Uphando oluPhakamileyo luphakamisa isiqhagamshelo
Kwexesha elithile, iingcali ziye zatsholwa ukuba izifo ezithe zavela ebusaneni-njengobuncwane obunzima okanye ezibandayo-zingadlala indima ekuphuhliseni isifo se-celiac. Kodwa, uphando olutshanje olwenziwa eJamani lunokubonelela ngefowuni ekhonkrithi kule bango.
Isifo seCeliac sisifo somzimba sokuzivikela omzimba apho umntu akakwazi ukutya i-gluten kuba iya kutshisa kunye nokulimaza intombazana encinci.
Iimpawu ziqhelekileyo kubantwana kwaye zibandakanya ukubetha, isifo sohudo esingapheliyo, intlungu yesisu, nokuhlanza. Ukulandela ukutya okungahambisani ne-gluten, nangona kunjalo, ngokuqhelekileyo kuya kuthintela nayiphi na imiba enxulumene nemeko.
I-Early Infection-Celiac Disease Link
Abaphandi bahlalutya iirekhodi ezingama-295,420 iintsana ezelwe phakathi kuka-2005 no-2007 eBavaria, eJamani. Baqale bachonga inani lezonyango ezenzekayo kunyaka wokuqala wobomi ezazifuna unyango. Emva koko babala umngcipheko ochaphazelekayo wokufumanisa i-malaria celiac. Abantwana balandelwa phakathi kokuzalwa kunye neminyaka eyi-8.5 ubudala.
Kuphela, abantwana abangama-853 bahlakulele isifo se-celiac kwiminyaka emihlanu ubudala. Kula bantwana, i-820 yazo (amaphesenti angama-95,5) aphuhlise isifo se-celiac emva komnyaka wokuqala wokuphila. Abaphandi bafumanisa ukuba isisu-kunye nesifo esingaphantsi kwesifo sokuphefumula-sandise umngcipheko wesifo se-celiac.
Ukongezelela, izifo eziphindaphindiweyo zesisu zaphakamisa ingozi ngakumbi.
Kwisifundo esiphezulu esiphezulu sabantu, esapapashwe kwi -American Journal of Gastroenterology , abaphandi bavavanya abantwana abangama-72 921 baseNorway phakathi kokuzalwa kunye neminyaka eyi-8.5 ubudala. Abafana nabaphandi baseJamani, abaphandi baseNorway bafumanisa ukuba kukho intsebenziswano phakathi kwexesha elizayo lesifo se-celiac kunye nezifo ezithintekayo phakathi kokuzalwa kunye neenyanga ezili-18.
Izinto ezinokubangela iingxaki kunye nezinye izinto
Okwangoku, uphando olusisiseko lwabantu lubonise kuphela ukuba unxibelelwano phakathi kosulelo lwangethuba kunye nesifo se-celiac esilandelayo sikhona. Umbuzo omkhulu kukuba usulelo lwangaphambili lusenza njani isifo se-celiac. Kukho iindlela ezininzi ezinokuthi usulelo lube negalelo kwisifo se-celiac. Nazi ezi zimbini iingcamango:
- Iintsholongwane zinokubangela ukuveliswa kweeprotheni ezinokutsha (intreferononi) kwaye zikhokelela ekukhululweni kwe-transglutaminase, i-enzyme ebambe indima ebalulekileyo kwi-gluten yokukhupha impendulo yomzimba.
- Usulelo lunokunyusa ukutshabalalisa kwimbumba yegulane ngokuvumela ukuba i-gluten idlulele kwi-circulation-isinyathelo esibalulekileyo ekuphuhlisweni kwesifo se-celiac.
Kukho konke, izinto ezininzi-kungekhona nje ukusuleleka-nxaxheba zidlala indima ekuphuhliseni isifo se-celiac. Ngokomzekelo, kwelinye uphando olutshanje, olulandelayo abantwana abasuka e-United States naseYurophu, abaphandi bafumanisa ukuba izinto ezininzi zibandakanyeke ekuphuhlisweni kwesifo se-celiac emva kokusasazeka kokuqala kwesisu. Ezi ezinye iziganeko zendalo, i-rotavirus, i-rotavirus yokugonywa, ubuncinane bokusetyenziswa kwe-gluten yokuqala kunye nokuncelisa.
Ngokucacileyo, abaphandi bafumene ukuba umngcipheko wesifo se-celiac esandula sancipha xa abantwana abanikezelwa zizifo ezithintekayo kwisifo se-rolivirus bafumana i-rotavirus yokugonywa kwaye baziswa nge-gluten phambi kweenyanga ezintandathu.
(I-Rotavirus vaccine ikhusela i-rotavirus, imbangela enkulu yokurhuda kubantwana kunye nabantwana abancinci.)
ILizwi
Ukufumana uphando olutsha ngokubanzi luxhasa nje ukuba unxibelelwano phakathi kokusuleleka kwintsholongwane kunye nezifo ze-celiac zikhona-kungekhona ukuba le nxu lumano. Ngamanye amazwi, nangona usulelo lwangethuba kwaye emva koko izifo ze-celiac zibophelelwe, asiyazi ukuba ukusuleleka kosuleleko kubangela ukuba izifo eziphethwe yi-celiac.
Olunye uphando lubonakala lubonisa ukuba ukugonywa kwe-rotavirus kwangaphambili kunokubonelela ngezibonelelo ezikhuselekileyo malunga nesifo se-celiac. Ukongezelela, ukuqaliswa kwangaphambili kwesonka seengqolowa okanye ezinye iindawo ze gluten kunokunciphisa umngcipheko.
Kule ngongoma, asikwazi nje ngokwaneleyo ukwenza ukubikezela. Uphando olungakumbi lufanele lwenziwa.
Gcina ukhumbule ukuba i- CDC icebisa ukuba, ngeenyanga ezintandathu ubudala, zonke iintsana ziya kugonywa kwi-rotavirus. Emva koko, i-rotavirus inokuyingozi, oku kubangelwa ukuba izibhedlele ezingama-60,000 e-United States ngamnye ngonyaka. Okwangoku, kungenzeka ukuba i-rotavirus yokugonya ingadlala indima ebalulekileyo ekukhuseleni umntwana kwixesha elizayo leliacac ingabonwa njengebhonasi eyongeziweyo. Kodwa, ngaphambi kokuba uqalise i-gluten kwisondlo somntwana wakho, thetha nodokotela wakho-ingakumbi ukuba unokholo lwentsapho lokunyamezelana kwe-gluten.
> Imithombo:
> Beyerlein A, uDonnachie E, uZiegler AG. Izifo ekuqaleni koBomi nokuphuhliswa kwesifo se-celiac. Am J Epidemiol. 2017.
> I-MedlinePlus. Izifo zeCeliac.
> Kemppainen, KM, et al. Izinto ezinokwandisa ingozi yezifo ze-Celiac Ukuzimela ngokuzenzekelayo emva kokusweleka kwezilwanyana kwi-Early Life. I-Clinical Gastroenterology kunye neHepatology 2017; 15: 694-702.
> Mårild, K, et al. Izifo kunye neengozi zeSifo seCeliac ebuntwaneni: Isifundo soPhuhliso lwesizwe lonke. Am J Gastroenterol. 2015; 110: 1475-1484;