Ukuxhalaba kwamazinyo? Iiseli zesitembu zingaphendula zibe yimpendulo.
Kwabaninzi, isifo sezinyo singabangela ukwesaba kwabo kunzulu kunye nobumnyama. Ukunyaniseka kwabaninzi kukuba ugqirha wamazinyo angakuthumela ngeengcamango zengqondo, ukuze ungapheli ukuzama ukuphepha ukuqeshwa kwakho ngokupheleleyo.
Iingxaki zamazinyo akho ziba zibi ngakumbi xa zishiywa zingalindelekanga. Yingakho inani elikhulu labantu abanokukhathazeka kwamazinyo liphela ngokushiya ingxaki ingacatshulwa kuze kube yuleli.
Kwiimeko ezinjalo, ekugqibeleni unokuhlangabezana nesidingo sokutshintsha izinyo ezilahlekileyo.
Izifo eziqhelekileyo ezifana nokubola kwezinyo kunye nesifo segum kunokukhokelela ekulahlekeni kwezinyo. Ngokwesiko, izazinyo zamathambo ziye zasebenzisa amabhuloho wamazinyo kunye namazinyo omzimba ukuze athathe amazinyo afanelekileyo. Ukufakelwa kwamazinyo kwakungomnye wezinto eziphambili kwiikholeji ze-20 zenkulungwane kwiinkonzo zamazinyo. Ukutshintshwa kwamazinyo kunye nesithuba seminyaka yobudala kubonakala ngathi sifinyelele kwizinga elincinci letheknoloji.
Kodwa ukuqhubela phambili kwangoku kwi-stem yocwaningo lweeselula kuye kwabonisa ikusasa apho ukufakelwa kwamazinyo kungaba yikhompyutha yobudala.
Ngaba iiStem zeeNtshukumo zeNtsholongwane zendalo?
Unokuthi ukuba ngumntu kusenza senze ingqungquthela malunga namaninzi amazinyo esiwafumanayo ebomini bethu. Ngaphezulu kwexesha lakho lobomi, unamaqoqo amabini kuphela. Amazinyo anqabileyo okanye amazinyane aphelelwa lixesha xa uneminyaka eyi-12 okanye 13 ubudala. Oko kuthetha ukuba amazinyo akho omdala kufuneka akugcine ubomi bakho bonke.
Ezinye iindidi, okwangoku, zinamazinyo angenamkhawulo ngexesha lokuphila.
Ushaka uyingqungquthela ngokungafaniyo kule nto ingakwazi ukufaka amazinyo kwiiveki ezimbalwa nje. Umlomo womlomo wehaki mhlawumbi ushiya ukunyanzela into enye eyoyikisayo kunokuba ugqirha wamazinyo. Kodwa udoki bubungqina bokuba amandla okudala ukukhula kwamazinyo amatsha ukuze abe ngumdala.
Iingcali zenzululwazi ziye zathatha kwaye zijonge ngendlela eya kusetyenziswa iiselingi ukukhula kwamazinyo amatsha kumntu omdala.
Ubume bunokuba neenzuzo ezibalulekileyo ngaphezu kokufakelwa kwamazinyo. Izimpembelelo zamazinyo, ngenxa yeendleko kunye neyinkimbinkimbi, ayilona inkqubo ejwayelekile yamazinyo. Inqubo ebandakanya iiseli ezinokuthi ikwazi ukubonelela indawo efumanekayo kwaye ifikeleleke.
Izimpembelelo zamazinyo, umzekelo, azikwazi ukufakwa kubantu abaneemeko ezithile. Ukongezelela, abaninzi abantu bayesaba inkqubo yokufakelwa kwamazinyo . Kudinga ukuhlinzwa okwenziwa ngomlomo, okuye kwaqhubekela phambili ngokukhawuleza, kodwa nangona ukunyuka kweteknoloji, ukufakelwa kwamazinyo akungenazo iingozi. Ezinye zezinto ezingenakwenzekayo zibandakanya oku kulandelayo:
- Ukuphilisa ixesha
- Ixesha elide
- Iziganeko ezinzima zokungaphumeleli
- Ukungabi nophando lwexesha elide malunga nokuvelisa ixesha elide
Ngoko, ngeengqungqembe engqondweni, ngaba iiseli zegesi eziza kutshintsha amazinyo?
Ziziphi iiNtsholongwane zentambo?
Umzimba uqulethe iintlobo ezahlukeneyo zeeseli. Ukususela ekuzalweni, njengengqayi encinane, awuxhotywanga kuzo zonke iintlobo ezahlukeneyo zeeseli ezifunekayo emzimbeni. Iiseli zesitembu zikunceda ukuba udale zonke izitho ezahlukeneyo kunye neenkqubo ezenza wena . Ziyilungu elingenakuxhatshazwa elikwazi ukutshintsha kuwo onke iseli emzimbeni wakho.
Amaseli esitembu angatholakala kwiintlobo ezininzi zomzimba kwaye ancedise ukudala nokuzalisa umzimba wakho.
Ngokuqhelekileyo bangcwatyelwa ingqumbo, kunzima ukufumana indawo. Zivame ukuba zincinci kwaye zifihliwe phakathi kweeseli ezibonakalayo.
Iingcali zenzululwazi ziye zafumanisa ukuba amazinyo aphethe inkunkuma yamaseli e-stem, atholakala kumazinyane ezinsana kunye namazinyo amakhulu. Ezi iiseli zikwazi ukuziphindaphinda.
Amaseli ezinamazinyo angamazinyo angaba nezicelo kwiindawo ezininzi zesayensi yezokwelapha ngenxa yokuhambelana nomzimba womzimba. Enye ingxaki ngokufaka ii-cell stem ngumzimba onokuwagxotha ngokuphendula komzimba. Kodwa ngaphandle kokuba nemisebenzi enye kwezinye iinkqubo zonyango, isicelo esicacileyo ngokwenene sithatha indawo yezinyo.
Uphononongo luqala ukubonisa iindlela ezibonakalayo ekufakweni kwezinyo kunye neeseli zamazinyo ezinamazinyo.
Iingcali zenzululwazi ziyakwazi ukukhulisa amazinyo kwiimpawu zezilwanyana
Kuye kwaba nenqubekela phambili ephawulekayo ekusebenziseni iiseli ezibafileyo kwizifundo zezilwanyana. Amazinyo aphumelele ngempumelelo kwiKing College yaseLondon. Iqela labo lophando lidibanisa izicubu zomntu kunye nama-stem cells avela kwimizinyo enamazinyo ayenzayo. Iiseli ngokwabo zifuna ukunikezelwa kwegazi kwiimpawu ezijikelezayo ukuze zenze izinyo eziphilayo.
Olunye uphando lunamazinyo ngempumelelo lufakwe kwiilwanyana. Kwisiko se-Whys iHarvard, iqela lophando lifumene impumelelo kwizinyathelo zokukhula ezinamaqanda. Basebenzisa ubuchule ngokusebenzisa i-laser-power laser ukuze kusebenze amaseli angama-stem ukuze abuyele kwakhona isakhiwo sezinyo.
Ngaphandle kweYunivesithi yase-Columbia, uphando olulodwa luye lwayithatha kwisinyathelo esilandelayo. Apha, abaphandi bakwazi ukukhokela iiseli ezinamaqabunga ukudala i-scaffold yesithathu. Iziphumo zibonise ukuba iinoti elipheleleyo le-anatomically liyakhula malunga neveki ezili-9.
Umbuzo omkhulu kunye nazo zonke ezi zifundo kukuvelisa iziphumo kubantu. Ngokuqinisekileyo, ukwenza ii-rentistry kwiirath kwakungekho ngaphandle kwemingeni. Ngoxa i-dentin yayincinci ngokufana nento ekhula ngokwemvelo, ayifani ngokufanayo nabantu.
Umntwana (iStem Cell) Amanyathelo
Imingeni emikhulu ejongene nama-stem cell cells azalisekisa iziphumo zonyango ezithembekileyo zabantu. Esikhundleni sokutshintsha amazinyo onke, amangqamuzana angamazinyo anokunceda ukuphulukisa amazinyo njengesinyathelo sesikhashana kwisitulo samazinyo.
Ngokomzekelo, amazinyo ayaziwa ukuba afumane iiseli ezingaphilisa i-dentin. Kukho na amanyathelo aphakathi kwamaseli okugaya aphilise amazinyo. Ukubola kwezinyo, iiseli ezinamahloni ziyakwazi ukuphilisa isigxina phambi kokuba inyo ifuna unyango lwe-canal . Amaseli esitembu angakwazi ukulungisa umpopu wamazinyo kwaye aqondise umzimba wokuzivikela ukukhupha ibhaktheriya ebangela ukubola.
ILizwi
Enye into eqinisekileyo kukuba sonke sinamaseli esitshixo kumazinyo ethu. Esikhundleni sokuphosa nje inyolo ebhodini emva komxube, siyakwazi ukukhipha iiseli kwikamva xa zingasetyenziselwa ukuzalisa izinyo.
Xa abantu abaninzi behamba beza kugcina iiseli zabo, kungase kube ngumgangatho wokugcina iiseli ezinamazinyo ezigcinwe kumazinyo ethu. Okwangoku, amazinyo omntwana kunye namazinyo obulumko abaviwa abagqwesileyo kakhulu, kwaye ngoku kudla ngokuba ngaba silahlekelwa kakhulu. Amazinyo anempilo aqulethe la maseli amnandi kwaye angenza imimangaliso kwisihlalo sezinyo esikhathini esizayo.
> Imithombo:
> Arany PR, Cho A, Hunt TD, et al. I-Photoactivation ye-Endogenous Latent Transforming Factor Factor-β1 iLawula i-Dental Stem Cell Differentiation yoKuvuselela, iSayensi yeeNguqulelo zeSayensi, ngoMeyi 28, 2014:
Vol. 6, Issue 238, iphe. 238ra69.
> I-Bansal R, Jain A, Uhlolo-nkqubo lwangoku kwiinkonzo zeseli zamazinyo ezinamazinyo okuvuselela i-dentistry, J Nat Sci Biol Med. 2015 uJan-Jun; 6 (1): 29-34.
> Mao J, Ukuveliswa kwezakhiwo zinozinyo kwiirath, Columbia Technology Ventures