Ubume bendalo, i-Genetic, kunye ne-Allergic Factors
I-eosinophilic esophagitis, okanye i-EoE, yayisetyenziselwa ukuthathwa njengengxaki engaqhelekanga. Nangona kunjalo, ngeendlela zokuvavanya ngcono kunye nokuqonda okungcono umbahluko phakathi kweGERD kunye ne-EOE , ngoku sele ithathwa ingxaki eqhelekileyo yabantwana kunye nabantu abadala abaneengxaki zokugwinya. Akucaci ukuba ukusabalalisa kwe-EoE kwanda okanye sesanda kuqonda ngakumbi i-eosinophilic esophagitis.
I-eosinophilic esophagitis ifunyaniswa ngokufumana i-biopsy ye-esophagus nokubona ii-eosinophil phantsi kwe-microscope yamandla ephambili. I-Eosinophil iyingqambela zegazi ezimhlophe (inxalenye yesistim e-immune system) esinokudityaniswa nokuvuvukala kunye nokuhambelana nokunyamezela. Ukuqonda i-EoE kwakusisiseko sokuqala, njengoko kwakunxulumene nolunye uhlobo lwesifo se-reflux kwaye lugcinwe kuphela ngeproton-pump inhibitors (uhlobo lonyango lwesifo se reflux), njenge-Prilosec.
UkuPhepha kunye neziMpawu
Kukho uphando oluqhubekayo lokunceda ukuqonda ngokubaluleka kokubili ukusabalalisa kunye nemingcipheko enxulumene ne-eosinophilic esophagitis. Amadoda abonakala ukuba angama-3 amathuba ngaphezu kwamabhinqa ukuba abe ne-EoE kwaye afunyanwe kubantwana, abantu abadala kunye nabantu abadala. Izikhalazo eziqhelekileyo abantu abanalo xa befuna unyango lwezokwelapha zi:
- Unzima ukugwinya (dysphagia)
- Ukuguquka
- Ukunyanzelisa
Ngaba I-Acidx Yenza I-Reflux Yenza I-Eosinophilic Esophagitis?
Iingcamango zangaphambili malunga ne-caosation ye-eosinophilic esophagitis zazibandakanya umonakalo we-esophagus obangelwa yi- GERD okanye i- acid reflux ukusuka kwisisu ukuya kwi-esophagus.
I-asidi iya kubonakalisa umgca wesigxina kwaye ivumele i-eosinophil ukuba ihlasele. Kwakungekho phakathi kwe-1990s xa le ndlela iqala ukukhutshwa. I-GERD ayisakholelwa ukuba yimbangela ye-EoE.
Izinto zobungozi bendalo
Imiba yendalo iyabonwa njengeyona nto inokwenzeka ekufumaneni i-eosinophilic esophagitis.
Ingqiqo yale nto ifana neemeko zemingcipheko engqongileyo ehambisana ne-asthma kunye neengxaki zesikhumba ezivuthayo. Kucingelwa ukuba ukungabikho okwaneleyo kwiibhaktheriya kunye nezinye izilwanyana ezincinci ebomini kungabangela imbangela ye-EoE. Iimeko ezinokunciphisa iintsana kwixabiso elifanelekileyo leebhaktheriya ziquka:
- Icandelo leSesareya ngokuhanjiswa kwezesondo
- Ukuzalwa kwangaphambili
- Imfuneko yokuqala yamachiza okubulala iintsholongwane
- I-formula-fed-fed vs isondlo
- Ukuhlala kwindawo ephantsi yoluntu
Ngexesha lekhosi ukukhulelwa, umntwana wakho unesisu esisinyulu (inkolelo eqhelekileyo, kodwa ingxabano encinane ngaphezu kwalokhu) okanye ukugqithisa kakhulu kwiibhaktheriya. Ngexesha lokunikezelwa kwesisu, umntwana wakho uya kubonakala kwiibhaktheriya eziza kusebenza njengeqalo lokuqala ekuphuhlisweni kwebhaktheriya ezifanelekileyo zamathumbu. Oku kutyhila akukwenzeki ngexesha leqhekeza. Kubalulekile ukuba uqaphele ukuba kukho izizathu ezininzi ezifanelekileyo zokuba necandelo lesigxina kunye neendlela ezifanelekileyo zokuhambisa kufuneka zixoxwe kunye nomgqirha wakho.
Izinto zobungozi be-Genetic
Uphando lwe-Genetic ngumhlaba oqhubekayo wokufunda. Ngokumalunga ne-eosinophilic esophagitis, kukho izinto ezininzi zokuqwalasela ngokuphathelele kwimfuza. Kukho izifundo ezibonisa ingozi eyanciphayo yokuba ne-EoE ukuba umntakwabo okanye umzali unesi sifo.
Phantse ii-2 kwiintsapho ezingama-100 zazinomngcipheko wentsapho, nangona kubonakala ukuba izinto ezinobume bemeko zinokubambisana. Oku kuthetha ukuba usengozini yentsapho inokuba yintoni ehambelana nemimandla engqongileyo echazwe ngasentla.
Nangona kunjalo, uphando oluye lwafumanisa izifo zentsholongwane ezithintela iimpendulo zomzimba wakho zomzimba ezingasenza ukuba ufumane i-eosinophilic esophagitis:
- Ukuphazamiseka kwimbane yokugcoba
- Ukuqhaqha kwamanzi
- Ukugqabhuka okungapheliyo
Ukungaphazamiseki kwindawo yokugcina isisindo kuvumela ukunyuswa kwe-eosinophil kwi-esophagus xa iboniswe kwizilwanyana. Ukuvuvukala okunxulumene ne-eosinophilic esophagitis kwakha iisetyhula ezinamathanga phakathi kwamasongo.
Kukho ukuhlala kubekho umbane okhuphayo ukusuka kwizicubu ngenxa yesibindi, esibizwa ngokuba yi-exudate. Ixesha elide, okanye elingapheliyo, ukuvuvuka ekugqibeleni kukukhokelela kwi-fibrosis, okanye ukunyuka okanye ukonakala okunciphisa isisu. I-Fibrosis yenye yezizathu zokubangela ukuba unokutya kubambelele kwisisu sakho ukuba unayo i-EoE.
Izinto zeengozi zeAllgen
Esinye seziganeko ezichongiweyo ezisemgangathweni ekuphuhliseni i-eosinophilic esophagitis yintlungu yokutya. Kwiimeko zokutya kokutya, i-ENT yakho inokukunceda ekulawulweni kokutya kweempawu zakho. Ukutya okuqhelekileyo okudibana ne-EoE kubandakanya:
- Iimveliso zederi
- Egg
- Soy
- Ngqolowa
Ukunyuka kokusingqongileyo kungadlala indima ekuphuhliseni i-EoE. Imiba engqongileyo yemingcipheko ibandakanya ukunyamezela:
- Izibungu zothuli
- Izilwanyana zezilwanyana
- Pollen
- Molds
Unokwazi ukuba iimpawu zakho ze-EOE ziba zibi nakwixesha le-pollen count. Uyakubona umgogodla ukuba uqhubeke nokuvavanya ukucacisa i-allergies engase ibe yingozi ngakumbi. Ukuba unempilo yeempawu ze-EoE ezibangelwa zizilwanyana zendalo, kubalulekile ukuzama ukususa lezi zifo ezivela ekhaya lakho .
Imithombo:
I-American Academy ye-Allergy Asthma & Immunology. (2015). I-Eosinophilic Esophagitis (EoE).
Furuta, GT, & Katzka, DA (2015). Eosinophilic Esophagitis. N Engl J Med. 373: 1640-1648. I-doi: 10.1056 / NEJMra1502863.
Kapel, RC, Miller, JK, Torres, C., Aksoy, S., Lash, R. & Katzka, DA (2008). I-eosinophilic esophagitis: isifo esixhaphakileyo e-United States esichaphazela onke amaqela eminyaka. Gastroenterology. 134 (5): 1316-21. i-doi: 10.1053 / j.gastro.2008.02.016.
Neu, J. & Rushing, J. (2011). I-Caesarean ngokumalunga ne-Vaginal Delivery: Iziphumo zexesha elide kunye ne-Hygiene Hypothesis. Iklinikhi yasePerinatol. 38 (2): 321-331. i-doi: 10.1016 / j.clp.2011.03.008.