Umbuzo oqhelekileyo obuzwe ngabantu abanembali ye-penicillin yokungabikho komzimba kukuba ngaba bathatha i-cephalosporin. Oku kungenxa yokuba i-penicillins kunye ne- cephalosporins ziyi-antibiotikthi eziyilwe ngokufanayo.
Ngaphambi kokuba uphendule lo mbuzo, kubalulekile ukuba uqale ugqibe ukuba ngaba umntu okanye u-penicillin-into engafanelekanga engafanelekanga inokuchaphazela ukunakekelwa kwakho.
I-Penicillin: I-Beta-Lactam Antibiotic
I-Penicillin mhlawumbi ilungu eliyaziwa kakhulu liqela le- antibiotics ebizwa nge-beta-lactam. Zonke i-anti-antibiotics ze-beta-lactam ziqulethe isakhiwo esithile (esibizwa nge-ring beta-lactam) ngaphakathi kwe-molecular makeup.
Ngaphandle kwe-penicillin, ezinye i-beta-lactam ziquka:
- Iipenicillin ezifumaneka njenge-amoxicillin
- I-Cephalosporins njengoKeflex (cephalexin)
- I-Carbapenems njenge-Primaxin (imipenem)
I-Penicillin I-allergies: I-IgE-mediated Response
Isisombululo esifanelekileyo sokusasazeka kwipenicillin ngu-IgE-mediated (Type 1) impendulo ye-hypersensitivity response. Oku kuthetha ukuba xa uboniswe kwi-penicillin, isistim somzimba somntu (ukuba i-allergenic) siza kuhlakulela amaninzi omzimba we-IgE. Ezi zikhuhlane zihamba kwaye zibophelela kwiiseli ezithile ngaphakathi komzimba womntu, zibangela ukuba zikhulule iikhemikhali. Ezi ziikhemikhali yintoni ebangela ukuba iimpawu zendlela yokuphendula.
Iimpawu kunye neempawu ze-penicillin zithintela kwixesha elide ukuya kwiyure okanye ezimbini zokuthatha iziyobisi kwaye zibandakanya enye okanye ngaphezulu kwezi zinto zilandelayo:
- I-Skin Itching kunye / okanye imihlathi
- Ukubetha okanye ukubetha komlomo okanye ulwimi
- I-Angioedema (ukuvuvukala komlomo, amehlo, umlomo, okanye ulwimi)
- Ukuphefumula nokuphefumula
- Unzima ukugwinya
- Uxinzelelo lwegazi oluphantsi
- Lightheadedness
- Ukukhawuleza kwenhliziyo
Kutheni kuQinisekisa i-Penicillin True allergies Kubalulekile
Ngokutsho kwamaZiko okuLawulwa kweNtsholongwane kunye nokuKhusela , malunga nama-10 ekhulwini kubo bonke abantu baseMerika baxela ukungabikho komzimba kwi-antiictic anti-penicillin, kodwa ngaphantsi kweepesenti enye ngokwenene (esekelwe ukuvavanywa kwesikhumba).
Mhlawumbi, babetyala ngokugqithiseleyo njengepenicillin echanekileyo kwitshati yabo okanye i-allergies ixazululwe ngexesha-malunga ne-80 ekhulwini labantu abane-penicillin yokungabikho komzimba baphulukana ne-hypersensitivity emva kweminyaka eyi-10 (esichaza ukuba ayifumanekanga).
Ekubeni abantu abaninzi bacinga ukuba bayagula i-penicillin, akubalulekanga ukuba wena kunye nodokotela wakho ukucoca le nto ingalunganga. Oku kubangelwa ukuba i-anti-antibiotics ebanzi idlalwa njengenye indlela ye-penicillin.
Iziza-antibiotics ezibanzi ziyakwandisa umngcipheko wokushatyiswa kwe- antibiotic esikhathini esizayo kwaye zihlala zibiza kakhulu. Kwakhona, enye i-antibiotics egqityiweyo ngugqirha wakho ayiyi kuba yona nto iyona nto ifanelekileyo isifo sakho.
Ukuqinisekisa i-Penicillin Allergy: Ukuhlolwa kweSigqeba Ngaba yiGold Standard
Ukuze unqume ukuba ngaba unayo i-penicillin yokungasebenzi, ugqirha wakho uya kuthatha i-drug drug allergies yomlando kwaye isekelwe kuloo ngcaciso ukuba i- penicillin yokuvavanywa kwesikhumba (efuna ukudluliselwa kwesikhumba ) iyadingeka.
Ngokomzekelo, mhlawumbi uvelise isicupunu okanye isifo sovulo xa ugcina uthatha i-penicillin. Oku akusiyo into eyenzekayo, kodwa kunokuba isiphumo salo siphumelele.
Okanye mhlawumbi awuzange uthathe i-penicillin kodwa unelungu lentsapho elinesifo se-penicillin.
Oku, kwakhona, akuyiyo into engafanelekanga kuyo. Kule meko, ugqirha wakho uya kuqhubeka kwaye uphathe unyango lwakho nge penicillin okanye i-cephalosporin (ukuba iyasebenza).
Kwiphepha le-flip, ukuba awuqinisekanga malunga nokuphendula kwakho kwangaphambili kwi-penicillin, okanye ukuba ugqirha akahlali engaqinisekanga ukuba umphendulululo wawunokugula okanye awukho, uvavanyo olufunekayo ngummeli wezilwanyana kufuneka lwenziwe.
Ukukhuselwa kokuthatha i-Cephalosporin nge-penicillin yokungasebenzi
Masithi ubona umlwelisi, kwaye ukuvavanywa kwesikhumba sakho kukuhle kwipenicillin. Kule meko, kufuneka uphephe zonke i-penicillin.
Nangona kunjalo, usenokukwazi ukuthabatha i-cephalosporin ngaphantsi kwesikhokelo esiphezulu sakho soogqirha.
Oku kungenxa yokuba ipesenti kuphela yabantu (malunga neepesenti ezingama-3) kunye ne-penicillin yokungabikho komzimba kuzakuphendula kwi-cephalosporin-nangona kunjalo, impendulo ingabangela.
Uhlobo lwe-cephalosporin othabathayo luya kuqwalaselwa. Kungenxa yokuba nangona uphando lubonisa umngcipheko omncinci wokusabela kwi-cephalosporin kubantu abaneepenicillin yokungabikho komzimba, kukho enye i-cephalosporins yesizukulwana esisodwa ngaphandle kohlobo lwe-cephalexin (Keflex) kunye ne-cefazolin (i-Ancef) kubangele amazinga aphakamileyo okwenyukayo kubantu i-penicillin yokungabikho komzimba kunabantu abangenayo i-penicillin.
Kwi-flip ecaleni, i-cephalosporins yesibini kunye nesithathu, njenge-cefuroxime (Ceftin), cefprozil (Cefzil), cefdinir (i-Omnicef), ne-cefpodoxime (i-Vantin), ayibonakali ukuba ibangele ukuphazamiseka komntu kubantu abane-penicillin .
ILizwi
Umgca wenkalo kukuba ngelixa abaninzi abantu abanomlando we-penicillin ukungakwazi ukunyamezela ukunyamezela i-cephalosporins, oogqirha abaninzi basebenzisa ukuqaphela xa bechaza omnye, njengoko impendulo inokuthi ibe nzima.
Ukongezelela, kubalulekile ukuqonda ukuba kukho izinto ezininzi ezibandakanyekayo kwisigqibo sokumisela i-cephalosporin, njengoluhlobo lwesifo esilufuna ukuphathwa kunye nokufaneleka / ukutholakala kwee-antiicticin / non-cephalosporin antibiotics ezingasetyenziswa.
> Imithombo:
> Blumenthal KG, i-Shenoy ES, i-Hurwitz S, i-Varughese CA, i-Hooper DC, i-Banerji A. Imiphumo yesistim sokungenwa kwemfuyo kunye ne-antibiotics echaza umkhombandlela kwi-antibiotics yabanikezeli bezonyango abanokugula. J Allergy Clin Immunol Pract . 2014 Jul-Aug; 2 (4): 407-13.
> Blumenthal KG, Solensky R, Ukuhlolwa kweengxaki zezilwanyana ze-penicillin zokupheliswa komzimba: Izicwangciso zokuhlola i-Skin-based based diagnostic kunye ne-reactivity nezinye i-beta-lactam antibiotics.
> D ePestel DD et al. Ukusetyenziswa kweCephalosporin kwonyango lwezigulane ezine-penicillin. UJ Am Pharm Assoc (2003). 2008 Julayi-Aug; 48 (4): 530-40.