbi unemibuzo embalwa malunga nayo.
Enye yeempawu ze-RPLS kukuba ibuyiswa kwakhona, oko kuthetha ukuba le meko yesikhashana kwaye iimpawu zayo kunye neziphumo ze-MRI zixesha elide. Imimandla yengqondo echaphazelekayo yile syndrome ikhona emva kwengqondo. I-Leukoencephalopathy ichazwa njenge-clouding of consciousness, ukudideka, okanye isimo sengqondo esishintshile ngenxa yemeko echaphazela ummandla omkhulu wengqondo. Kwimeko ye-RPLS, ngumcimbi omhlophe wengqondo echaphazeleka kakhulu. Le meko yi-syndrome. I-syndrome yinkqantosi yeempawu zesifo esiqhelekileyo kunye naso nasiphi na isifo sidlulayo okanye 'sisenza.'
I-RPLS yi-syndrome apho isiqwenga soxinzelelo lwegazi siphakamisela ukukhukhumeza okubuyiselwayo kummandla omhlophe wengqondo, ngaloo ndlela ekhokelela kwisimo sengqondo esitshintshileyo esesigxina.
Ukungafani kweRPLS
Njengoko kuvela, iimpawu eziphawulwe kule meko azichazwanga ngokucacileyo njengoko isichaza sakhe sichaza, njengoko i-RPLS iboniswe ukuba ibangele iimpawu ezahlukahlukeneyo, zonke ezo zinomlinganiselo omkhulu wobunzima, kunye nobude. Ezi ziqhelekileyo kwezi zinto, njengoko kuchazwe ngophando olulunye, zibandakanya i-encephalopathy (i-92%) yokuthintela (87%), intloko (54%) kunye neengxaki ezibonakalayo (39%).
Kodwa akuzona zonke iimeko zeRPLS ezibuyiselwayo, ezantsi emva, okanye ezihlobene nokuvuvukala kwimiba emhlophe. Ngoko phantse nayiphina indawo yengqondo ingathinteka yi-RPLS, kwaye ezinye iimpawu zentlungu zingakho.
Ukuxilongwa
Ukuxilongwa kwe-RPLS kwenziwa ngokugqithisa ngokugqithisileyo kwezokwelapha okubandakanya imbali echanekileyo yeempawu ezibangelwa isigulane, ukuhlolwa kwempilo yengqondo, i-MRI yengqondo, kunye nobukho bexinzelelo lwegazi malunga nexesha lezehlakalo. Olunye uphando kuphando lubonisa ukuba abanye abantu bangabandezeleka kwiRPLS phambi koxinzelelo lwegazi oluqhelekileyo. Oku kwenzeka kwiimeko ezibizwa ngokuba yi-eclampsia, edla ngokuqhelekileyo inxulumene nokukhulelwa kwangaphantsi okanye abasebenzi kunye nokunikezelwa. I-encephalopathy kunye neukoencephalopathy nazo zingenzeka kubantu abasebenzisa imithi ethile.
Ngokuqhelekileyo, i-MRI yengqondo yezigulane ezine-RPLS ibonisa ukubonakala kokuvuvukala kwimiba emhlophe yendawo engaphantsi kwengqondo kwimiba ekhohlo kunye nekhohlo. Nangona kunjalo, kwezinye iimeko, i-RPLS inokubandakanya iindawo eziphambi kwengqondo okanye ezinye iindawo zengqondo, kwaye inokubandakanya umbandela. Ukongezelela, amaninzi amaninzi e-RPLS ashiywe abasindileyo kunye nomonakalo wengqondo esisigxina, nangona kwiimeko ezininzi izigqibo zokuvuvukala kwenzeka.
Ukuphuculwa kungaqinisekiswa ngokugqithisileyo kweMRI yengqondo.
Unyango
Unyango lwe-RPLS lujolise ekulawuleni ngokuthe ngqo uxinzelelo lwegazi kunye namanqanaba omzimba emzimbeni. Ukongezelela, ukuthintela nokunyanga ukuxhatshazwa kuyimfuneko ebalulekileyo yokulawulwa kolu meko. Ukujonga ngokukhawuleza iimpawu ezifana neentloko ziyinxalenye ebalulekileyo yokumisela utshintsho oluphuthumayo kwimeko.
Prognosis
Ngokuqhelekileyo, iimpawu zisombulula kwiintsuku ezimbalwa ukuya kwiiveki emva kokuqala kwe-RPLS. Nangona kunjalo, njengazo zonke iziqulatho zokubetha okanye ukukhwabanisa kweminye, kunokubakho iimpawu eziseleyo ezivela kumonakalo wengqondo.
Ulungiswe nguHeidi Moawad MD
Imithombo:
> Vivien H. Lee, MD; Eelco FM Wijdicks, MD; Edward M. Manno, MD; UAlejandro A. Rabinstein, MD; Uvavanyo lwezonyango lwe-Leukoencephalopathy Syndrome; Arch Neurol. 2008; 65 (2): 205-210.
> JP Mohr, uDennis W. Choi, uJames C. Grotta, uBryce Weir, uPhillip A. Wolf Stroke: I-Pathophysiology, i-Diagnosis, kunye noLawulo uChurchill Livingstone; Inkqubo yesine ( > 2004).