Ukuthatha i-Elavil yokubuyisela ubuhlungu obungapheliyo

Amitriptyline

U-Elavil (amitryptyline) yonyango elinokusetyenziswa ezininzi. Sekude kusetyenziselwa unyango lwexinzelelo kodwa ngamanye amaxesha unikezwa njenge-adjuvant ("kunye") neyeza zentlungu kubantu abaneentlungu ezingapheliyo.

Yiyiphi i-amitryptylline eyiyo, yintoni ebonakalayo ngentlungu, yintoni imiphumo emibi, kwaye yiyiphi intsebenziswano yeziyobisi ezinokuthi zenzeke nale nkunkuma?

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Yintoni i-Amitriptyline?

U-Elavil (amitriptyline) yimithi echithwa ngumxhasi oye wachazwa ngaphandle-ilebula ukulawula intlungu engapheliyo. Ngenye yezilwanyana kwiqela leziyobisi ezibizwa ngokuba yi- tricyclic antidepressants .

I-Elavil isetyenziswa rhoqo kunye namanye amayeza. Amachiza asetyenziswe ngale ndlela abizwa njengamayeza enhlungu entle . Ayisoloko isetyenziswe njengonyango lokuqala, kodwa kunoko emva kokunyanga okunye okulondolozo lweentlungu, ezifana ne-Advil (ibuprofen) kunye ne-Tylenol (acetominphen) ayizange iphumelele ekunciphiseni intlungu.

U-Elavil akayiyo yonyango (i-opioid), kwaye akukho nto ingumngcipheko wokulutha umlutha ngeyeza.

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Luhlobo luni lwe-Back Pain Ngaba i-Amitriptyline iyayiphatha?

I-Elavil ibonakala iyona ndlela iphumelele kakhulu kwi- neuropathic uhlobo lwentlungu engapheliyo. Ukufumana izilonda zentlungu, ngokuqhelekileyo oku kuthetha ukuba intlungu yakho idlula phantsi ingalo okanye umlenze. Unokuba nobunzima bokubamba okanye isithintelo sepini kwisandla sakho okanye umlenze.

Nangona intlungu kaElavil yokunciphisa izixhobo ezizimeleyo yempembelelo yayo yokuxinzezela, isilwanyana sisebenza ngokunyusa inani leekhemikhali ezithile zeengqondo eziyimfuneko yokuzinza kwengqondo.

I-Amitriptyline isetyenziselwa ukunyanga i- fibromyalgia , yimeko ephawulwe yintlungu kunye neengongoma zethenda .

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Ngaba i-Amitriptyline iphumelele?

I-Amitriptyline yiyona nto ifunyenwe ngayo yonke i-tricyclic antidepressants. Sekusetyenziswa ukususela ngee-1960.

NgokukaDkt. Kathleen Fink, uMlawuli weeNkonzo zoPhando kwiSizwe soBuhlengahlengiso eWashington DC, eli liyeza lisebenziswa ngenxa yokuphuhliswa kwe-anti-depressant entsha ye-tricyclic.

UFink uthi oogqirha abanako ukukhululeka ukumisela i-amitriptyline ngenxa yengxaki engapheliyo yintlungu ngenxa yokuba iziphumo zempembelelo zingenza uzizwe uxhonywe kusasa. "Enyanisweni," utsho, "i-amitriptyline yinkonzo efanelekileyo kwaye engabizi ukulawula ubuhlungu obungapheliyo, ngokukodwa ukuba unenkinga yokulala."

Ucwaningo lwe-2014 olupapashwe kwi- Journal of Neurological Science ludanisa i-amitriptyline kunye neLyrica okanye i-pregabalin (esinye isilwanyana esinikwe intlungu yesifo senhliziyo) ukunciphisa intlungu, kunye nokukhubazeka ngokomzimba. Abaphandi bafumanisa ukuba nangona bobabini bebuhlungu obuphumelelayo, i-amitriptyline yanciphisa kakhulu ukukhubazeka, ngokunjalo.

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Amitriptyline Isisombululo

Xa u-Elavil isetyenziselwa ukulawula intlungu emva okanye entanyeni, umthamo uphantsi (malunga nesiqingatha, nangona oku kuya kuhluka) kunokuba kuthatyathwa ukudandatheka.

Ugqirha wakho uya kukuqalisa kwi dosi ephantsi kakhulu kwaye unyuke phezulu ukuya kwiveki nganye de kube yintlungu yakho kwaye / okanye iziphumo ezibi ziba nzima kuwe.

Imiphumo emihle isoloko ivela ngokukhawuleza xa le nkunkuma ithatyathwa ngenxa yokubuhlungu okungapheliyo xa kuthelekiswa xa isetyenziselwa ukulawula ukuxinezeleka.

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Amitriptyline Side Effects

Kubalulekile ukuba uqaphele imiphumo emibi ye-amitryptyline ngaphambi kokuba uqale le nkunkuma.

Ngenxa yokuba i-amitriptyline ivunyiwe yi-FDA ukuphatha uxinzelelo, inokuchaphazela isimo sengqondo, kubandakanywa ukwandisa umngcipheko wokuzibulala. Kodwa kwinqanaba lezinto, i-amitriptyline inomngcipheko wokuzibulala.

Ngokomzekelo, isifundo se-2015 sabantu abapapashwe kwiBritish Medical Journal sabona ukuba kubantu abanengxaki yokuzibulala, i-amitriptyline ngaphezu komnyaka omnye bekuyi-0.02 ekhulwini. Ngokuqinisekileyo abantu abahlala nexinzelelo banomngcipheko ophezulu wokuzibulala ngaphandle kwale nyanga. Ukuba nabani na ohlala kwintsapho yakho baneengxaki ze-bipolar okanye bazibulale, ugqirha wakho unokucebisa ukuba angasebenzisi le mayeza.

Ukuba ukhulelwe okanye uncelisayo, kukulungele ukuhlala kude ne-amitriptyline okanye i-Elavil, kuba isichengisiso sinokudluliselwa kumntwana wakho.

U-Elavil unokubangela iingxaki kubantu abane-arrhythmias (iziqhelo zentliziyo ezingavamile) kunye nezinye iintlobo zesifo senhliziyo, kwaye aphethwe ngabantu abangaphezu kwe-60 ubudala.

Iziphumo ezincinci ezingaphantsi kwe-Elavil ziquka umlomo owomileyo nokulala.

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I-Amitriptyline kunye ne-Drug Interactions

Kukho inani lamachiza asebenzisana ne-amitryptyline .

Ukusebenzisana phakathi kwe-Elavil kunye nezinye iziyobisi kunokunyusa inani le-amitriptyline egazini lakho. Ngaloo ndlela, oku kunganyusa imiphumo emibi yeyeza. Ukusebenzisana kunokwandisa inetyhefu (okanye ukunciphisa ukuphumelela) kweziyobisi ozithatha kunye no-Elavil.

Kubalulekile ukuxelela ugqirha wakho yonke into oyithathayo, ingaba unonwabo, ngaphezu kwe-counter okanye umiselweyo. Ngokomzekelo, ukulungiswa kwemfuyo yaseSt. John's Wort akufanele isetyenziswe nge-amitryptyline.

Ukubambisana okubalulekileyo kunokukwenzeka phakathi kwe-Elavil kunye nezinye izidumbu ze-muscle, i-anti-depressants, iziyobisi ezinengqondo ezingavamile, izigulane zengcinezelo yegazi ephezulu, imithi ye-thyroid, iipilisi zokulawula ukuzalwa, kunye nokunye. Ingqiqo enhle ukuthetha kunye nekhemistiki yakho kunye nokuba u-Elavil uyamisela.

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Xa Kufuneka Uphephe i-Amitriptyline: Iinkcazo

Kukho iimeko apho kukulungele ukuphepha ukuthatha i-amitriptyline ngokupheleleyo. Ezi zihlandlo zibizwa ngokuba "ukuchasene."

Ngokomzekelo, ukuba uthatha i-monoamine oxidase inhibitor (i-MAO yokudakumba okanye imithi ye-cisapride (engekho e-United States) akufanele uthathe i-amitryptyline.

Ekubeni u-Elavil unako ukwandisa okanye ukunciphisa umgangatho wezinye iziyobisi ozithathayo, soloko uthetha nodokotela wakho ngaphambi kokuyeka unyango lwakho.

Ngaphantsi kwindlela yokusetyenziswa kwe-Elavil ( Amitryptyline ) Kwi-Pain Backin

I-medication anti-depressant i-amitryptyline inokusebenza njengonyango oluxhamlayo lokuncedisa ukubuhlungu okungapheliyo. Kubonakala kusebenza ngokukhethekileyo intlungu ye-neuropathic, intlungu enokuthi igxilise umlenze wakho kwaye ibangele ubundlobongela, ukubetha, okanye ukuvuthwa kwe-pin-prick: ubuhlungu be-neuropathic buba yinto enzima kakhulu yeentlungu zokunyanga. Akuqinisekanga ukuba u-Elavil usebenza njani, kodwa umbane ubonakala uhlukile kunokuba usebenza njani ukudandatheka. I dose encinci isetyenziswa rhoqo.

Kukho imiphumo emibi neyingozi kunye ne-amitryptyline kwaye kubalulekile ukuthetha nodokotela wakho malunga nale. Ukongezelela, kukho izidakamizwa ezininzi ezinokusebenzisana ne-amitryptyline, kwaye ugqirha wakho kufuneka abe nolwahlu olubanzi lwemiqathango yakho yemithi, i-over-counter-counter, kunye nemithi yemithi ngaphambi kokumisela le nkunkuma.

> Imithombo:

> Fink, K., MD Incomo yoLwazi. Isibhedlele seSizwe sokuPhucula. Meyi 2011.

> Kasper, uDennis L .., u-Anthony S. Fauci, noStephen L .. Hauser. Iinqununu zeHarrison zeMithi yoPhakathi. ENew York: imfundo kaMc Graw Hill, 2015. Print.

> Urquhart, D., Wluka, A., Sim, M. et al. Ngaba i-Low-Dose i-Amitryptyline esebenzayo kwi-Management of Pain Down Back Pain? Iprotocol yoFundo yoLungiso oluLungisiweyo oluLungisiweyo. Zilingo . 2016. 17 (1): 514.

> van den Driest, J., Bierma-Zeinstra, S., Bindels, P., no D. Schiphof. Izibheno zeMisculoskeletal Izikhalazo: UkuHlola kwakhona. Uhlobo lweNtsapho . 2017. 34 (2): 138-146.